Exam 3 Flashcards
Ribs 1-10 Articulate With
Sternum
Ribs 1-7 Articulate Via
Costal Cartilages
Ribes 8-10 Articulate Via
Cartilage from 7th Rib
Ribs 11-12
Floating Ribs/No Connection
Parts of Ribs
Head, Neck, Body, Tubercle
Head of Rib Articulates With
Bodies of Vertebrae and Intervertebral Disc; Costovertebral Joint
Tubercle of Rib Articulates With
Transverse Process of the Thoracic Vertebrae; Costotransverse Joint
Ribs that Articulate with only their own Vertebrae:
1st, 11th, 12th
Sternal End of Rib Articulates With
Costal Cartilage and the Sternum
First Rib
Scalene Tubercle on its Superior Surface, 2 grooves for Subclavian Artery, lower Brachial Plexus and Subclavian Vein, rarely fractured, would be dangerous for vessels
Cervical Rib
Remnant or development of a costal process on the C7 vertebra
Cervical Rib Problems
Thoracic Outlet Syndrome, compression of the subclavian artery and ischemic pain, lower brachial plexus compression and muscle weakness/pain, palpable mass in lower neck
Middle Rib Fractures
Most Common
Lower Rib Fractures
Damage the Pleura and Abdominal Viscera and even the kidney, liver, spleen
Flail Chest
Caused by multiple ribs fracture, thoracic wall moves freely (paradoxical), very painful with impaired ventilation
Parts of Sternum
Manubrium, Xiphoid Process, Body, Jugular Notch, Clavicular Notch, (8-9cm)
Sternal Angle
Angle of Louis, T4 vertebra level, manubiosternal joint
Sternal Puncture
Upper third of sternal body in the midline, bone marrow needle biopsy for bone marrow transfer or cytologic analysis
Median Sternotomy
Cut through the bone, procedure done to access the heart in coronary bypass or open heart surgery
Movements of Thorax
Widening for Inspiration and normal size for Expiration
How Thorax Moves:
Mobility in costovertebral joints, elevation of the sternum, mobility at manubrio-sternal joint, elasticity of costal cartilages, increased kyphosis of the thoracic column
Age Effect on Thorax Movement
Calcification of costal cartilage leads to loss of thoracic cage elasticity which restricts respiratory movements
Muscles that Elevate Thoracic Cage
Scalene Muscles, Sternocleidomastoid, Pectoralis Major/Minor
Scalene Muscles Function
Life upper ribs to move Thoracic Cage
Scalene Gap Contents
Subclavian Artery and Brachial Plexus
Intercostal Muscle Function
Elevate and Depress Ribs
Innervation: intercostal nerves
External Intercostal Muscle
Running obliquely, function during forced inspiration
Internal Intercostal Muscle
Running vertically, function both as expiratory and inspiratory muscles
Innermost Intercostal Muscles
May be missing, intercostal nerve, artery and vein are found between these muscles
Subcostalis Muscles
Fibers of the internal intercostal muscles that extend over several segments, function similarly to internal intercostals
Innervation: 4-11 intercostal nerves
Transversus Thoracis
Expiratory muscles from xiphoid process to the ribs on each side
Innervation: upper intercostal nerves
Muscles on Outside of Chest Wall
Pectorals Major/Minor, Serratus Anterior, REctus Abdominus, External/Internal Abdominal Obliques, Latissimus Dorsi, Trapezius
Internal Thoracic Artery
(IMA) Mammary Artery, origin is subclavian artery on each side, supplies thoracic wall, skin or region and back
Musculophrenic Artery
Starts in the sixth intercostal space, provides blood fro intercostal spaces 7, 8, 9
Superior Epigastric Artery
Originates from the Musculophrenic Artery, in the rectus sheath between the abdominal muscles
Inferior Epigastric Artery
Branch of the external iliac artery in the lower abdominal wall
