Exam III Flashcards
Sensory (afferent)
specialized to detect stimuli and transmit information about them
Interneurons (association)
lie entirely within the central nervous system
Motor (efferent)
sends signals predominantly to muscle gland cells
nerve
bundle of nerve fibers (axons) wrapped in connective tissue
Ganglion
knot-like swelling in a nerve where the cell bodies of neurons are concentrated
Central nervous system
consists of the brain and spinal cord, which are enclosed and protected by the cranium and vertebral column
Peripheral Nervous System
composed of nerves and ganglia (all of the nervous system except the brain and spinal cord)
Divisions of autonomic nervous system
sympathetic and parasympathetic
Multipolar neuron
one axon multiple dendrites
bi polar neuron
one axon, one dendrite
unipolar neuron
single process leading away from the soma
anaxonic
multiple dendrites; no axon
neuroglia
supportive cells
6 types of neuroglia
Oligodendrocytes (CNS), Ependymal (CNS), Microglia (CNS), Astocytes (CNS), Schwann (PNS), Satellite (PNS)
Why is myelin so important in the nervous system?
The myelin sheath is an insulating layer around a nerve fiber
How does an axon regenerate in the PNS?
The soma undergoes abnormalities, axon stump may sprout multiple growth processes while the distal end degenerates.
d. Muscle fibers deprived of nerve supply shrink, a process called denervation atrophy.
e. Near the injury, Schwann cells, the basal lamina, and the neurilemma form a regeneration tube.
The regeneration tube guides the growing sprout back to the original target cells, reestablishing synaptic contact.
g. When contact is established, the soma shrinks and returns to its original appearance, and the reinnervated muscle fibers regrow.
A change in potential may occur when
a neuron is stimulated
Local potentials
are graded (vary in magnitude depending on strength of stimulus), decremental, reversible if stimulation ceases, excitatory or inhibitory
action potentials
occur only when there is a high enough density of voltage-regulated gates; most of the soma cannot generate action potentials.
the refractory period
During an action potential and for a few milliseconds after, the neuron cannot be stimulated to fire again.
Where does a synapse occur?
at the end of an axon
Neurotransmitters fall into four major categories
Acetylcholine, Amino acid neurotransmitters, Monoamines, Neuropeptides
Neuromodulators
hormones, neuropeptides, and other messengers that modify synaptic transmission.
cholinergic synapse
- arrival of a nerve signal at the synaptic knob open voltage regulated calcium
- calcium triggers exoctytosis of synaptic vesicles releasing ACh
- empty vesicles drop back into the cytoplasm
- ACh diffuses across cleft to allow Na to enter and K to leave
- Na spreads out along the inside of the membrane producing postsynaptic potential
removal of neurotransmitter from the synaptic cleft is accomplished in three ways
diffusion, reuptake, degredation
excitatory postsynaptic potential (EPSP)
Any voltage change that raises the membrane potential closer to the threshold
inhibitory postsynaptic potential (IPSP)
Any voltage change that hyperpolarizes the membrane and makes it more negative than the RMP
Summation
the process of adding up EPSPs and IPSPs and responding to their net effect; it occurs in the trigger zone
Temporal summation
occurs when a single synapse generates EPSPs very quickly so that they have a cumulative effect.
Spatial summation
occurs when EPSPs from several different synapses add up to threshold at the axon hillock
labeled line code (qualitative information)
Each nerve fiber to the brain leads from a receptor that recognized a particular stimulus type, such as optic nerve fibers that carry signals only from light receptors in the eye
recruitment (quantitative)
additional neurons are brought into play as a stimulus becomes stronger, enabling the nervous system to judge stimulus strength by which and how many neurons are firing
4 types of neural circuits
diverging, converging, reverberating, parallel after discharge
engram
a pathway through the brain called a memory trace