Exam 3 - Neurologic Disorders Flashcards
Types of concussion & be able to recognize the type given its description
Mild Concussion (Grades I-III)
- Temporary axonal disturbances causing attention and memory deficits but no loss of consciousness
- Grade I – confusion, disorientation, and momentary amnesia
- Grade II – momentary confusion and retrograde amnesia
- Grade III – confusion with retrograde and anterograde amnesia
Classic Cerebral Concussion
- Grade IV:
o Disconnection of cerebral systems from the brainstem and reticular activating system
o Physiologic and neurologic dysfunction without substantial anatomic disruption
o Loss of consciousness (<6 hours)
o Anterograde and retrograde amnesia
o Uncomplicated (no focal injury) or complicated (focal)
Pathophysiology & causes/triggers including level of spinal cord injury of autonomic dysreflexia
- Massive, uncompensated cardiovascular response to stimulation of the sympathetic nervous system
- Stimulation of the sensory receptors below the level of the cord lesion - injury T-6 or higher
- Causes:
o Restrictive clothing
o Pressure ulcer
o Full bladder or UTI
o Fecal impaction
Physical assessment & clinical findings for arteriovenous malformation (AVM)
- (What it is: Vein and artery connect in unnatural place, lack capillary)
- Causes bruit (auscultating)
- Typically present before 40 years of age and affect men and women equally
- Slowly progressive neurologic deficits
- Intracerebral and subarachnoid hemorrhage
- Seizures
- Headache – often severe, c/o throbbing and synchronous w/heartbeat
- Other focal symptoms depend on location of lesion and visual symptoms (i.e., diplopia and hemianopia), hemiparesis, mental deterioration, and speech deficits
- Definitive diagnosis often is obtained through cerebral angiography
Disorders that cause a positive Kernig & Brudzinski sign
- Encephalitis or meningitis – presence of nuchal rigidity and a positive Kernig’s sign or Brudzinski’s sign
- Subarachnoid hemorrhage – blood escapes from defective or injured vasculature into the subarachnoid space
Most common primary central nervous system tumor
- Astrocytoma – largely tumors of adults but still the leading primary brain tumor in children
Pathophysiology of multiple sclerosis
- MS is chronic, progressive, noncontagious degenerative disease of the CNS characterized by inflammation and selective destruction of CNS myelin
- Damage occurs in diffuse patches throughout the nervous system and slows or stops nerve impulses
Coup injury
- Injury directly below the point of impact
- Most contusions result from a blunt blow to the head that causes the brain to make sudden impact with the skull
- The initial area the brain impacts with the skull is referred to as the coup
Contrecoup/countercoup injury
- Injury on the pole opposite the site of impact
- After the brain has initial impact with the skull, the brain then rebounds and impacts with the opposite side of the skull, causing another area of damage referred to as the countercoup
Pathophysiology of myasthenia gravis
- Chronic autoimmune disease
- IgG antibody produced against acetylcholine receptors – leads to disruption at neuromuscular junction
- Disruption causes weakness of the voluntary skeletal muscles because nerves aren’t stimulated as much
- Muscle weakness typically increases during periods of activity and improves after periods of rest
- Muscles that control breathing and neck and limb movements may be affected
- Exact trigger for autoimmune response is unclear but the thymus gland is thought to play a role
Client teaching about the prevention of myasthenic and cholinergic crises in myasthenia gravis
- The priority for both is to maintain adequate respiratory function
- M: caused by undermedication; C: caused by overmedication
- M: hold meds (increase secretions), remove secretions
- C: drugs withheld while on vent, Atropine given and repeated if necessary, causes muscle twitching, observe for thickened secretions, can’t cough
- Tensilon is test administered - muscles get stronger with M crisis
Pathophysiology of & risk factors for Guillain-Barré syndrome
- Acquired inflammatory disease causing demyelination of the peripheral nerves with relative sparing of axons
- Preceded by a bacterial or viral illness
- Immune system overreacts to the infection and destroys the myelin sheath
- Acute onset, ascending bilaterally (toes to head) weakness leading to motor paralysis, infectious neuronitis
- Humoral and cellular immunologic reaction
- Risk factors:
o Possibly autoimmune
o Association with immunizations
o Frequently preceded by mild respiratory or intestinal infection
“FASTG”
Stroke assessment
- F facial droop (cranial nerves) – show teeth or smile
Abnormal – one side of face does not move as well as the other side
- A arm drift (motor) – hold arms out, palms down and close eyes
Abnormal – one arm cannot be lifted or drifts down
- S speech – repeat phrase
Abnormal – wrong or inappropriate words or unable to speak (aphasia) caused by left hemispheric deficit; slurred words (dysarthria) caused by cranial nerve deficit
- T time last seen or known normal
Time is major determinant in what interventions may be effective
- G glucose
Blood glucose used to rule out hypoglycemia as a reversible cause of stroke-like symptoms
High priority assessment tool, especially in diabetic patients or those with other potential reasons to be hypoglycemic
Cavernous angioma
description
- Blood vessel malformation
- Large blood filled spaces (does not contain tissues of organ it inhabits)
- Slow blood flow
- Symptoms: seizures, headaches, hemorrhage or compression of surrounding brain tissue, weakness, numbness, double vision, visual disturbance, language difficulties
Capillary telangiectasia
description
- Small collection of abnormally dilated capillaries deep within otherwise normal brain tissue
Arteriovenous angioma
description
- Congenital tumor
- Consists of a tangle of coiled, usually dilated arteries and veins, islets of sclerosed brain tissue, and occasionally, cartilaginous cells
- Lesion may be distinguished by an intracranial bruit, found in pia mater
- May grow to project deeply into the brain, causing seizures and progressive hemiparesis