Exam 3 Flashcards
Ectopic Rupture
Medical Emergency
Intense Pelvic and Lower Abd Pain
50% report shoulder pain
Leads to shock (Drop in BP, Spike in HR)
Ectopic Rupture
Dx Studies: Ectopic Pregnancy
Bimanual Exam
Serial B-hCG Levels (Slower rise than norm preg)
Transvaginal Ultrasound= Best Dx Tool
H&H
Culdocentesis
Laparoscopy (may also treat)
Most common site of Ectopic Pregnancy
Fallopian Tube
Implantation at any site other than endometrium
Ectopic Pregnancy
Risk Factors for Ectopic Pregnancy
Endometriosis PID (Pelvic Inflammatory Disease = key) Previous Ectopic (10% More likely) Increased Progesterone Assisted Reproduction Tube Abnormality (Sx, Birth, Sterilization)
Molar Pregnancy
46 Paternal Chromosomes
No Embryo
No Fetal Tissue
Complete Molar Pregnancy
2 Tx of Ectopic Pregnancy
Laparoscopy
Methrotrexate (Chemo–>destroys preg)
S/S Choriocarcinoma
Bloody, Brown Discharge
Elevated hCG
CA arose in placenta during pregnancy
Rare
Can Metastasize
Choriocarcinoma
Percentage of Females with molar pregnancy that develop Choriocarcinoma
20%
Important Teaching For Molar Pregnancy
STRESS: F/U hCG (Weekly then Monthly)
NO Pregnancy for at least 6 mo (Can Hide S/S)
Provide Support
Cure Rate for Choriocarcinoma
100% IF still in uterus w/ normal Subsequent Pregnancy
Termination of Pregnancy before viability
before 20 weeks
Abortion
Medical Termination of Pregnancy
Induced Abortion (Elective/ Therapeutic)
Miscarriage
Spontaneous Abortion
Roe v Wade 1973
Any woman may have an abortion within the first 12 wks of pregnancy
Abortion @>20 weeks of gestation
Illegal unless to save the life of mom
Abortion Method (12-20 weeks) 2nd Trimester
D&E (suction and evacuation)
Mifepristone w/ misopristol
80% of Spontaneous Abortions Occur w/in
The First Trimester
Before mom knows she is pregnancy–think heavy menses
Responsible for 50% of early spontaneous abortions
Fetal Chromosomal Abnormalities
Responsible for Late Spontaneous Abortion
weak cervix or maternal illness
Greatest Risk Factor for Spontaneous Abortion
AMA
> 35 years old
10% of birth defects are caused by
medications (OTC, Herbal, Street)
60% of woman use at least…
One Rx in pregnancy
FDA Maternal Medication Use
Category A
failed to show fetal risk - best choice
FDA Maternal Medication Use
Category B
animal studies failed to show fetal risk
FDA Maternal Medication Use
Category C
animal studies
show fetal risk
FDA Maternal Medication Use
Category D
evidence of human fetal risk
FDA Maternal Medication Use
Category X
studies have shown fetal abnormalities
DO NOT USE
Preferred Anticoagulant
Heparin
Leading cause of mental retardation
Alcohol During Pregnancy
Most Common teratogen
Alcohol During Pregnancy
Accutane
increase risk of spontaneous abortion & congenital deformity
Anticonvulsants-Valproic Acid, Carbamezapine
Increase risk of cognitive abnormality, neural tube defects, cleft pallet, and IUGR
Inhibits prostanglandin synthesis –> premature ductus arteriosis constriction
Salycilates (NSAIDS, ibuprofen, aspirin, motrin, advil)
List Salycilates
NSAIDS ibuprofen aspirin Motrin Advil
Salycilates Asc Pregnancy
Do NOT use in late pregnancy >20 wks
Increases Birth Defects
Prolonged/ Inhib Labor
Premature Ductus Arteriosis Constriction
Allows fetal circulation to bypass lungs
Tetracycline
–>yellow teeth & depresses skeleton growth
ACE Inhibitors
Risk birth defects
IUGR
Fetal Death
Warafin
Risk of spontaneous abortion
Fetal demise
Fetal & NB Hemorrhage
CNS defects