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BASIG q1 > Exam 3 > Flashcards

Exam 3 Flashcards

1
Q

Basal lamina made of what and what type of collagen

A

Epithelial

4

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2
Q

Reticular lamina made from what and what type of collagen

A

CT type 3

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3
Q

Name the colors

A

Blue reticular lamina
Yellow basal lamina
Green epithelial lamina

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4
Q

ecm consist of

A

ground substance and fibers

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5
Q

ground substance contains what and what kind of charg

A

gags proteoglycans PGs and multi adhesive glycoproteins , negative blue on h& e

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6
Q

to stain ground substance what dye would you use and why

A

carbon rich so PAS or H & E blue cause negative charged

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7
Q

is fibers or ground substance for resisting compression

A

ground sub

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8
Q

S that wispy substance

A

Ground

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9
Q

What are the main things that make up CT

A

ECM and cells

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10
Q

What’s the solid and dotted line

A

Solid is elastic fiber dotted is collagen fiber

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11
Q

Fiber or fibril, which can be seen with TEM or and LM

A

Fiber is TEM and LM fibril is TEM only

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12
Q

Reticular lamina is made by

A

CT

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13
Q

Basal lamina is made by

A

Epithelium

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14
Q

Which tissue type and name forms a cross link fence shape

A

4 basal lamina

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15
Q

Hat is type 1 and 2 collagen types

A

1 is bone and tendon 2 is cartilage

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16
Q

What type forms triple helix bundle

A

Type 3

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17
Q

T E M label

A

T fibrils M fibrillin Eelastin

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18
Q

What is Marfan syndrome

A

Genetic disorder defective fribilin stretch marks hypermobil joints tall aortic aneurysms

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19
Q

Is wandering or fixed short lived

A

Wandering

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20
Q

What does the fibroblast do

A

Secretes and maintains constituents of ECM

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21
Q

What cell is it fixed or wandering

A

Fibroblast

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22
Q

What cell is it fixed or wandering what does it do

A

Fixed multicellular Adipocyte

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23
Q

What cell is it fixed or wandering

A

Mast cell , allergic reaction contains granules and gag anticoagulant

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24
Q

What cells is this and is it fixed or wandering

A

Macrophage fixed

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25
Q

What cell and is it fixed or wandering

A

Macrophage fixed

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26
Q

What cell secretes antibodies

A

Plasma cells

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27
Q

What cell is it fixed or wandering

A

Wandering plasma cell secretes antibodies and have lots of rough er

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28
Q

What cell is it wandering or fixed

A

Wandering plasma cells

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29
Q

What cell and what does it do

A

Stem cell differentiates into may cells

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30
Q

What the of connective tissue is mesenchym

A

Embryonic CT

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31
Q

What general connective tissue is where most immune responses happen

A

Loose ct

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32
Q

What type of ct in yellow marks

A

Loose

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33
Q

Name these ct

A

Dense irregular and dense regular

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34
Q

What cell secretes leptin

A

White fat

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35
Q

What kind of tissue

A

Brown fat

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36
Q

What type of tissue and what does it do

A

Reticular CT forms the Strom a of organs

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37
Q

What cell promotes growth

A

Mesenchym

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38
Q

Buffy coat has what cell

A

Luekocytes and platelets

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39
Q

What cells from blood make up exam

A

Plasma

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40
Q

What has the second least amount in the blood, plasma , Buffy , hematocrit

A

Hematocrit 45%

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41
Q

What can we sample to monitor tissue health

A

Plasma

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42
Q

What is the difference between plasma and serum

A

Plasma has coagulation and serum does not

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43
Q

List from least to most amount in blood: Platelets, erythrocytes, luekocytes

A

Luekocytes platelets and erythrocytes

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44
Q

What is polycythemia

A

Increase in RBc cells

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45
Q

What is Luekocytosis

A

Increase in WBC

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46
Q

What are the formed elements

A

The Buffy coat (platelets and luekocytes) and hematocrit

47
Q

What organs remove dead rbc

A

Spleen and liver

48
Q

Name the outer and inner of cell. What is the cell

A

Thrombocyte out hyalomere inner is granulomere

49
Q

What is a halo mere and what is it made of

A

Microtubles out of platelet or thrombocyt

50
Q

What is this cell

A

Thrombocyte

51
Q

What happens first degranulates of platelets or platelet aggregation

A

Degranulates

52
Q

Cell and function name granules

A

Neutrophil infection

53
Q

Cell and its function

A

Eosinophil worms and paracites

54
Q

Name cell and granules

A

Red arrow and yellow arrow is specific gran and purple arrow is azurophilic granules top cells is neutrophil bottoms is eosinophil

