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Clin Med Lab Med > Exam #3: Thyroid/Parathyroid > Flashcards

Exam #3: Thyroid/Parathyroid Flashcards

1
Q

Where does conversion of T4 → T3 occur?

A

LIVER

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2
Q

What two thyroid Abs are indicative of Hashimoto’s?

A

+TPO Ab

+TgAb

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3
Q

What condition involves:
+TPO Ab
+TgAb

A

Hashimoto’s

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4
Q

What thyroid Ab is indicative of Graves’ Disease?

A

+TRAb

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5
Q

What condition involves:

+TRAb

A

Graves’ Disease

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6
Q

What condition are each of these tests used to evaluate:

  • RAIU?
  • US?
  • FNA?
A
  • RAIU = hyperthyroidism
  • US = nodules
  • FNA = thyroid CA
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7
Q

What are four possible causes of ENDOgenous hyperthyroidism?

A
  • Graves’ Disease
  • Toxic MNG
  • Toxic Adenoma
  • Thyroiditis
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8
Q

What are two possible causes of EXOgenous hyperthyroidism?

A

Iatrogenic

  • Overreplacement for hypothyroidism
  • Suppressive = Thyroid CA
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9
Q

What condition involves heat tolerance, anxiety, tremor, diarrhea, heart palpitations?

A

Hyperthyroidism

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10
Q

On RAIU, diffuse and HIGH is indicative of?

A

Graves’ Disease

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11
Q

On RAIU, diffuse and LOW is indicative of (2)?

A
  • Thyroiditis

- T3 Thyrotoxicosis

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12
Q

On RAIU, focal is indicative of (2)?

A
  • Toxic MNG

- Toxic adenoma

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13
Q

If Subacute Thyroiditis is suspected, what test should be obtained?

A

ESR/CRP

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14
Q

For all Hyperthyroidism etiologies, TSH levels are?

A

TSH = LOW

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15
Q

On RAIU, focal, hyperfunctioning/hot is indicative of?

A

Benign

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16
Q

On RAIU, focal, hypofunctioning/cold is indicative of?

A

Possible malignancy

17
Q

What are the four recommended treatments for Hyperthyroidism?

A
  • BB
  • Methimazole (vs. PTU)
  • Radioactive iodine ablation
  • Surgery
18
Q

If Central Hypothyroidism is suspected, what test should be ordered?

A

Pituitary MRI

19
Q

What condition presents with fatigue, depression, weight gain?

A

Hypothyroidism

20
Q

What is the recommended treatment for Hypothyroidism?

A

Levothyroxine (Synthroid)

21
Q

What four things should be considered with use of Levothyroxine (Synthroid)?

A
  • Weight-based
  • Lower dose if 60+ years OR cardiac concerns
  • Take on empty stomach one hour before breakfast
  • Caution that meds can interfere with absorption
22
Q

What two tests should be obtained for Thyroid Nodule?

A
  • TSH

- Thyroid US

23
Q

What are the four steps involved in diagnosis of a Thyroid Nodule?

A
  1. TSH and US
  2. IF TSH low, order RAIU
  3. Hot = nodule, Cold = possible malignancy
  4. If Cold, order FNA
24
Q

Low TSH + high Free T4 indicates?

A

Primary Hyperthyroidism

25
Q

High TSH + low Free T4 indicates?

A

Primary Hypothyroidism

26
Q

If TSH and Free T4 in same direction, what might this indicate?

A

Another cause

- Central (secondary vs. tertiary)

27
Q

If low TSH + low Free T4, what test should be obtained?

A

Pituitary MRI

Clin Med Lab Med (13 decks)

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