Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BASIG q1 > exam 8b > Flashcards

exam 8b Flashcards

1
Q

another name for spore

A

conidia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

tichopytin made of
describe each componenet

A

galactomannan peptide
crude ag of dermatophytes
-cho componenet is immediate response
-peptide is delayed response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Dermatophyte test that is red in color shows

A

dermatophyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ring worm of scalp Tineacapitis causative agent

A

M. Canis (black dot ring worm)- dermatophyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cataneous fungi- malassezia furfur
patho and morphology and epidem

A

aka tinea cersicolor
morphology: short unbranched hyphy sphegetti and meatballs
patho: depifment or hyperpigment
epidem: world wide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cutaneous fungi
morphology
epidemiology
pathogenicity
identification

A

aka tinea nigra
morphology: dimorphic yeast and mold grow in salt
epidemiology : tropical
pathogenicity : brown lesions
identification: KOH and microsopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pediculosis?

A

caused by pediculus hamanus or lice

sucks blood

connects to hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are they
where are they found

A

bizzozero
found in the spinosum
desmosomes that connects cytoplasmic processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

basale
production:
mitotically active/inactive:
cell junctions:
cell shape:

spinosum
production:
mitotically active/inactive:
cell junctions:
cell shape:

A

basale
production: vit d
mitotically active/inactive: active
cell junctions: hemi and desmosome
cell shape: cuboidal to columnar

spinosum
production: vit d
mitotically active/inactive: inactive
cell junctions: desmosomes
cytoplasmic spines
cell shape: cuboidal to squamous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

psarisis happens due to what

A

basale rapid proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

granulosum
thickness:
cell type:
nuclei?

corneum
thickness:
cell type:
nuclei?

A

granulosum
cell amount: 1 - 3 layers
cell type: squamous cell
nuclei? yes

corneum
thickness: karatinized multiple cells
cell type: squamous
nuclei? no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

the follow can be seen in light microscopy or Electron microscopy

Basal Lamina

reticular lamina

basement membrane

A

EM
-basal lamina
-reticular lamina

light
basement membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

name two parts of dermis and differentiate them

A

Papillary
-loos connective tissue
-more cells
-ground substance
-thin collagen 1 and 3
thin elstic fibers

Reticular
-dense irregular connective tissue
-lee cellular
- closely packed fiber bundles
thick collagen 1
- thick elastic fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is this and where are they located

A

langer lines
cut perpendicular so faster healing , fiber arrangement of dermis
dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are these and where are they located

A

keratohyaline granules (blue)

-they give kerotized feature of stratum
-mostly found in granulosum

lamella bodies (red)
-produce water barrier
-located between granulosum and corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is this and its locations

A

hemidesmosomes
-what they do : tether keratinocytes to basal lamina
-where they are: basale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is this and its locations

A

desmosome
-what they do : tether keratinocytes together
-where they are: spinosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is this
red
blue
where are they derived

A

red melanocyte - derived from nueral crest
melanocyte granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what cell and what are the rod shapped things
where is this cell located

A

langerhan
-APC
-Spinosum

rod
- birbeck ganules that is made by lectin langerin
-they can internalize and degrade HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Merkel cell
what is it?
derived from ?
abundant where?
layer of skin?

A

Merkel cell
what is it? cell for sensation tactile
derived from ? ectoderm
abundant where? finger tips
layer of skin? basal

synapse with pseudounipolar nuerons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what is the blue and what cell

A

cytoplasmic processes of
langerhan
-APC
-Spinosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is this and where is it located

A

pacinian corpuscle
for deep pressure vibrations
located at bottom of dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is this and where is it located

A

meissner corpuscle tactile for tactile
upper dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

memorize

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

memorize …
this is part of what kind of gland

A

eccrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

associated with staph. aureus or streptococcus pyogene

-tsst1
-stss
-nonbollous impetigo
-necrotizing facitis
-local infecion
-spreading infection
-protein A
- protein M
-spe
-acute rheumatic fever
-type 2 necrotizing fascitis
-type 1

A

-tsst1 - s. aureus
-stss - step. pyrogen secondary to spe M prtotein
-nonbollous - strep py
-necrotizing facitis -strep py
-local infecion - s. aureus
-spreading infection - strep py
-protein A - s. aureus binds to Fc of IgG
- protein M - strep py… bind to cell stop phago cytosis
-spe - strep
-acute rheumatic fever - strep
-type 2 necrotizing fascitis - strep
-type 1. staph aur. and mixed anerobic and aerobic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

what is munro micro abscesses located and with which dz

A

epidermis and dermal infiltrates

psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

clumping factor vs coagulase

A

clumping
-cell wall protein binds firinogen and convert to fibrin for aggregation

coagulase
binds to prothrombin and converts it to fibrinogen to clot and avoid immune
-free protein
-tissue distruction
ex: hyaluronidase catase etc
-staphylokinase (fibrinolysin) : dissolves clot
penicillinase

