Exam #3: Hypothalamus Flashcards
What is the general function of the hypothalamus?
Hypothalamus= general function is “homeostasis” via
1) Neural mechanism 2) Humoral (pituitary gland)
Where is the hypothalamus? What are the boundaries?
- Superior= hypothalamic sulcus i.e. the sulcus that separates the hypothalamus from the thalamus above
- Inferior= optic chiasma, tuber cinereum, & mamillary bodies
- Anterior= Lamina terminalis
- Posterior= midbrain/ interpeduncular fossa
**Note that the tuber cinereum is a hollow eminence of gray matter (part of the hypothalamus) situated between the mammillary bodies and the optic chiasm
What structure separates the hypothalamus into medial and lateral portions?
Fornix
What is the major blood supply to the hypothalamus?
Perforating branches from the Circle of Willis
What are the functions of the hypothalamus?
Homeostasis including:
- Sleep-wake cycle
- Integration of emotional responses & behavior
- ANS control center
- Temp. regulation
- Food intake
- Water balance/ thirst
- Endocrine system
What are the major inputs into the hypothalamus?
1) Limbic structures–emotions
2) Cerebral cortex–thoughts & decisions
3) Retina–light information
4) Brainstem & spinal cord–input from viscera
5) Intrinsic neurons i.e. osmoreceptors, chemoreceptors, & baroreceptors that monitor BP, osmolarity, glucose…etc.
How does the cerebral cortex effect they hypothalamus?
- You can’t “will” your heart rate to increase
- However, thinking about exciting things e.g. naked woman can increase HR
What are the major outputs of the hypothalamus?
1) Pituitary gland= hormones & hormone releasing factors
2) Brainstem & spinal cord= influences on the viscera
How are most of the nuclei of the hypothalamus named? What are the two exceptions to the general rule that the hypothalamic nuclei are named relative to their position?
Position in the hypothalamus
*****Note: arcuate & mammillary bodies are naked off of their shape, not position
What is the general function of the suprachiasmatic nucleus?
Circadian rhythm i.e. the suprachiasmatic nucleus is the “master clock” of the body
What is the general function of the mammillary bodies?
Processing emotional information
What is the general function of the anterior & posterior nuclei of the hypothalamus? What is the difference?
Regulation of body temperature
- Anterior= heat loss
- Posterior= heat conservation/ production
*****Remember, posterior= preservation
What are the general functions of the ventromedial & lateral nuclei of the hypothalamus? What is the difference between the two
Both the lateral & ventromedial nuclei control satiety and feeding
- Lateral= feeding or hunger center
- Ventromedial= satiety center
What is the general function of the supraoptic & paraventricular nuclei of the hypothalamus?
These two nuclei are associated with the posterior hypothesis/ “neurohypophysis”
- Synthesize & release hormones of the posterior pituitary
What is the general function of the preoptic, medial preoptic, arcuate, & paraventricular nuclei of the hypothalamus?
These four nuclei are associated with the anterior pituitary
- Produce & release factors that stimulate or inhibit the anterior pituitary
What does a lesion to the hypothalamus usually result in?
“Hypothalamic Syndrome”
- Manifestation damage to many hypothalamic nuclei
What tract sends light information to the suprachiasmatic nucleus?
Retinosuprachiasmatic tract i.e. from the retina
What type of receptors are in the suprachiasmatic nucleus?
Malatonin