extra Flashcards

1
Q

grey matter and white matter in brain composition

A

grey matter arranged in layers called laminae on the superficial surface of the brain

white matter bundles (the axon fibres) form tracts that connects to the grey matter

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2
Q

grey matter and white matter in spinal cord composition

A

grey matter arranged in columns within the spinal cord

white matter bundles (the axon fibres) form tracts that connects to the grey matter

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3
Q

anatomy of sympathetic system

A

origiinates in the thoracolumbar (thoracic and lumbar) sections of the spinal cord

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4
Q

anatomy of parasympathetic system

A

from the brainstem and the sacral sections of the spinal cord

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5
Q

corpus callsom

A

connects the right and left hemisphere

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6
Q

regulator of of cardiac, smooth and skeletal

A

troponin, calmodullin, troponin

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7
Q

relationship of of cardiac, smooth and skeletal

A

in unison, in unison, independent from other muscle fibres

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8
Q

linkage of of cardiac, smooth and skeletal

A

linked, linked, not linked

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9
Q

relationsh

A
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10
Q

Ca source of of cardiac, smooth and skeletal

A

intracellular, both intracellular and extracelluar, intracellular

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11
Q

origin of osteoblasts and osteoclasts

A

mesenchymal and haematopoeitic

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12
Q

they function through [phosphatase]
osteoblasts and osteoclasts

A

alkaline and acid

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13
Q

cortical bone and cancellous bone activity comparison

A

low and high

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14
Q

cortical bone and cancellous bone activity composition

A

80% and 20%

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15
Q

bone remodelling mechanism

A

microfracture forms during physcial stress
haemapoeitic stem cells –> pre osteoclasts –> osteoclasts

osteoclasts reabsorb the bone, leaving a reabsorption pit
mesenchymal stem cells –> pre osteoblasts arrive to the reabsorption pit
pre osteoblasts differentiate into osteoblasts to deposit collagen and mineralise it by depositing hydroxyapatite

osteoblasts mature into osteocytes which remain in the bone and maintain the bone integrity (can control the activity of osteoclasts and osteoblasts)

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16
Q

spleen role in immunity

A

filters antigens in the blood
contains lymphocytes and phagocytes to recognise, become activated and respond to foreign substanes in the blood

17
Q

lymph nodes role in immunity

A

filters antigens in the non-blood tisses
contains lymphocytes and phagocytes to recognise, become activated and respond to foreign substanes in the tissues

18
Q

mucousal associated lymhoid tissue (MALT) nodes role in immunity

A

filters antigens in the non-blood tisses
contains lymphocytes and phagocytes to recognise, become activated and respond to foreign substanes in the tissues

19
Q

blood vessel role in immunity

A

transports the immune cells throughout the body, to the sites of infection and inflammation

20
Q

how does macrophages and neutrophils act?

A

engulf pathogens, debris
release cytokines and chemicals and enzymes to break down pathogesn

21
Q

mast cels

A

release histamine and other chemicals in repsonse to pathogens and allergens

22
Q

eoisonphil

A

exocytes
releases chemicals and cytokines to attract phagoctyes to attack pathogens

23
Q

role of Histamine, antibodies, chemokines, and cytokines

A

histamine : increases blood vessel permeability to leak the plasma and components in the blood
antibodies : binds to specifc antigens to break them down
cytokines : signalling molecule / stimulate an immune response
chemokinds : atttracts immune cells to inflammation sites

24
Q

immunological tolerance

A

a process by which the immune system learns to recognise and tolerate self-antigens while still executing an effective immune response

25
Q

central tolerance

A

occurs in the thymus and bone marrow
during the development of T
cells and B cells, respectively.

during this process,any T or B cells that recognise self anitgens and responds is elimitated by a process called negative selection

the T cells and B cells that leave the thymys and blood marrow should all have the ability to distinguish between self and foreign atnigens

26
Q

peripheral tolerance

A

this occurs outside the blood marrow and thymus using a variety of mechanisms, e.g T-regulatory cells to prevent self reactive cells to hurt the body