31
Q

what dz

fishlike staining with immunofluorecsence IGG immunoglobulins around epidermal cell

A

pemphigus vulgaris

faccid bullae

located oral and trunk

suprabasal with basal intact

32
Q

what is propionibacterium

A

it causes actne pleomorphic aerotolerant anaerobe
folliculitis boil carbuncle

33
Q

non inflammatory acne
inflammatory acne

A

non inflammatory acne
-microcomedome (black and white heads)

inflammatory acne - follicular contents repture to dermis
-papule
-pustules
-nodule

34
Q

folliculitis

furuncles vs carbuncle
what causes it

which one is associated with hot tub

A

-s aureus majority
-p. aeruginosa G -
*** associated with hot tub)

furuncle is boil enlarge folliculitis carbuncle is muttiple hair follicles (dermis and sub)

35
Q

cause of gas gangreen?
another name
type of toxin released

A

myonecrosis

  • clostridium perfringens (anerobic)
    -spor forming
    g +
    anaerobic bacillus
    alpha toxin
    phospholipase c a leithinase
    lyse of cells
    increase entropy of heart
    histamine release
36
Q

erythema nodosum is a type of what

A

panniculitis
inflammation of fat
unknown cause but can be drugs infection sarcoidosis ulcerative colisitis
malagnancy

37
Q

biopsy shows muscle necrosis and gram variable and manifest of bronze, clear read blue bumps in three days of innoculation

A

myonecrosis or ganggreen

38
Q

blepharo conj is what type of infection and what pathogen causes it

A

it is a pyrogenic
caused by staph

39
Q

transient rapid rash with raised papules to erythematous plaque

how long does it take to form

A

urticaria (hives) fides within a day and happens within hours

40
Q

red papules and vescicles oozing and crusted skin lesions

spongiotic dermatitis eosinophils may be present

A

eczematous dermatitis

41
Q

types of eczematous dermatitis

how long does it take to form

A

atopic type 1 HSR asthma related or allerges

allergic contact dermatitis
type vour hyper sensitivity poison ivy and other agents nickle etc
happens 48 to 72 hours of contact and stays for 2-4 weeks

drug

photoexzematous

primary irritant dermatitis

42
Q

macules papules vesicles and bullae target lesions symetrical distribution on extremeties ….. how long does it take to form

A

erythema multiforme

2 weeks to a monthand goes away after a few weeks
caused by infection and druvs
self limited

interface dermatitis is milder form

43
Q

immuno fluorescence shows linear pattern immunoglobulin and compliment at basment membrane. dermo epidermal junction

A

bullous pemphigoid

tense bullae

IGG against BPAG 1 and 2 that causesamage to hemidesmosomes and release of basal layer from basement membrane

44
Q

what is stevens johson and what is it a subtype of

when does sx occur

worst case of this

A

subtype of erythema multiforme
-associated with drug exposure (anticonvulsant or sulfonamides)

-sx ocurr 2 weeks to 30 days

-involves oral and other mucosa
conjuctiva

-worst case is toxic epidermal nevrosis skin following off and causes fluid loss risk of infection

45
Q

pink/salmos colored plaques covered with loose silvery scales ( elbow knees scalp and soles of feet)

risk for …..
what other sx…

A

psarosis - hyper proliferation of kerotinocytes

risk for artharitis, heat attack and strok

other sx are nail changes

munro micro abscesses in epidermis and dermal infiltrates

46
Q

what is actinic chieilosisi and what can it lead to

A

squamous cell carcinoma it is on lip

47
Q

pruritic urple polygonal plana papules and plaques symetric involvment of writs and elbows

when does it go away

A

lichen planus

goes away 1-2 years and can have oral lesions

type 4 hsr
may happen with herpatitis or drug exposure

48
Q

what is wickham striae and what dz is it associated with

A

leasions coered in reticulated or net like
lichen planus

49
Q

interface dermatitis is

A

between dermis and epidermis angulated inflammation with apoptotic bodies part of lichen planus

