Exam #3: Rheumatology Flashcards
What condition involves malar rash, discoid rash, polyarthritis, mucosal ulcers, renal issues?
SLE
What three findings will be + with SLE?
+Anti-dsDNA (+ if acute)
+Anti-Sm (+ if acute OR chronic)
+ANA
What condition involves:
+Anti-dsDNA (+ if acute)
+Anti-Sm (+ if acute OR chronic)
+ANA
SLE
How can you differentiate acute vs. chronic SLE?
ACUTE: +Anti-dsDNA, +Anti-Sm
ACUTE OR CHRONIC: +Anti-Sm
What ANA subtype is associated with VTE?
Antiphospholipid Ab
- Antiphospholipid Syndrome
What condition involves morning stiffness 1+ hours; redness/swelling of PIP and MCPs (DIPs spared), ulnar deviation at MCPs?
RA
What joints are affected, and which are spared with RA?
- PIP and MCPs affected
- DIPs spared
What three findings will be + with RA?
+Anti-CCP (high specificity)
+/- RF (moderate specificity)
+ANA
What condition involves:
+Anti-CCP
RA
What condition involves speckled pattern on immunofluorescent stain?
RA
What condition involves sicca complex: fatigue, dry mouth/eyes, diffuse joint aching?
Sjogren Syndrome
What condition involves:
+Anti-Ro/SSA
+Anti-La/SSB
+ANA
Sjogren Syndrome
What three findings will be + with Sjogren Syndrome?
+Anti-Ro/SSA
+Anti-La/SSB
+ANA
What condition involves proximal aching/stiffness esp. in morning/prolonged sitting; subjective weakness, normal strength?
Polymyalgia Rheumatica (PMR)
What condition is improved with steroids, age 55+ years?
Polymyalgia Rheumatica (PMR)
What finding will be + if Polymyalgia Rheumatica (PMR)?
ESR
What condition presents with elevated ESR? What other condition might present with an elevated ESR?
Polymyalgia Rheumatica (PMR) - Also associated with Giant Cell Temporal Arteritis
What condition involves generalized arthralgias and myalgias, “foggy” mind; normal PE; NORMAL LABS?
Fibromyalgia
What condition involves low back pain, progressive stiffness (worse in morning and with rest, better with activity)?
Ankylosing Spondylitis (AS)
What condition involves bamboo spine, sacroiliitis; association with plantar fasciitis?
Ankylosing Spondylitis (AS)
What finding will be + with Ankylosing Spondylitis (AS)?
+HLA-b27
What condition involves:
+HLA-b27
Ankylosing Spondylitis (AS)
What condition involves CREST, and what does this stand for?
LIMITED Systemic Sclerosis
- Calcinosis
- Raynaud’s
- Esophageal dysfunction
- Sclerodatyly
- Telangiectasias
What two findings will be + with LIMITED Systemic Sclerosis?
+ACA
+ANA
