Eye in systemic disease Flashcards

1
Q

What causes microaneurysm?

A

loss of pericytes

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2
Q

What are signs of non-proliferative retinopathy?

A
Microaneurysms
hard exudate
cotton wool patches
abnormalities of venous calibre
intra-retinal microvascular abnormalities
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3
Q

How do diabetics lose vision?

A

Retinal oedema affecting the fovea
vitreous haemorrhage
scarring/tractional retinal detachment

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4
Q

What are the classifications of retinopathy?

A
none
mild Np
moderate Np
severe Np
proliferative retinopathy
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5
Q

What are the classifications of maculopathy?

A

none
observable
referable
clinically significant

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6
Q

What surgery can help diabetic maculopathy?

A

Vitrectomy

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7
Q

What can alter the fundus?

A

hypertension

arteriosclerotic

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8
Q

What are features of hypertensive retinopathy?

A
Attenuated blood vessels - copper or silver wiring
cotton wool spots
hard exudates
retinal haemorrhage
optic disc oedema
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9
Q

Describe central retinal artery occlusion

A

sudden painless loss of vision
profound loss of vision
retinal nerve fibre layer becomes swollen except for at fovea (cherry red spot)
rarely recovers

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10
Q

Describe CRVO

A

Sudden painless loss of vision
Range of visual loss
need to determine degree of ischaemia

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11
Q

Describe Branch vein occlusion?

A

Painless disturbances in vision
may be assymptomatic
may be aware of loss of part of field

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12
Q

What are infective causes of uveitis?

A
TB
HZ
toxoplasmosis
candidiasis
syphilis 
lyme disease
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13
Q

What are non-infective causes of uveitis?

A
idiopathic syndromes
HLA-B27
Juvenile arthritis
Sarcoidosis
Behcet's disease
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14
Q

What is Giant Cell Arthritis?

A

Inflam of middle sized arteries

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15
Q

What is Giant cell arthritis assoc. with?

A

Polymyalgia rheaumatica

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16
Q

What are signs/symptoms of giant cell arthritis?

A
Headache
jaw claudication
malaise
raised PV
blinding condition
17
Q

What are features of extraocular thyroid eye disease?

A

Proptosis
lid signs - retraction, oedema, lag, pigmentation
restrictive myopathy

18
Q

What are features of ocular thyroid eye disease?

A
Anterior segment:
- chemosis
- injection
- exposire
- glaucoma
Posterior segment:
- choroidal folds
optic nerve swelling
19
Q

How do you manage thyroid eye disease?

A

Control of thyroid dysfunction
Lubricants
Surgical decompression

20
Q

What antibody is associated with SLE?

A

ani-DNA Ab

21
Q

What is dry eyes?

A

Keratoconjunctivitis Sicca

22
Q

What can rheumatoid arthritis cause?

A

Keratoconjunctivitis Sicca
Scleritis
Corneal melt

23
Q

What is Sjorgens syndrome associated with?

A

Keratoconjunctivitis Sicca
Xerostomia
RA
Inflammation of the lacrimal glands

24
Q

What are dermatology features of Marfans syndrome?

A

Steven’s-Johnson syndrome/erythema multiforme
maculopapular rash
Stomatitis
Conjunctivitis

25
Q

What happens with Stevens-Johnson syndrome?

A

Symblepharon
Occlusion of lacrimal glands
Corneal ulcers