export_exam 2 flashcards
Creatine Phosphate Energy Pathway
rapidly broken down to convert atp-adp, ONLY ENOUGH ENERGY FOR A FEW MUSCLE TWITCHES 8-10 seconds
Glycolytic Pathway
Rapid energy, anaerobic, INEFFICIENT only lasts 1-2 minutes
Oxidative Phosphorylation
very slow, efficient, 36mol ATP/Glucose molecule; Fatigue Resistant
Slow Oxidative Fibers
Type I- Low myosin ATPase activity, high oxidative capacity, i.e. Postural muscles
Fast Oxidative Fibers
Type IIa - High Myosin ATPase activity, high oxidative capacity, intermediate glycolytic capacity
Fast Glycolytic Fibers
Type IIb - high Myosin ATPase activity, high glycolytic capacity - fatigue relatively quickly; HAVE NO MYOGLOBIN (brings O2 to muscle)
Specific Force
force/cross-sectional area - Same for all types of fibers after “normalized” (divide by cross-sectional area)
Force of muscle
dependent on # of crossbridges. Additional: Sarcomeres in parallel increase force
Muscle Velocity/Speed
depends on rate of ATP hydrolysis/break off. Additional: Sarcomeres in series increase muscle speed/velocity
Fatigue Causes
- not enough time to clear Ca2+ with high frequency of AP firing
- Acumulation of K+ leading to inability to depolarize
Fatigue Definition + Effects
- failure of excitation-contraction coupling
- shuts down ability of DHP to interact with RYR