Coarctation of the Aorta
Narrowing in the arch of the aorta compromising blood supply to thoracic, abdominal, and lower limb structures, arteries are dilated
Posterior Intercostal Arteries
Originate from thoracic artery, run in intercostal spaces
Thoracic Wall Veins
Posterior/Anterior Intercostal Viens drained by Azygos and Hemiazygous Viens drained into the Superior Vena Cava
Anterior and Posterior Intercostal Vessels
Internal thoracic Artery to Musculophrenic Artery,
Internal Thoracic Artery to Superior Epigastric Artery
Subcostal Nerve
Located in the intercostal space originates from T12, primary ventral rami of spinal nerves
Reasons to Enter Intercostal Spaces
Fractures of the ribs or Shingles
Procedure to Enter Intercostal Spaces
Intercostal nerve block, needle into lower border of rib, extreme care not to sever vessels and nerves
Tube Thoracotomy/Thoracocentesis
Draining pathologic air/gas from pleural cavity, entering needle close to upper border of rib, all layers pf pleura are punctured except for visceral pleura
Breast
Extends vertically from 2nd to 6th rib and transversely from sternum to the mid-axillary line, it extends into axilla where high percentage of tumors occur
Function: lactation
Tissue of Breast
Glandular tissue and Adipose tissue (contour and size)
Nipple Cell Type
Connective Tissue and Keratinizing Stratified Squamous Epithelium
Nipple at Puberty
Darkens due to melanin production and pigmentation
Internal Structure of Breast
Mammary Glands in adipose tide, ligaments of fibrous bands of tissue and superficial and deep fasciae for support
Suspensory Ligaments (of Cooper)
Extend from the skin to deep fascia and support the breast, tumor here may cause dimpling of skin.
Retromammary Space
Between breast and the deep fascia, tumor here may contract the pectoralis major and the breast may move superiorly
Mammary Glands
Exocrine and Apocrine glands, modified sweat glands, secreting part is the alveoli, each lobule is drained by a lactiferous duct which opens into the nipple
Alveoli
Lined with milk secreting cuboidal epithelium, controlled by hypothalamus
Innervation of Breast
Intercostal nerves, T4-T6
Dermatome of nipple is T4
Blood Supply of Breast
Internal thoracic, axillary and intercostal artery
Venous Drainage of Breast
End up with draining by axillary and azygous veins
Lymphatic Drainage of Breast
Axillary lymph nodes receive 75% of lymphatics, some in central group as well
Axillary Lymph Node Groups
Pectoral (medial), Lateral (humeral), Apical, Subscapular (posterior), Central
Left Side Lymphatics
Final drainage is Thoracic Duct
Right Side Lymphatics
Final drainage is larger veins at the venous angle
Progesterone
For the development of milk secreting lobules
Breast Cancer Sign
Dimpling (invagination) and thickening of skin especially if the lymphatic system is blocked, looks like an orange peel
Mastectomy
Removes breast completely, danger is in injury to long thoracic nerve
Lumpectomy
Surgery to remove cancer or other abnormal tissue from your breast
Gynecomastia
AKA Klinefelter’s Syndrome, men have one extra X chromosome, abnormally large breast in males, puberty and old age is when sign appear
Axillary Region Structures
Brachial Plexus, Axillary Artery, Vein, Lymph Nodes
Ultrasound Guided Infraclavicular Nerve Block
Anesthesia for surgery of the arm, forearm or hand, can be used for pain here as well (axillary region)
Mediastinum
The space between the right and left lungs: 1. Superior Mediastinum (supracardiac) 2. Inferior Mediastinum (anterior, middle and posterior)
Supracardiac Mediastinum
5 layers of structures.
- Thymus
- Great veins related to heart, the phrenic nerves, the thoracic duct and lymphatic trunks
- Arch of Aorta including its branches and the vagus nerves, sympathetic and parasympathetic nerves to the heart (cardiac plexus)
- Trachea and its bifurcation
- Esophagus, the recurrent laryngeal nerves
Pleura
Double layered membrane, serous membrane, produces serous fluid
Layers of Pleura
Visceral (inner) and Parietal (outer)
Other parts of Pleura
Costal, Cervical, Mediastinal, Diaphragmatic
Pleural Cavity
Serous fluid here serves as lubrication, no friction between lungs
Plural Cavity becomes wider near Diaphragm/Mediastinum
Costodiaphragmatic and Costomediastinal Recesses
Innervation of Pleura (Parietal Layer)
Somatic nerves, intercostal nerves, phrenic nerve
Innervation of Pleura (Visceral Layer)
Sensory autonomic nerves
Blood Supply of Parietal Layer
Intercostal and internal thoracic arteries, drained by same name veins
Lymphatics of Parietal Layer
Nodes of the internal aspect of the thoracic wall
Blood Supply of Visceral Layer
Lungs supply the blood here
Lymphatics of Visceral Layer
Follows the lungs, nodes in hilum of lungs
Significance of Intrapleural Pressure
Breathing Cycle = -3 cm H2O at rest, -6 cm H2O at inspiration, increase in both and elastic recoil strength of the lungs
Intrapleural Pressure is Disturbed
Interferes with respiration
Pneumothorax
Air is getting into the pleural cavity due to injury, pulmonary disease which leads to rupture of the visceral pleura, now positive pressure, which will collapse the lung and can be fatal
Puncturing the Intercostal Space Warnings
Always go superior to the inferior rib, not below the 9th intercostal space (danger to injure the liver on the right side)
Sucking Pneumothorax
Air enters and leaves the pleural cavity, mediastinal flutter which is the mediastinum shifted toward the normal side in inspiration and shifted to the injured side in expiration
Tension Pneumothorax
Air enters the pleural cavity and does not leave, increased intrathoracic pressures, patient now has dyspnea and/or cyanosis, seen by hyper-resonant percussion tone in radiolucent area in lung, in radiography.
Pneumothorax Surgical Procedure
Chest tube at -10cm H2O to reduce pneumothorax inserted anteriorly in 2nd intercostal space or if fluid is also present, in 5th-6th space (near posterior axillary line)
Inadvertent Damage to Pleura
Catheterization of the subclavian vein and brachial plexus block, injuries in the neck over the clavicle or during kidney surgery
Pleural Effusion
Excess fluid in the pleural cavity
Types of Pleural Effusion
Hydrothorax (eg: congestive heart failure)
Pyothorax (infection)
Chylothorax (injury to thoracic duct)
Hemothorax (blood in pleural cavity)
Pleuritis
Inflammation of the pleura, pain only if parietal pleura is involved, not the visceral layer
Respiratory System
Gaseous Exchange, blood pH, Blood Pressure, Protecting the Heart
Pharynx
Both respiratory and the digestive tract, merges into the esophagus at the level of the cricoid cartilage
3 Parts of Pharynx
Nasopharynx, Oropharynx and Hypopharynx (Laryngopharynx).
Lungs
Organs of respiration
Surfaces of Lung
Costal, Diaphragmatic, Mediastinal
Inferior Border of the Lungs
6th rib in midclavicular line, 8th rib in the midaxillary line, 10th rib in the scapular line
Children: one rib higher
Right Lung
3 lobes, larger and shorter
Left Lung
2 Lobes, upper lobe contains the cardiac notch and lingula is below the cardiac notch
Fissures of the Lungs
Oblique: T2 to 6th costochondral joint
Horizontal: from 4th costal cartilage level to the oblique fissure
Structures of the Hilum
Main bronchus, lobar bronchi, lower lobe brunches, pulmonary artery and veins, bronchial vessels, pulmonary plexus, lymph vessels, broncho pulmonary lymph node
Trachea
12 cm long and 2 cm wide, from C6 to T4, contains C-shaped cartilage rings, posteriorly has muscle layer covered by mucus membrane
Trachea Divides
Main Bronchi –> Lobar Bronchi –> Segmental Bronchi
Right Main Bronchus
Shorter (2.5 cm), wider and more vertical
Left Main Bronchus
Longer (5 cm), less steep
Bronchopulmonary Segments
10 in each lung, segments of bronchi branches
Bronchopulmonary Segments Contains
Segmental bronchus, branch of pulmonary artery and branch of bronchial artery run together
Right Lung Superior
Apical, Posterior, Anterior segments
Right Lung Middle
Lateral, Medial segments
Right Lung Inferior
Superior, Anterior Basal, Medial Basal, Lateral Basal, Posterior Basal segments
Left Lung Superior
Apical, Posterior, Anterior, Superior, Inferior segments
Left Lung Inferior
Superior, Anterior Basal, Medial Basal, Lateral Basal, Posterior Basal segments
Clinical Function of Bronchopulmonary Segments
Tributaries of the pulmonary vein, used as surgical markers
Blood Air Barrier
Thin membrane between capillaries and alveoli, gas exchange takes place here
Histology of Bronchioles
Simple ciliated columnar epithelium with goblet cells
Histology of Trachea
Pseudostratified ciliated columnar epithelium with goblet cells
Histology of Alveolar Ducts
Simple Squamous
Tidal Volume
.5 Liters
Inspiratory Reserve Volume
3 Liters
Expiratory Reserve Volume
1.2 Liters
Residual Volume
1.2 Liters
Vital Capacity or Forced Vital Capacity
4.7 Liters
Total Lung Capacity
5.9 Liters
FEV1 Equals about
80% of the Forced Vital Capacity
Lung Blood Supply
Pulmonary Arteries bring deoxygenated blood and Bronchial Arteries from intercostal arteries
Venous Drainage of Lung
Azygous System
Parasympathetic Nerve Supply To Lungs
Vagus Nerve (CN 10)
Sympathetic Nerve Supply To Lungs
T1-T5
Vague Efferent Nerve Supply To Lungs
Bronchoconstriction, Vasodilator, Secretomotor
Vagal Afferent Nerve Supply To Lungs
Sensory in respiratory epithelium(p)
Sympathetic Efferent Nerve Supply To Lungs
Bronchodilator, Vasoconstrictor, Inhibitory to glands in bronchial tree
Respiratory Structures in Respiratory Diseases
Involve airways, parenchyma of the lung, pulmonary vessels, pleura, nerves and muscles of respiration
Structural/Pathophysiological changes in COPD’s
Less air flows in and out of airways because the elastic quality of the airways is lost, narrowing go lumen
Asthma
Inflammation and edema of the bronchial wall, tightened bronchi an bronchioles and increased mucus production, constriction and narrowing of the lumen
Emphysema
Enlargement of distal air paces and damage to the lung and alveolar tissue, destruction of the alveolar walls, pink puffers, heave breathing and pink discoloration, difficult exhaling, barrel shaped chest
Chronic Bronchitis
Inflammation and swelling of the bronchial wall, mucous secretion, narrowing of small airways, blue bloaters, cigarette smoking or inhalation of chemicals as cause, often coughing, sputum production, chronic bacterial infection
Pulmonary Thromboembolis
Blood clots in the lung originating mainly from veins of the lower limb
Bronchiolar Carcinoma
(Lung Cancer) From epithelium of the bronchial tree
Pancoast’s Tumor
Apical lung tumor
Atelectasis
Collapse of alveoli due to infection or tumor or surfactant deficiency
Blood From the Heart Tissues Returns to
Coronary Sinus via Coronary Veins
Cardiac Output
Amount of blood pumped into the aorta and pulmonary trunk by the heart
Blood Pressures is Higher
Higher in Arteries than Veins
Serous Pericardium
Double layer thin sac of serous membrane
Parietal Pericardium
Outer membrane of the Serous Pericardium
Visceral Pericardium
Inner membrane of the Serous Pericardium (epicardium)
Pericardial Cavity
Space between the two layers of the serous membrane, contains pericardial fluid which serves as lubrication
Fibrous Pericardium
External cover of Serous Pericardium, dense connective tissue membrane, like a badd from the outside
Function of Pericardium
Keeps the heart inn the thoracic cavity, protects the heart against sudden overfilling when blood volume increases