50
Q

what is lichen simplex chronicus

A

thicked epidermius
raised erythematous scaly
end result of many lesions

51
Q

what is panniculitis

A

type 4 hypersensitivity recation of fat self limiting
erythema nodosum is most common
tender nodules involving legs
sarcoidosis
ulcertie colitis drugs infection but most unknown

52
Q

impetigo is caused by what 2 things

Where is this located and what is formed

what type of skin infection

A
  1. coagulase postive staphylococci
  2. streptococall infection beta hemolytic

VERY CONTAGIOUS

vesicles sub corneal, nuetrophils beneath
honey covered crust

pyogenic

53
Q

folliculittis is what kind of infection

A

pyogenic

54
Q

what is a complication of pyogenic infection

A

lymphanitis

55
Q

what are koilocytes cells and what dz are they found with…
in what layer of cell…

A

verucae or warts in epidermis
epidermal hyperplasia

self limited and go away after 2 years NO MALIGNANT POTENTIAL

they are vacuolated cells found in the Granular layer

56
Q

Easily ruptured bullae
what disease
where is it found
pathology of dz
hsr?

A

pemphigus vulgaris

face scapl axilla trunk and oral lesions

supra basal - basal stays attatched to basal membrane

patho autoimmune destruction of desmosomes due to IgG agains desmoglein (type 2 HSR)

acantholosys of keratonocytes in spinosum causes supravasal bullae

57
Q

tesne bullae

patho

location

A

bullous pemphigoid

milder than pempigus

goin abdomen in elderly and oral

immune dsetruction of hemidesmosome due to igG antibodies agains BPAG1 BPAG 2 (hemidesmosome proteins)

subepidermal

BASAL LAYER DETATCHED FROM BASEMENT MEMBRANE

58
Q

dz associated with gluten sensitivity

patho

location

A

bullous dz

dermatitis herpetiformis

patho ig a at the tipes of dermal paillae causeing subepidermal vesicles

located at extensors surface like elbows knees back butt

59
Q

what is ichthyosis

A

fish scales due to desquamation ( exfoliation) inheritied

60
Q

what causes vertiligo
vs
cause of albinism

A

vertiligo
destcution of melocytes secondary to autoimmune

albinisms
looss of pigment due to mutation for ensyme tyrosinase which makes melanin

61
Q

melasma
what is
who is at risk

A

hyperpig macules on face due to pregnancy or birth control pills go away after prego

62
Q

ephelis
what is

A

freckels

63
Q

lentigo
what is
where is it
size

A

linear hyperplasia melanocytes

long think rete ridges

dont get darker

in basal layer
size is 5-10 mm

64
Q

morphology of malocytic nevus

morphology of dysplastic nevus

what nevus mistaken for melanoma

A

malanocytic 6 mm uniform pigment with defined borders

dysplastic : 6 mm macule or plaque irregular border irregular pig and target center (dark center)

blue nevus (present at birth)

65
Q

what is evolution of melanocytic nevus

A

normal

junction - pigmented macule not elavated

compound - pigment paule elevated

dermal 0 intradermal paule - pigment fades elevated

66
Q

melanocytes are in what layer of skin

A

basal

67
Q

what is dysplastic nevus syndrom

gene mutation

A

multiple nevi 100

irregular shape and color (target dark in the middle)

risk of maligment melanoma

cdkn2a

68
Q

usually location of squamous cell carcinoma

caused by

name its morphology

A

lower lip (actinic keratosis actinic cheilosisi)

caused by hpv

keratin perls

69
Q

nests of basaloid (deeply basophillic) cells surrounded by palisading nuclei

what par of the body is this usually located

gene

rate of metasis

A

basal cell carcinoma

lower eye lid or face

rodent ulce

slow

rate metases

ptch suppressor gene inactive

70
Q

is vertical or horizontal growth worse

what about vascularitity

what about nuclear atypia

A

vertical

no correlation with vasculature and nuclear atypia

71
Q

what does dermal elastosis mean and what dz does this happen with

A

damage to collagen in dermis

acinic keratosis or actinic cheilosisi cheilitis (premaligment tumor

72
Q

some volcano shapped noduels

whats in the center

A

keratin is in the center

keratoacanthoma

73
Q

ptch gene mutation causes what

A

gorlin syndrom

basal cell carcinomas in younger people pamar pits

74
Q

pautrier micro abscess associated with what dz

A

mycosis funoides

t cells cd 4 infiltrate epidermis and ermis to form thes micro abcess

can turn into t cell leukemia , sezary syndrom

BASIG q1 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions