FA Synthesis

Question 1

palmitate synthesis pathwy

Answer 1

acetyl coa to malonyl coa through acetyl coa co2lase

malonyl coa stimulates fa synthase

Question 2

Carbons in Palmitate syn come form

Answer 2

acetyl coa

Question 3

acetyl coa’s in the palmitate syn

Answer 3

1st has a methyl end all others are converted to malonyl coa

Question 4

high chol/low fat causes

Answer 4

increased enzyme activity and need to make fat

Question 5

hi fat/ fasting

Answer 5

decreased enz activity and degrade fat need to degrade fat

Question 6

FA syn requires __ for eacj Carbon added

Answer 6

Requires 2 NADPHs for each two carbons added

Question 7

FA syn add 2 carbons at a time via

Answer 7

malonyl coa

Question 8

FA Synthase functions

Answer 8

ACP acyltransferase
ACP Manoyltransferase
beta ketoacyl ACP synthase
Beta ketoacyl ACP reductase
beta hydroxyacyl ACP Dehydratase
enoyl ACP Reductase
thioesterase

Question 9

describe citrate shuttle

Answer 9

in notes

Question 10

in FA synthesis from palmitate __ is a donor and __ is a receptor __?
product =

Answer 10

acetyl coa = donor
NADPH is a reductant
stearoyl coa

Question 11

hydroxylation uses __ F.A in mitochondria

Answer 11

short chain

Question 12

nerve tissue uses __ chain F.A

Answer 12

long

Question 13

POLY UNSATUTATED FATTY ACID FUNCTIONS

Answer 13

maintain proper mem fluidity

precursors to PGs TXBs and LKT

Question 14

3 proteins

Answer 14

desaturase, cytochrome b5,

NADPH-cytochrome b5 reductase

Question 15

what places a double bond on c9 and c10

Answer 15

stearoyl coa desaturase