Pericardial Sinuses
Seen when the fibrous and parietal serous pericardium are both opened, oblique and transverse pericardial sinuses
Transverse Sinus
Space posterior to ascending aorta and pulmonary trunk, anterior to superior vena cava, finger can pass through
Oblique Sinus
U shape blind recess posterior to heart., hand can pass through
Blood Supply of the Pericardium
Pericardiacophreic and Musculophrenic arteries
Venous Drainage of the Pericardium
Azygous Venous system and Pericardiacophrenic veins
Innervation of Pericardium
Sympathetic and Parasympathetic (vagus) nerves, phrenic nerve
Pericarditis
Inflammation of the serous pericardium, due to cardiac or systemic disabuses, increased amounts of pericardial fluid, compress and restrict hearts movements, friction rubbing, severe pain behind and above sternum
Pericardiocentesis
Removal of excess fluid from pericardial cavity, entering at 5th or 6th left intercostal space near sternum
Pericardial Effusion
Abnormal accumulation of fluid in the pericardial cavity, eads to an increased intrapericardial pressure which can negatively affect heart function
Cardiac Tamponade
Pressure on the heart that occurs when blood or fluid builds up in the space between the heart muscle (myocardium) and the outer covering sac of the heart (pericardium)
Heart Tissue Is
Myocardium
Myocardium is Covered By
Epicardium
Endocardium
Thin layer covering the inner surface of the heart
Ligamentum Arteriosum
Remnant of Ductus Arteriosus, goal was to stop blood from going to the pulmonaries
Right Superior Border of The Heart
Third Costal Cartilage
Left Superior Border of The Heart
Second Intercostal Space
Right Inferior Border of The Heart
Sixth Costal Cartilage
Left Inferior Border of The Heart
Fifth Intercostal Space
Heart Size
Child a relatively larger, lies higher, transversely located compared to the heart of adult
Atria Separated by
Atrial Septum
Ventricles Separated By
Interventricular Septum
Left Wall Ventricle
2-3 times thicker than the right ventricle
Blood Pressure Aorta
120/80 mmHg
Blood Pressure Pulmonary Artery
25/10 mmHg
Interventricular Septum
Thick as the wall of the left ventricle, consists of a lower muscular portion and upper membranous portion
Ventricular Septal Defect
Most common heart defects whose cause is unknown, genetic factors, excessive fatigue during exertion, pulmonary hypertension, thickening of these arteries and arterioles leads to increased pulmonary resistance in systemic circulation, Eisenmenger’s Syndrome
Mitral/Bicuspid/Left Atrioventricular Valve
Two leaflets, connected to papillary muscles by tendinous cords
Aortic Valve
Outflow of the left ventricle at the beginning of the aorta and consists of three semilunar cusps, Posterior, Left and Right
Aortic Sinus
Dilated portion of aorta that prevents the cusps from sticking to the wall during the closure of the valve
Right Atrium
Receives blood from the superior vena cava, inferior vena cava and coronary sinus
Atrial Septum
Double layered is membrane formed during gestation that divided the right and left atria from one another
Foramen Ovale
Turns into Fossa Ovais, fetal structure to stop blood from entering the lungs
Premature Closure of Foramen Ovali
Leads to right heart hypertrophy and left side under development
Atrial Septal Defect
Congenital malformation that presents as an opening between the atria, blood from left side goes to right side causing heart enlargement and a higher volume of blood to the lungs, larger detect could need cardiac catherization or open heart surgery
Septomarginal Trabeculae
Moderator Band, muscle bundle extending from the interventricle septum to anterior papillary muscle part of conductive system
Tricuspid Valve
Between right atrium and ventricle, anterior, posterior, and septal cusps
Pulmonary Valve
Anterior, Left and Right valves
Pathology of Valves
Inflammation or infections of cusps may lead to scar formation and narrowing of the valve orifice (stenosis)
Incompetency/Insufficiency of Valves
Occurs when valve is unable to close properly
Rheumatic Fever and Cardiac Function
Acute inflammation as a result of complication of chronic tonsillitis, pharyngitis (etc), by Streptococcus infection characterized by arthritis, chorea, skin involvement (erythema), subcutaneous nodules and carditis, nodules on the valve cause irregular blood flow, valvular incompetence (blood regurgitation) causing murmur, may cause stenosis
Skeleton of Heart
Fibrocartilaginous tissue the muscles and valves are built on this system
Conduction System of the Heart
Specialized muscle tissue (the impulse-conducting system), which spontaneously generates rhythmical impulses to stimulate the rest of the heart muscle to contract.
Sinus (Sinoatrial) Node
Keith Flack, pacemaker, 70 impulses per minute
Atrioventricular (Aschoff-Tamara) Node
Ventricular side of orifice of coronary sinus, 50-60 impulses per minute
Bundle of His (Atrioventricular Bundle)
Pierces the cardiac skeleton, left and right bundles, 45-25 impulses per minute
Right Bundle of His
Section passes through the mdoerator band
Left Bundle of His
Has 6 branches and stimulates inter ventricular septum, anterior and posture papillae muscles and left ventricle
Purkinje Fibers
Terminal ends of bundles, merge with cardiac muscles on the walls of ventricles
Innervation of Conduction System Sympathetic
5-6 upper thoracic segments, postsynaptic fibers end on SA and AV nodes, increases heart rate and contraction force
Innervation of Conduction System Parasympathetic
Vagus nerve terminates on many small ganglia on the heart, decreases heart rate and force
Electrocardiography
Test recording electrical activity of heart
P Wave
Represents atrial depolarization
QRS Complex
Represents depolarization of ventricles
T Wave
Represents ventricular repolarization
P-R Interval
Normally equal to less than 0.2 seconds
ST Segment
Isoelectric and indicated that ventricles are depolarized
Normal ECG
25 mm/s
Detect Abnormal Heart Rate/Rhythm
Look on ECG
Atrial Flutter
Supreventrivcular arrhythmias characterized by rapid atrial waves, AV node is unable to respond to all waves it is receiving, saw toothed baseline appearance, may lead to heart failure
Atrial Fibrillation
400-700 a minute, wavy baseline, absence of recognizable P wave, can develop congestive heart failure and syncope
Ventricular Tachycardia
Three or more ectopic beats of ventricular origin, greater than 100 beats per minute, life threatening, coronary artery disease
Ventricular Fibrillation
Most serious cardiac arrhythmias, potentially leading to cardiac rest, electrical activity is disordered, leading to rapid and unsynchronized contraction of ventricles, use of defibrillator
ECG Changes During Myocardial Ischemia
Critical during exercise or high metabolic energy demand reveals S-T segment depression
S-T Segment Elevated in Conditions:
Transmural Myocardial Infarction, Vasospastic Angina, Pericarditis
Auscultation
Listening to the sounds of the heart
First Heart Sound
QRS complex, closure of atrioventricular valves
Second Heart Sound
T wave, closure of semilunar valves
Third Heart Sound
In children due to rapid ventricular filing
Fourth Heart Sound
Due to atrial systole
Sites of Auscultation
Aortic Valve (right 2nd intercostal space), Pulmonary Valve (left 2nd intercostal space), Tricuspid Valve (left 5th rib, at sternal junction), Mitral Valve (left 5th intercostal space in midclavicular line)
Blood Supply of Heart
Right and Left coronary arteries, functional end arteries
Right Coronary Artery Branches
SA Nodal Artery, Right Marginal Artery, Posterior Interventricular Artery, AV Nodal Artery
Right Coronary Artery Supplies
Right Atrium, SA Node, AV node, posterior parts of inter ventricular septum
Left Coronary Artery Branches
Anterior Interventricular Artery, Circumflex Branch, Left Marginal Artery
Left Coronary Artery Supplies
Left Atrium, left ventricle, inter ventricular septum, AV bundles, SA Node
Blockage of Coronary Arteries Results
No alternative blood supply, myocardial infarction and death, heart attacks due to blockage of smaller arteries
Veins of Heart Drain To
Coronary Sinus to Right Atrium
Veins of the Heart
Great Cardiac, Middle Cardiac, Small Cardiac, Left Posterior Ventricular, Left Marginal, Oblique Vein of the Left atrium, Anterior Cardiac, Smallest Cardiac
Thesbian Valve
Valve on coronary sinus and right atrium
Atherosclerotic Plaque
Calcification or hemorrhage, blockage and narrowing of vessels, coronary angiography (contrast medium), femoral or brachial artery to heart, balloon at tip of needle to push fluid towards and widen the lumen and restore blood supply
Sympathetic Nerve
Increases heart rate, contraction force and impulse conduct of the heart
Sensory Information From Heart
Transmitted through sympathetic neves (T1-T5)
Parasympathetic Nerve
Decreases the heart rate and force, vasoconstrictor to the coronary arteries
Lymphatic Drainage of Heart
Drained by subperiardial plexus which eventually drained onto the left venous angle
Two Phases of Cardiac Cycle
Systole and Diastole
Systole Goal
Contraction, emptying of blood filled ventricles
Diastole Goal
Relaxation, ventricles filled with blood
Systole Stages
Isovolumetric Contraction and Ejection Period
Diastole Stages
Isovolumetric Relaxation and Filling Time
Structures of the Posterior Mediastinum
Esophagus, Esophageal plexus, thoracic aorta and branches, thoracic duct coming from the cisterns chill, azygos venous system, thoracic splanchnic nerves
Esophagus
Muscular Tube to Digestive tract
Blood Supply to Esophagus (Upper)
Inferior thyroid artery
Blood Supply to Esophagus (Middle)
4-5 esophageal arteries and bronchial arteries
Blood Supply to Esophagus (Lower)
Left gastric artery and inferior phrenic artery
Venous Drainage of Esophagus
By the inferior thyroid vein, azygous, hemiazygous, gastric veins
Innervation of Esophagus
Sympathetic and parasympathetic (vagus) nerves
Cardia
Where esophagus enters the stomach
3 Narrowings of the Esophagus
Upper Sphincter, Aortic, Diaphragmatic
Azygous Venous System Contains
Azygous, Hemiazygous, Ascending Lumbar, Accessory Hemiazygous
Sympathetic Chain
Visceral organs of the trunk are innervated by the autonomic nervous system
Route of Sympathetic Step 1
Myelinated preganglionic axons of the lateral horn neurons leave the spinal core through the ventral root
Route of Sympathetic Step 2
Passing through the white commenting rams to teach the sympathetic ganglion of the sympathetic chain
Route of Sympathetic Pathway 1
Axons synapse in the ganglion and leave to innervate
Route of Sympathetic Pathway 2
Other group of postganglionic fibers reach visceral organs in thorax
Route of Sympathetic Pathway 3
Another group of fibers reaching the ganglion don’t synapse and move on to synapse at other location
Route of Sympathetic Pathway 4
Another group of fibers leave the ganglia without surpassing and go pre vertebral ganglia
Lymphatic System
Lymphatic vessels collect lymph (excess tissue fluid and blood proteins from loose connective tissue) and carry this fluid (lymph) to the great veins in the neck, fluid flows only toward the heart
Thoracic Diaphragm
Dome shaped, musculotendinous structure separating the thoracic and abdominal cavities
Parts of Thoracic Diaphragm
Central tendon and muscular part (sternal, costal, lumbar)
Openings in Thoracic Diaphragm
Aortic hiatus (T12) , Esophageal hiatus (T10), Foramen for the inferior vena cava (T8)
Thoracic Diaphragm Function
Chief muscle of inspiration
Blood Supply of Thoracic Diaphragm
Inferior phrenic, superior phrenic, musculophrenic and pericardiophrenic arteries
Innervation of Thoracic Diaphragm
Phrenic nerve: C3, C4, C5 and L1-L2 nerves and intercostals (sensory)
Epithelial Tissue
Covers external and Internal surfaces and involved in protection absorption and secretion, can regernate
