Exam 3 Vitamins Flashcards
Vitamin B12 function
cell division, RBC
Vitamin B12 deficiency
fatigue, megaloblastic anemia, pernicious anemia- lack of Intrinsic factor
Vitamin B12 sources
animal products (MFP, egg, milk
Vitamin C: ascorbic acid funciton
function: antioxidant, collagen synthesis
Antioxidant
• Reducing agent
• Reverse oxidation by donating electrons and hydrogen ions
decrease free radicals and reactive oxygen species (oxygen
components that are highly oxidative, i.e. OH., O2-, H2O2, HO2.)
• I.e. attack lipids and protein in membranes such as oxidizing LDL
2. Collagen synthesis
• Hydroxylation reactions of proline and lysine are necessary for
collagen formation
Vitamin C: ascorbic acid deficiency
Deficiency: scurvy (bleeding gums)
Vitamin C: ascorbic acid sources
Sources: citrus, pepper, green leafy, veggies, potatoes
papaya, oranges, orange juice, cantaloupe, cauliflower,
broccoli, brussel sprouts, green peppers, grapefruit,
grapefruit juice, kale, lemons, strawberries
Vitamin C name
Vitamin C: ascorbic acid
VB1 (thiamin)
Function
Function: energy production
- Energy Transformation
• TDP (TPP) functions as coenzyme in catalyzing decarboxylation of
pyruvate and α-ketoglutarate
• pyruvate to acetyl CoA (pyruvate dehydrogenase complex)
• α-ketoglutarate to succinyl CoA
• Both of these reactions are important for release of energy from
food in formation of ATP - NADPH and pentose
• TDP needed for transketolase reaction which forms pentoses
• Pentoses used in synthesis of nucleic acids for RNA/DNA - Nerve Conduction
VB1 (thiamin) deficiency
Def: beriberi )weakness, wasting)
Sources: pork, grains, enriched grains
Ribo, folate enriched grains have to be added mineral: iron
VB1 (thiamin) sources
Sources: pork, grains, enriched grains
Ribo, folate enriched grains have to be added mineral: iron
Folic acid (folate) function
function: cell division, RBCs
Folic acid (folate) deficiency
megaloblastic anemia (fatigue)
Folic acid (folate) sources
green leafy veggies, citrus, enriched grains, beans
Pantothenic acid function
energy production
Pantothenic acid deficiency
burning feet, fatigue, spasms
Pantothenic acid sources
everywhere: meat, fish, poultry, legumes, grains, veggies
Pantothenic acid part of what molecule
acetyl CoA, center of all metabolism, Krebs cycle, CoA
VB2 Riboflavin is the coenzyme form of?
Coenzyme form is Flavin adenine dinucleotide (FADH2) (start electron transport chain to make ATP)
VB2 Riboflavin function
Function: energy production
VB2 Riboflavin deficiency
Def: oral lesions
VB2 Riboflavin sources
Sources: meat, fish, poultry, dairy, grains, enriched grains
Niacin: NADH, NAD function
Function: energy production
Niacin: NADH, NAD deficiency
Deficiency: pellagra (4Ds- diarrhea, dermatitis, dementia, death)
Niacin: NADH, NAD sources
Sources: meat, fish, poultry, grains, enriched grains, conversion from tryptophan
Biotin fucntion
funccton : fat synthesis
biotin deficiency
def: egg white injury, (fatigue, weakness). avidin protein binds to biotin
biotin sources
sources: egg yolk, meat, fish, poultry, legumes, bananas
Vitamin B6
VB6: pyridoxine
VB6: pyridoxine function
Function: amino acid metabolism, heme synthesis