Exam 4 - Diabetes Mellitus (DM) Flashcards
Causal factor for type 1 DM
- Exact cause unknown
- Genetic predisposition, environmental triggering event, T-lymphocyte-mediated hypersensitivity reaction against some beta cell antigen
- Immune system destroys islet cells in pancreas
- Over-production of glucagon –> gycogenolysis & gluconeogenesis
- Glucose levels rise –> “3 P’s” – polyuria, polydipsia, polyphagia
Very-basically—What happens in diabetic ketoacidosis? Look at Laura’s slides.
- When body doesn’t have enough insulin, FFA’s (free fatty acids) are broken down as an alternate fuel
- Process produces an excess of ketones (toxic acids), leading to metabolic acidosis
S/S of diabetic ketoacidosis
- “3 P’s” – polyuria, polydipsia, polyphagia (classic symptoms of hyperglycemia)
- Hyperglycemia
- Dehydration
- Ketosis
- Acidosis (metabolic)
- Ketone/sugar levels in urine
- Fruity (acetone) breath
- Kussmaul respirations
- (Can happen in T2 in extreme situations, but typically seen in T1 – especially with onset of diabetes or infection)
Basic definition of type 2 DM? (for example: is there an absolute absence of insulin or a
resistance to insulin—simple information like this!)
- A combination of beta cell dysfunction and insulin resistance
Important risk factors for type 2 DM. Which 2 are most important per Laura?
- *** Obesity
- *** Family history
- Aging
- Sedentary lifestyle
How does obesity increase the risk for developing type 2 DM?
- Insulin resistance in fat cells leads to reduced glucose intake
- Overweight people also require more insulin
Very basically—how do the oral medications for type 2 DM work? Are they oral insulin or do
they help the cells release insulin?
- Stimulate the cell release of insulin
- Inhibits the release of glucose
- Slows the breakdown of starches
Be able to recognize the signs & symptoms of hypoglycemia. What are some general causes?
- Headache
- Irritable
- Hunger
- Weakness/fatigue
- Shaking
- Sweating
- Anxious
- Dizziness
- Tachycardia
- Impaired vision
Causes:
- Insufficient food intake
- Too much exercise
- Too much insulin
Be able to distinguish between the signs & symptoms of diabetic ketoacidosis & hyperglycemic hyperosmolar nonketotic syndrome
DKA: T1 (or T2 in severe distress), glucose > 300, high ketones, pH acidotic, N/V ab pain diarrhea
HHNS: T2, glucose > 600, no ketones, normal pH, no GI symptoms
Be able to recognize the 3 P’s of diabetes in a question/scenario
- Polydipsia
- Polyuria
- Polyphagia
Be able to distinguish between hypoglycemia, the Somogyi effect & the dawn phenomenon
- Hypoglycemia: low blood sugar at any time
- Somogyi effect: insulin peaks in middle of night, hyperglycemia in morning. Treat with DECREASE of BEDTIME insulin dose (vs treating with more insulin in a.m.)
- Dawn phenomenon: high blood sugar in the morning related to GH release at night, encourage protein snack at bedtime (limit carbs)
A client is receiving NPH insulin 20 units subcutaneously at 0700 hours daily. At 1500 hours, the nurse finds the client apparently asleep. How would the nurse know whether the client was having a hypoglycemic reaction?
- Feel the client and bed for dampness.
- Observe the client for Kussmaul respirations.
- Smell the client’s breath for acetone color.
- Note if the client is incontinent of urine.
- Feel the client and bed for dampness
Rationale: When clients are sleeping, the only observable sign of hypoglycemia is diaphoresis. Kussmaul breathing and acetone odor to breath are indicative of hyperglycemia. Incontinence is not associated with hypoglycemia and polyuria may be associated hyperglycemia.
A client is found to be comatose and hypoglycemic with a blood glucose level of 50 mg/dL. What nursing action is implemented first?
- Infuse 1000 mL of D5W over a 12-hour period.
- Administer 50% glucose intravenously.
- Check the client’s urine for the presence of sugar and acetone.
- Encourage the client to drink orange juice with added sugar.
- Administer 50% glucose intravenously
Rationale: The unconscious, hypoglycemic client needs immediate treatment with 50% intravenous glucose (highly concentrated). Administering 1000 mL of D5W over 12 hours does not provide enough glucose to treat the problem. Trying to give oral fluids to an unconscious client should never be done because it increases the risk for aspiration. Urine sugar does not need to be evaluated if the serum blood glucose is available.
What will the nurse teach the client with diabetes regarding exercise in the treatment program? Select all that apply.
- During exercise the body will use carbohydrates for energy production, which in turn will decrease the need for insulin.
- With an increase in activity, the body will use more carbohydrates; therefore, more insulin will be required.
- Exercise increases the HDL and decreases the chance of stroke and heart disease.
- The increase in activity results in an increase in the use of insulin; therefore, the client should decrease his or her carbohydrate intake.
- Exercise will improve pancreatic circulation and stimulate the islets of Langerhans to increase the production of intrinsic insulin.
1, 3
(During exercise the body will use carbohydrates for energy production, which in turn will decrease the need for insulin; Exercise increases the HDL and decreases the chance of stroke and heart disease.)
As carbohydrates are used for energy, insulin needs decrease. Therefore during exercise, carbohydrate intake should be increased to cover the increased energy requirements. The beneficial effects of regular exercise may result in a decreased need for diabetic medications in order to reach target blood glucose levels. Furthermore, it may help to reduce triglycerides, LDL cholesterol levels, increase HDLs, reduce blood pressure, and improve circulation. Increased HDLs have been associated with a decrease in Syndrome X (Metabolic Syndrome).
What is characteristic of hypoglycemia that should alert the nurse to an early insulin reaction?
- Diaphoresis
- Drowsiness
- Severe thirst
- Coma
- Diaphoresis
Diaphoresis and a shaky feeling (nervousness) are early signs of hypoglycemia. Severe thirst is a sign of hyperglycemia, whereas drowsiness and coma are late symptoms of hypoglycemia.