Junctions of Epithelial Tissue
tight, adhering, desmosomes, gap
Tight Junctions
Prevent molecules from passing between the cells, encircles the cell to secure it to neighboring cells
Adhering Junctions
All around the cell where microfilaments extend, supports the cell like a belt close to the neighboring cells
Desmosomes
Disc saved plaques connected across the intercellular space, contact with cytoskeleton to support the cell, only at points where cell has mechanical stress
Gap Junctions
Specialized channels called connecons, six subunits and allow ions to flow rapidly between cells
Classifications of Epithelial Cells
Squamous (flat), Cuboidal (cube), Columnar (tall and rod like) –> Simple (one layer), Stratified (multiple layers)
Simple Squamous Epithelium
Air Sacs of Lungs, Kidney Corpuscles
Simple Cuboidal Epithelium
Kidney Tubules, Thyroid Gland
Simple Columnar Epithelium
GI Tract, goblet cells
Ciliated Simple Columnar Epithelium
Uterine tube, cilia moves contents
Pseudo Cilitated Columnar Epithelium
Respiratory airways, goblet cells
Non Keratinized Stratified Squamous Epithelium
Esophagus, Vagina
Stratified Keratinizing Epithelium
Skin, five layers
Five Layers of Stratified Keratinizing Epithelium
Stratum basale, stratum spinosum, stratum granulosum, stratum lucid, stratum corneum
Dead Layer of Skin
Stratum corneum
Stratified Columnar Epithelium
Urethra and large ducts of glands
Stratified Cuboidal Epithelium
Ducts of salivary and mammary glands
Transitional Epithelium
Ureter, urinary blasser, urethra
Connective Tissue
Supports and connects the tissue
Loose Areolar Connective Tissue
Most widespread, cushion organs and under epithelial tissue
Adipose Connective Tissue
Matrix of fat cells, breast and kidneys
Reticular Connective Tissue
Reticular fibers and cells, spleen, bone marrow, lymph nodes
Dense Irregular Connective Tissue
Irregularly arranged fibers, fibrous joint capsule, dermis, submucosa
Dense Regular Connective Tissue
Parallel fibers, rows, ligaments and tendons
Cartilage
Firm, compressible, flexible structure, contains lots of water
Types of Cartilage
Hyaline, Elastic, Fibrocartilage
Hyaline Cartilage
Strong tissue, rich inc collagen fivers, row and column, surrounded by a capsule, joint surfaces, epiphyseal plates and embryonic skeleton
Elastic Cartilage
Matrix rich in elastic fibers, yellowish color, ear, epiglottis, larynx
Fibrocartilage
Matrix with collagen fibers, symphysis pubis and intervertebral discs
Scurvy
Vitamin C deficiency, due to inadequate college cross linking, leads to rupture of blood vessels and bleeding gums
Muscle Tissue
Responsible for movement of the body and contraction of the internal organs
Skeletal
Voluntarily controlled, 40% of body weight, long, multinuclear, striated cells
Cardiac
Branching, uninuclear, striated, walls of heart
Smooth
Spindle shaped, one nucleus, lack striation, propel content of organs
Nerve Tissue
Command center that controls the body function, contains excitable neurons
Glands
Specialized unicellular or multicellular structures that prices and secrete products via exocytosis
Types of Glands
Exocrine and Endocrine
Exocrine Secrete
Product through a duct
Endocrine Secrete
Product into circulation
Classification of Exocrine Glands
Apocrine, Holocrine, Merocrine
Apocrine Gland
Secretion, salivary, gastric, part of pancreas glands
Holocrine Gland
Pinched off portion of cell and secretion, mammary gland
Merocrine Gland
Disintegrating cell and secretion, sebaceous gland
Blood Tissue Types
Red Blood, Lymphocyte, Basophil, Monocyte, Eosinophil, Platelets, Neutrophil