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Clin Med Lab Med > Exam #3: Rheumatology > Flashcards

Exam #3: Rheumatology Flashcards

1
Q

What condition involves malar rash, discoid rash, polyarthritis, mucosal ulcers, renal issues?

A

SLE

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2
Q

What three findings will be + with SLE?

A

+Anti-dsDNA (+ if acute)
+Anti-Sm (+ if acute OR chronic)
+ANA

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3
Q

What condition involves:
+Anti-dsDNA (+ if acute)
+Anti-Sm (+ if acute OR chronic)
+ANA

A

SLE

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4
Q

How can you differentiate acute vs. chronic SLE?

A

ACUTE: +Anti-dsDNA, +Anti-Sm

ACUTE OR CHRONIC: +Anti-Sm

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5
Q

What ANA subtype is associated with VTE?

A

Antiphospholipid Ab

- Antiphospholipid Syndrome

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6
Q

What condition involves morning stiffness 1+ hours; redness/swelling of PIP and MCPs (DIPs spared), ulnar deviation at MCPs?

A

RA

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7
Q

What joints are affected, and which are spared with RA?

A
  • PIP and MCPs affected

- DIPs spared

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8
Q

What three findings will be + with RA?

A

+Anti-CCP (high specificity)
+/- RF (moderate specificity)
+ANA

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9
Q

What condition involves:

+Anti-CCP

A

RA

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10
Q

What condition involves speckled pattern on immunofluorescent stain?

A

RA

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11
Q

What condition involves sicca complex: fatigue, dry mouth/eyes, diffuse joint aching?

A

Sjogren Syndrome

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12
Q

What condition involves:
+Anti-Ro/SSA
+Anti-La/SSB
+ANA

A

Sjogren Syndrome

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13
Q

What three findings will be + with Sjogren Syndrome?

A

+Anti-Ro/SSA
+Anti-La/SSB
+ANA

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14
Q

What condition involves proximal aching/stiffness esp. in morning/prolonged sitting; subjective weakness, normal strength?

A

Polymyalgia Rheumatica (PMR)

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15
Q

What condition is improved with steroids, age 55+ years?

A

Polymyalgia Rheumatica (PMR)

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16
Q

What finding will be + if Polymyalgia Rheumatica (PMR)?

A

ESR

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17
Q

What condition presents with elevated ESR? What other condition might present with an elevated ESR?

A 
Polymyalgia Rheumatica (PMR)
- Also associated with Giant Cell Temporal Arteritis
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18
Q

What condition involves generalized arthralgias and myalgias, “foggy” mind; normal PE; NORMAL LABS?

A

Fibromyalgia

19
Q

What condition involves low back pain, progressive stiffness (worse in morning and with rest, better with activity)?

A

Ankylosing Spondylitis (AS)

20
Q

What condition involves bamboo spine, sacroiliitis; association with plantar fasciitis?

A

Ankylosing Spondylitis (AS)

21
Q

What finding will be + with Ankylosing Spondylitis (AS)?

A

+HLA-b27

22
Q

What condition involves:

+HLA-b27

A

Ankylosing Spondylitis (AS)

23
Q

What condition involves CREST, and what does this stand for?

A

LIMITED Systemic Sclerosis

  • Calcinosis
  • Raynaud’s
  • Esophageal dysfunction
  • Sclerodatyly
  • Telangiectasias
24
Q

What two findings will be + with LIMITED Systemic Sclerosis?

A

+ACA

+ANA

25
Q

What condition involves:
+ACA
+ANA

A

LIMITED Systemic Sclerosis

26
Q

What two findings will be + with DIFFUSE Systemic Sclerosis?

A

+Anti-Scl-70 Ab

+ANA

27
Q

What condition involves:
+Anti-Scl-70 Ab
+ANA

A

DIFFUSE Systemic Sclerosis

28
Q

What three findings will be seen with Gout?

A
  • MSU
  • Negatively birefringent
  • Needle-shaped
29
Q

What three findings will be seen with Pseudogout?

A
  • CPPD
  • Positively birefringent
  • Rhomboid-shaped
30
Q

What condition involves MSU, negatively birefringent, needle-shaped?

A

Gout

31
Q

What condition involves CPPD, positively birefringent, rhomboid-shaped?

A

Pseudogout

32
Q

What is the most severe risk associated with an Arthrocentesis?

A

SEPTIC JOINT

33
Q

What test is used to evaluate joint effusion or inflammation?

A

Arthrocentesis

34
Q

What are four indications for performing an Arthrocentesis?

A
  • New onset/acute monoarthritis
  • Suspected crystal arthritis
  • Suspected infection/septic arthritis
  • Unexplained swelling
35
Q

What three characteristics are seen with NORMAL Joint (Synovial) Fluid?

A
  • Viscous
  • Clear (egg white consistency)
  • Acellular
36
Q

How can you differentiate inflammatory from Non-inflammatory joint?

A
  • Inflammatory = 2000+ WBCs

- Non-inflammatory = less than 2000 WBCs

37
Q

If joint fluid is opaque, what is this indicative of?

A

Septic joint

38
Q

If joint fluid is yellow, what is this indicative of (2)?

A
  • Inflammatory joint

- Non-inflammatory joint

39
Q

If joint fluid is yellow/green, what is this indicative of?

A

Septic joint

40
Q

If joint fluid has LOW viscosity, what is this indicative of?

A

Inflammatory joint

41
Q

A joint is _____ if 100,000 WBCs until proven otherwise?

A

SEPTIC

42
Q

Joint with 75+% neutrophils (PMNs) is indicative of?

A

Septic joint

43
Q

What type of joint presents with + culture?

A

Septic joint

Clin Med Lab Med (13 decks)

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