55
Q

Cell and name granule

A

Yellow is specific granule for basophils

56
Q

What cell and what does it do

A

Lymphocyte self recognition

57
Q

What is a monocyte and what does it doe and look like

A

Fat chapped c phagocytosis

58
Q

What are the yellow and red arrows

A

Yellow is hemopoeitic cord
Red is sinusoidal capillary

59
Q

Common myeloid spits into what

A

Colony forming units and then blasts and then mature cells

60
Q

Name each and which one had heterochromatin

A

Poly chromatic orthochromatic reticulocyte

61
Q
A
  1. Myoblast
  2. Metamyoblast
    3.band or stab cell
    Top is neutrophil bottom is eosinophil
62
Q

Nuetrophil eosinophil basophil name their specific granules

A

Nuetrophil: and-h oxidase lysozyme
Eosinophil : crystalloid body
Basophil: heparin histamine

63
Q

Name from top left to right

A

Orthocromatic , polychromatic , basophillic eythroblast , reticulocyte

64
Q

What is hemostasis

A

Physiological injured vessel

65
Q

What is thrombosis

A

Pathological non injured like heart attack

66
Q

What is epistaxis

A

Nose bleed

67
Q

What is hemoptysis

A

Coughing up blood

68
Q

What is hematamesisi

A

Vomiting blood

69
Q

Hematochezia

A

Blood in stool

70
Q

Hematuria

A

Blood in ruin

71
Q

What is von willebrand factor

A

For primary platelet plug

72
Q

Is primary or secondary cause epistaxis and bleeding of gums

A

Primary

73
Q

Primary hemostasis issue caused by what

A

Thrombocytopenia (low platelets) ; vit c deficiency

74
Q

What is ADP thrombin A2 or TXA2

A

Secreted for primary hemostasis for clothing

75
Q

GPllB-IIIa bind to what

A

Fibrinogen

76
Q

How does aspirin work

A

It prevents production of TXA2

77
Q

How does placid work

A

ADP receptor blocker

78
Q

If you inhibit GPII- III a what happens

A

You make a blood thinner

79
Q

What lab tests to assoc primary hemostasis I

A

CBS , platlete function , von willabrand function, vitamin c test

80
Q

Explain secondary hemostasis

A

Factor 3 activated factor 7. 7 activates thrombin to convert fibrinogen to fibrin soluble And then factor 13 cross link to stabilize fibrin

81
Q

What factors need ca and K to coagulate

A

2 7 9 10

82
Q

What is proteins C and S

A

ANTI coag need K and Ca

83
Q

what activated factor 13

A

Thrombin

84
Q

How does Coumadin and warfarin work

A

K antagonist

85
Q

Explain fibrinolysis

A
86
Q

What is urokinase … what is strepto kinase

A

Plasminogen thatat fibrin lyses created by bacteria

87
Q

What does PTT and PT test for

A

PT is extrinsic factors 7 10 5 von prothrombin willebrand dz fibrogen… ptt is intrinsic 5,8, 9, 10,11,12

88
Q

What factors if vit k deficient pt or ptt prolong

A

2 7 9 10 , pt prolong

89
Q

Hemophilia is what kind of genetic disorder what pt or ptt prolong what factor causes

A

Ptt prolong x recessive 8

90
Q

What is ATIII

A

Natural coagulant

91
Q

What is heparin

A

Natural coag

92
Q

Where do thrombi formed in the veins go

A

Right heart to the lungs

93
Q

Where do thrombi formed in the arterial go

A

Systemic

94
Q

What is virchows triad

A

Endothelial injury
Abnormal blood flow
Hypercoagulability

95
Q

What cause intact vessel blood clot

A

Virchows triad . Injured endothelial , abn blood flow, hyper coag

96
Q

What factor comes with genetic hyper coag

A

5

97
Q

Leiden dz

A

Factor 5 missence , causes resistance to 2 digestion of protein c ,causes dot

98
Q

What is antiphospholipid syndrome

A

Auto immune causes stroke MI

99
Q

How does covid coag work

A

Increase in d dimer

100
Q

Lines of zhan

A

Caused by alt platelets no fibrin shows thrombosisi

101
Q

What is a mural thrombus and why is it so important

A

Common reason for system emboli. Thrombus in the heart changer

102
Q

What is phlebothrobosis

A

Vein clot

103
Q

What test for dot

A

D dimmer

104
Q

What is thrombophlebitis

A

Embolus that comes off blood clot

105
Q

Dot causes what

A

P[ulmonary embolism saddle embolus (block pulmonary art)

106
Q

What is atheroemboli

A

Spontaneous from ulcerated plaques following angioplasty, can happen to retina

107
Q

What can occur after Angie pasty

A

Atheroemboli

108
Q

Embolus in retina

A

CRAO

109
Q

Exogenous air vs endogenous air

A

Exogenous is for obstetrics and pneumonia thorax, endogenous is secondary to subadivers

110
Q

What organs do white anemic infarctions

A

Kidney heart and spleen

111
Q

Organs for hemorrhagic infarcts

A

Intestines and lungs

112
Q

Patience with thrombocytopenia are at risk for

A

Bleeding

113
Q

Facto v Leiden induces

A

Hypercoagulable state

BASIG q1 (11 decks)

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