Exam #4 Flashcards
What is the basic function of a nephron?
Make urine
Where are the kidneys located
Retroperitoneal
Lie against posterior abdominal wall
What are the 2 different types of nephrons
Cortical nephron
Juxtamedullary nephron
85% of all nephrons
have SHORT nephron loops
Cortical nephrons
15% of all nephrons
have LONG nephron loops
juxtamedullary nephrons
Which nephron helps to maintain salinity gradient in medulla and helps to maintain water?
juxtamedullary nephrons
what are the components of a renal corpuscle?
glomerulus
glomerular (bowman) capsule
capsular space
what is the filtration membrane made of
fenestrated endothelium
basement membrane
podocytes with filtration slits
what are the types of cells that line the PCT
simple cuboidal epithelia
what is the main function of the PCT
reabsorption of all organic nutrients
what is the function of the juxtaglomerular apparatus
control afferent arteries
patch of slender epithelia cells at the end of the nephron loop ( beginning of DCT)
senses variations in flow or fluid composition
macula densa
what is the juxtaglomerular apparatus composed of
macula densa and JG cells
enlarged smooth muscle cells in afferent arteriole
when stimulated by the macula they dilate or constrict the arterioles
also contain renin
JG cells
JG cells contract to constrict afferent arterioles when GFR is
high
Macula densa relaxed afferent arterioles if GFR is
low
What does glomerular filtrate contain
organic nutrients
( sodium water and other ions)
What is GFR
amount of filtrate formed per min by the two kidneys combined
what are the 3 forces affecting glomerular filtration
glomerular hydrostatic pressure
osmotic pressure
capsular hydrostatic pressure
What are the two methods of autoregulation of the GFR
myogenic mechanism
tubuloglomerular feedback
seminal vesicles form what percentage of semen
60%
prostate gland forms what percentage of semen
30%
What is cryptorchidism
boys born with undescended testis