F11

Question 1

Terminal cisternae

Answer 1

Portion of the SR nearest the T tubules

High density Ca++-ATpase

Question 2

Titin

Answer 2

Cytoskeletal protein
Elastical
Extends from the Z line to the center of the sarcomere
Important for organization and alignment of the thick filaments in the sarcomer

Question 3

Troponin complex

Answer 3

Troponin T: Tropomyosin
Troponin C: Ca2+
Troponin I: Inhibits binding of actin to myosin

Question 4

Tropomodulin

Answer 4

Setting length of the thin filament

Located at the end of the thin filament

Question 5

alpha-actinin

Answer 5

Anchor the thin filament to the Z line

Question 6

Dystrophin

Answer 6

Localized on the intracellular surface of sarcelemma in association with several integral membran glycoproteins
Provides a structural link between the subsarcolemmal cytoskeleton of the muscle cell and the extracellular matrix

Question 7

Beskriv vejen fra et synaptisk signal til kontraktion

Answer 7

1) Acetylkolin
2) Aktionspotentiale
3) Ca2+ frigives fra de terminale cisternae SR til myoplasma
4) Troponin-C
5) etc.

Question 8

Twitch

Answer 8

The increase in Ca2+_intracellular

Lasts 20ms

Question 9

Triad

Answer 9

T tubulus
+
Two opposing terminal cisternae

Question 10

Feet(proteins)

Answer 10

Bridging proteins that close the 15nm gap between T-tubulus and terminal cristae

Ca2+-releasing channels: Ryanodine Receptor

Question 11

DHP receptor

Answer 11

L-type voltage-gated Ca2+ channel
5 subunits
Interacts with RYR to release Ca2+

Question 12

Calsequestrin

Answer 12

Low-affinity Ca2+-binding protein
Located in the lumen of terminal cisternae
Regulates Ca2+-level

Question 13

Triadin and junctin

Answer 13

Bind both RYR and calseuestrin in terminal cisterna

Question 14

HRC(histidine-rich calcium-binding protein)

Answer 14

Low-affinity Ca2+-binding protein in SR lumen

Binds triadin in a Ca2+-dependent manner

Question 15

SERCA

Answer 15

Uptake of Ca2+ to SR

Opposite ffect of RYR

Question 16

Sarcolumenin

Answer 16

Low-affinity Ca2+ binding protein
Present throughout the longitudinal tubules of the SR
Increases uptake by SERCA

Question 17

Nævn gliacellerne i CNS

Answer 17

Astrocytter
Oligodendrocytter
Microglia

Question 18

Nævn de afferente forbindelser til cortex cerebri

Answer 18

Thalamus
Mesencephalon
N. raphe og n. basilis
L. coeruleus
Ipsilaterale forbindelser
Kontralaterale forbindelser

Question 19

Nævn de efferente forbindelser til cortex cerebri

Answer 19

Lag II og III til ipsilaterale og contralaterale
Lag V til subkortikale områder
Lag VI til specifikke thalamiske kerner

Question 20

Angiv forbindelserne og funktioner i præfrontal cortex

Answer 20

Affernet information fra occipital-, parietal- og temporallappen

Vigtig for planlægning og igangsætning af målrettede adfærd

Question 21

Beskriv det hvide snit

Answer 21

Skrab af frontal cortex

Question 22

Beskriv parietallappens forbindelser og funktion

Answer 22

Afferent information fra sensoriske områder
Efferenter til motorisk og præmotorisk cortex til præfrontal cortex

Bevægelser

Question 23

Beskriv temporallappens forbindelser og funktion

Answer 23

Afferente fibre fra sensoriske systemer(auditive og visuelle)
Efferenter til peritale og frontale associationsområder

Behandling af auditiv information
Visuel behandling

Question 24

Beskriv hukommelsestyperne

Answer 24

Korttidshukommelse

Langtidshukommelse:

• Explicit(Declarativ)
• Implicit(Procedural)

Question 25

Angiv områder involveret i deklarativ hukommelse

Answer 25

Hippocampus
Amygdala
Thalamus
Frontral-, temporal- og parietallappen

Question 26

Angiv områder involveret i procedural hukommelse

Answer 26

Præmotorisk cortex
N. caudatus
Putamen
Cerebellum

Question 27

Beskriv kravene til at udføre et godt EEG

Answer 27

Høj celletæthed
Ensartet orientering
Antal aktive synapser stort
Aktiviteten er synkron

Question 28

Angiv de forskellige hjernebølger

Answer 28

Beta: 14-30 Hz
Alpha: 8-13.9 Hz
Theta: 4-7.9 Hz
Delta: 0.1-3.9 Hz

Question 29

Beskriv petit mal og grand mal

Answer 29

Petit mal varer typisk under 15 sekunder
Spike and wave

Grand mal er mere ujævnt