Exam 3 Part 2 Flashcards
How long does early Alzheimer’s last?
2 years
True or false: motor function is retained in early Alzheimer’s
True
How long does mid-stage Alzheimers last?
4-10 years
Stage of Alzheimer’s that has a negative impact on ADL and reliance on others, may experience wanderlust, sundowner syndrome, disorientation and confusion
Mid-stage
What are the symptoms of mid-stage Alzheimer’s?
More severe memory loss, increased loss of working memory, attention deficit, diminished vocabulary, conversation is empty/meaningless, loss of reading and writing, aggressiveness, outburst of anger, dramatic personality changes, inappropriate behavior, hallucination/delusion
Stage of Alzheimer’s where motor function is impacted, may become non-ambulatory, unresponsive, bedridden
Late stage Alzheimer’s
What are symptoms of late stage Alzheimer’s?
Memory, condition, expressive language deficits are profound, muteness, dysphagia, little/no memory, difficulty speaking and understanding simple sentences, difficulty recognizing others, need for assistance for ADL, difficulty chewing and swallowing
Dementia defined by degeneration of frontal and temporal lobe; includes Pick’s disease, progressive nonfluent aphasia, semantic dementia
Frontotemporal dementia
Slow reduction in verbal output
Progressive non-fluent aphasia
Progressive degeneration of frontal and temporal lobe
Pick’s disease
What are some symptoms of Pick’s disease?
Personality changes, antisocial and inappropriate behavior, memory loss in absence of language deficits
What is the neuropathology of Pick’s disease?
Pick bodies and ballooned neurons
Subcortical dementia; progressive terminal illness characterized by distinctive involuntary erratic body movements
Huntington’s disease
What are the symptoms of Huntington’s disease?
Changes in personality, cognition, language, and emotion
What is the neuropathology of Huntington’s disease?
Production of mutant Huntington protein that creates degeneration of basal ganglia, hippocampus, substantia nigra, and Purkinje cells of pons