Exam 4 Material (Drugs Lecture)

Question 1

What is a drug that blocks a neurotransmitter?

Answer 1

Antagonist

Question 2

What is a drug that increases a neurotransmitter’s effects?

Answer 2

Agonist

Question 3

What is the ability of a drug to bind to a receptor (ex: just b/c the key fits doesn’t mean it will unlock the lock)?

Answer 3

Affinity

Question 4

What is the ability of a drug to activate a receptor (ex: can turn the lock and open the lock)?

Answer 4

Efficacy

Question 5

What do agonists have?

Answer 5

Affinity and efficacy

Question 6

What do antagonists have?

Answer 6

Affinity, but no efficacy

Question 7

What do drugs of abuse have in common?

Answer 7

Affect dopamine (and NE) synapses (in NAc)

Question 8

What drugs increases excitement, alertness, motor activity, and mood (amphetamine and cocaine increase the availability of dopamine/inhibit the dopamine transporter, ritalin blocks the reuptake of dopamine but in a more gradual and more controlled rate, nicotine simulates one type of acetylcholine receptor known as the nicotinic receptor)?

Answer 8

Stimulant drugs

Question 9

What are drugs that are derived from the opium poppy (decrease sensitivity to pain and increase relaxation/attach to endorphin receptors, THC attaches to cannabinoid receptors throughout the brain/inhibit the release of glutamate and GABA)?

Answer 9

Opiates

Question 10

What drugs cause distorted perception (resembles serotonin in their molecular shape, stimulate serotonin type 2A receptors/5HT2A)?

Answer 10

Hallucinogens