F11 Flashcards

1
Q

Terminal cisternae

A

Portion of the SR nearest the T tubules

High density Ca++-ATpase

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2
Q

Titin

A

Cytoskeletal protein
Elastical
Extends from the Z line to the center of the sarcomere
Important for organization and alignment of the thick filaments in the sarcomer

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3
Q

Troponin complex

A

Troponin T: Tropomyosin
Troponin C: Ca2+
Troponin I: Inhibits binding of actin to myosin

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4
Q

Tropomodulin

A

Setting length of the thin filament

Located at the end of the thin filament

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5
Q

alpha-actinin

A

Anchor the thin filament to the Z line

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6
Q

Dystrophin

A

Localized on the intracellular surface of sarcelemma in association with several integral membran glycoproteins
Provides a structural link between the subsarcolemmal cytoskeleton of the muscle cell and the extracellular matrix

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7
Q

Beskriv vejen fra et synaptisk signal til kontraktion

A

1) Acetylkolin
2) Aktionspotentiale
3) Ca2+ frigives fra de terminale cisternae SR til myoplasma
4) Troponin-C
5) etc.

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8
Q

Twitch

A

The increase in Ca2+_intracellular

Lasts 20ms

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9
Q

Triad

A

T tubulus
+
Two opposing terminal cisternae

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10
Q

Feet(proteins)

A

Bridging proteins that close the 15nm gap between T-tubulus and terminal cristae

Ca2+-releasing channels: Ryanodine Receptor

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11
Q

DHP receptor

A

L-type voltage-gated Ca2+ channel
5 subunits
Interacts with RYR to release Ca2+

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12
Q

Calsequestrin

A

Low-affinity Ca2+-binding protein
Located in the lumen of terminal cisternae
Regulates Ca2+-level

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13
Q

Triadin and junctin

A

Bind both RYR and calseuestrin in terminal cisterna

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14
Q

HRC(histidine-rich calcium-binding protein)

A

Low-affinity Ca2+-binding protein in SR lumen

Binds triadin in a Ca2+-dependent manner

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15
Q

SERCA

A

Uptake of Ca2+ to SR

Opposite ffect of RYR

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16
Q

Sarcolumenin

A

Low-affinity Ca2+ binding protein
Present throughout the longitudinal tubules of the SR
Increases uptake by SERCA

17
Q

Nævn gliacellerne i CNS

A

Astrocytter
Oligodendrocytter
Microglia

18
Q

Nævn de afferente forbindelser til cortex cerebri

A
Thalamus
Mesencephalon
N. raphe og n. basilis
L. coeruleus
Ipsilaterale forbindelser
Kontralaterale forbindelser
19
Q

Nævn de efferente forbindelser til cortex cerebri

A

Lag II og III til ipsilaterale og contralaterale
Lag V til subkortikale områder
Lag VI til specifikke thalamiske kerner

20
Q

Angiv forbindelserne og funktioner i præfrontal cortex

A

Affernet information fra occipital-, parietal- og temporallappen

Vigtig for planlægning og igangsætning af målrettede adfærd

21
Q

Beskriv det hvide snit

A

Skrab af frontal cortex

22
Q

Beskriv parietallappens forbindelser og funktion

A

Afferent information fra sensoriske områder
Efferenter til motorisk og præmotorisk cortex til præfrontal cortex

Bevægelser

23
Q

Beskriv temporallappens forbindelser og funktion

A

Afferente fibre fra sensoriske systemer(auditive og visuelle)
Efferenter til peritale og frontale associationsområder

Behandling af auditiv information
Visuel behandling

24
Q

Beskriv hukommelsestyperne

A

Korttidshukommelse

Langtidshukommelse:

  • Explicit(Declarativ)
  • Implicit(Procedural)
25
Angiv områder involveret i deklarativ hukommelse
Hippocampus Amygdala Thalamus Frontral-, temporal- og parietallappen
26
Angiv områder involveret i procedural hukommelse
Præmotorisk cortex N. caudatus Putamen Cerebellum
27
Beskriv kravene til at udføre et godt EEG
Høj celletæthed Ensartet orientering Antal aktive synapser stort Aktiviteten er synkron
28
Angiv de forskellige hjernebølger
Beta: 14-30 Hz Alpha: 8-13.9 Hz Theta: 4-7.9 Hz Delta: 0.1-3.9 Hz
29
Beskriv petit mal og grand mal
Petit mal varer typisk under 15 sekunder Spike and wave Grand mal er mere ujævnt