Exam 6 Flashcards
What are CNS depressants used to treat?
Relax
- pain, insomnia, relive anxiety, induce relaxation, preform surgical procedures, treat muscle spams, manage psychoses and control epilepsy
What is the mechanism of action of CNS Depressants?
- reduce CNS overactivity
What are benzodiazepines used to treat?
- anxiety, alcohol withdrawal, insomnia, muscle spasms
What are the contraindications/ interactions of taking benzodiazepines?
NAG, CNSD, GFJ
- narrow angle glaucoma
- dont mix w/ other CNS depressants and alcohol
- don’t drink grapefruit juice
What are the four different categories of CNS depressants?
Benzo, H, Bar, MR
- benzodiazepines
- hypnotics
- barbiturates
- muscle relaxers
What is the FDA BBW for benzodiazepines?
RFA, PD, DCW/BOO
- risk for abuse
- physical dependence
- dont combine w/ other benzo’s or opioids
What are the adverse effects of taking benzodiazepines?
HYPO, C, SS, A, N/V, DM
- Hypotension
- confusion
- slurred speech
- ataxia
- nausea
- vomiting
- dry mouth
What should the nurse understand before administering benzodiazepine?
Paradoxical and rebound
- Paradoxical excitation causing hyperactivity and aggressive behavior may occur in all all ages
- rebound disinhibition may occur in older adults after tapering
- rebound insomnia may occur if abruptly stopped
What should the nurse educate the patient on before taking benzodiazepines?
WO, TWF, CPS, DS/DD
- wean off to stop
- take with food to avoid GI upset
- change positions slowly to prevent falls
- do both skip doses or double dose
what is the antidote for benzodiazepines?
Flumazenil
What can flumazenil (antidote) cause?
- abruptly withdrawal including seizures in long term user
What is hypnotics used to treat?
- insomnia
What are the contraindications/ interactions of taking hypnotics?
SA, COPD, PCC, D, CNSD, B, AED
- sleep apnea
- COPD
- pregnancy category C
- decrease dose for women
- depression
- CNS depressants
- barbiturates
- anti epileptic drugs
What is the FDA BBW for hypnotics?
sw/ sd
- sleepwalking and sleep driving
What should the nurse understand before administering hypnotics?
TPTB, SW
- take prior to bedtime
- swallow whole do not destroy pill
What should the nurse educate the pt on when taking hypnotics?
DCW/HFF, DTA12, 7-8 HOURS
- dont combine w/ high fat foods
- dont take after 12am
- take only if 7-8 hours of sleep was acquired the prior night
What are the adverse effects of taking hypnotics?
ANGIO, ANA, WD, T/D
- angioedema
- anaphylaxis
- worsening depression
- Tolerance and dependence
What is the mechanism of action of taking barbiturates?
Raises the seizure threshold in the treat of epilepsy
What are the contraindications/ interactions of taking barbiturates?
P, IRFF, DTI, IWSM
- pregnancy
- increases risk for falls
- disrupt TI of other drugs
- interacts with several medication
What are the adverse effects of taking barbiturates?
LTI, D, VND, HYP, MB, DR
- low therapeutic index
- drowsiness
- vivid and nightmarish dreams
- hypotension
- mild bradycardia
- decreased respirations
What should the nurse understand before administering barbiturates?
- give lowest effective dose unless used for epilepsy
What is the therapeutic blood level for phenobarbital?
10- 40 mcg/ mL
What can be used to treat barbiturates overdose?
AC, FD, IVF
- activated charcoal
- forced diuresis
- IV fluids
What should the nurse educate the pt on when taking barbiturates?
- women of reproductive years should use an additional method of BC