Exam 5 graded quiz 2024 Flashcards
In homestatic regulation, which mechanism receives information and processes it to be decided on a comand
control center
Where does a pro hormone undergo further processing prior to packaging into a secretory granule
Golgi
What is an example of a short, negative feedback loop
- Thryrotropin release hormone = thyrotropin releasing hormone
- IGF 1 = growth hormone
- Cortisol = ACTH
- GH = Growth hormone relasing hormone
GH = growth hormone releasing hormone
If a hormone concentration result in 50% of the maximal response, what could have happened to a hormone receptor number on target cells
increased
For tyrosine kinase receptors, on which domain does the tyrosine kinase activity occur
- transmembrane domain
- nuclear domain
- intracellular domain
- extracellular domain
intracellular domain
Which cell type in the anterior pituitary synthesizes and releases prolactin
- somatoptroph
- corticotroph
- thyrotroph
- lactotroph
somatotroph
What is removed from ADH or oxytocin as the hormone travels down the axon to the posterior pituitary
neurophysin
How does growth hormone achieve its indirect anabolic actions
- cortisol
- somatostain
- GnRH
- IGF-1
- IGF-2
through IGF-1 and IGF-2
What effect will low dietary iodide have on the activity of the Na/iodide symporter in the thyroid gland
stimulates
Which enzyme is down regulated in sick uethyroid syndrome, resulting in low T3
5’ deiodinase
If the disorder is in the pituitary in hyperthyroidism, what is the expectation for ciruclating levels of TSH
high TSH
Norepinephrine is the catecholamine primarly released from the sympathetic nerve terminals and brain. true or false
true
What effects do exogenous steriods have on ACTH production and relase
inhibit ACHT
What is a common adrenal cortex dysfunction to affect older dogs
- addisons disease
- hyperaldesteronism
- Pituitary dependent hyperadrenalcoritcism
- Pars intermedia dysfunctin
pituitary dependent hyperadrenocortism
in the pacreatic islets, what cell type is distibuted around the outer rim and produces glucagon?
alpha cells
Which tissue is dependent on insulin to transport glucose
- liver
- muscle
- brain
- intestine
muscle
What happens to glucose upon it entry into pancreatic beta cells
Immediatly phosphorylated
Which adipose tiisue hormone is associated with improved insulin sensitivity
Adiponectin
What will inhibit glucagon secretion
glucose
Where does insulin promote glycogen formation
muscle and liver
For which mineral is intestinal absoprtion fairly constant
Phosphate
What disorder is caused by increased phopshate in blood, which will precpiptate calcium and lead to hypocalcemia
- Secondary hyperparathyroidism
- primary hyperthyroidism
- ostemomalacia
- hypoparathyroidism
secondary hyperparathyrodisim
What change occurs in melatonin with age and puberty
decreases
What would be the precursor for a prostanoid such as PGF3
Eicosapentaenoic acid
If ionized plasma calcium concentration falls, what events will be expected to start happening
- vitamin D synthesis would be stimulated by PTH
- bone reabsorption would be inhibited
- Parathyroid hormone
would be relased - renal reabsoprtion of calcium would be inhibited
- vitamin D synthesis would be stimulated by PTH
- Parathyroid hormone would be relased
