Exam 3 Flashcards
Ectopic Rupture
Medical Emergency
Intense Pelvic and Lower Abd Pain
50% report shoulder pain
Leads to shock (Drop in BP, Spike in HR)
Ectopic Rupture
Dx Studies: Ectopic Pregnancy
Bimanual Exam
Serial B-hCG Levels (Slower rise than norm preg)
Transvaginal Ultrasound= Best Dx Tool
H&H
Culdocentesis
Laparoscopy (may also treat)
Most common site of Ectopic Pregnancy
Fallopian Tube
Implantation at any site other than endometrium
Ectopic Pregnancy
Risk Factors for Ectopic Pregnancy
Endometriosis PID (Pelvic Inflammatory Disease = key) Previous Ectopic (10% More likely) Increased Progesterone Assisted Reproduction Tube Abnormality (Sx, Birth, Sterilization)
Molar Pregnancy
46 Paternal Chromosomes
No Embryo
No Fetal Tissue
Complete Molar Pregnancy
2 Tx of Ectopic Pregnancy
Laparoscopy
Methrotrexate (Chemo–>destroys preg)
S/S Choriocarcinoma
Bloody, Brown Discharge
Elevated hCG
CA arose in placenta during pregnancy
Rare
Can Metastasize
Choriocarcinoma
Percentage of Females with molar pregnancy that develop Choriocarcinoma
20%
Important Teaching For Molar Pregnancy
STRESS: F/U hCG (Weekly then Monthly)
NO Pregnancy for at least 6 mo (Can Hide S/S)
Provide Support
Cure Rate for Choriocarcinoma
100% IF still in uterus w/ normal Subsequent Pregnancy
Termination of Pregnancy before viability
before 20 weeks
Abortion
Medical Termination of Pregnancy
Induced Abortion (Elective/ Therapeutic)
Miscarriage
Spontaneous Abortion
Roe v Wade 1973
Any woman may have an abortion within the first 12 wks of pregnancy
Abortion @>20 weeks of gestation
Illegal unless to save the life of mom
Abortion Method (12-20 weeks) 2nd Trimester
D&E (suction and evacuation)
Mifepristone w/ misopristol
80% of Spontaneous Abortions Occur w/in
The First Trimester
Before mom knows she is pregnancy–think heavy menses
Responsible for 50% of early spontaneous abortions
Fetal Chromosomal Abnormalities
Responsible for Late Spontaneous Abortion
weak cervix or maternal illness
Greatest Risk Factor for Spontaneous Abortion
AMA
> 35 years old
10% of birth defects are caused by
medications (OTC, Herbal, Street)
60% of woman use at least…
One Rx in pregnancy
FDA Maternal Medication Use
Category A
failed to show fetal risk - best choice
FDA Maternal Medication Use
Category B
animal studies failed to show fetal risk
FDA Maternal Medication Use
Category C
animal studies
show fetal risk
FDA Maternal Medication Use
Category D
evidence of human fetal risk
FDA Maternal Medication Use
Category X
studies have shown fetal abnormalities
DO NOT USE
Preferred Anticoagulant
Heparin
Leading cause of mental retardation
Alcohol During Pregnancy
Most Common teratogen
Alcohol During Pregnancy
Accutane
increase risk of spontaneous abortion & congenital deformity
Anticonvulsants-Valproic Acid, Carbamezapine
Increase risk of cognitive abnormality, neural tube defects, cleft pallet, and IUGR
Inhibits prostanglandin synthesis –> premature ductus arteriosis constriction
Salycilates (NSAIDS, ibuprofen, aspirin, motrin, advil)
List Salycilates
NSAIDS ibuprofen aspirin Motrin Advil
Salycilates Asc Pregnancy
Do NOT use in late pregnancy >20 wks
Increases Birth Defects
Prolonged/ Inhib Labor
Premature Ductus Arteriosis Constriction
Allows fetal circulation to bypass lungs
Tetracycline
–>yellow teeth & depresses skeleton growth
ACE Inhibitors
Risk birth defects
IUGR
Fetal Death
Warafin
Risk of spontaneous abortion
Fetal demise
Fetal & NB Hemorrhage
CNS defects
Contraindicated Vaccines
Measles Mumps Rubella Varicella Activated (Nasal) Flu
Pregnant Nurses
Discuss w/ MD & inform work
Use universal precautions
Leave during X-rays
Pregnant Nurses use caution with patient assignments including:
Radioactive implants
Nuclear procedures
(Dx using radionucleides, antineoplastics, chemicals, anesthetic gases, sterilizing agents)
Caffeine
Increases risk of spontaneous abortion
Safe Amt of Caffeine
300mg daily
3 average sized cups of coffee
5A’s
Ask - About Advise- to quit smoking Assess- willingness to quit Assist- to quit Arrange- for follow up care * majority resume smoking w/in 1+ yo after birth
Smoking
significant modifiable cause of poor pregnant outcomes
d/t hypoxemia & chemicals
Nicotine–> decreased uterine blood flow
Smoking increases the risk of
Low-birth wt & IUGR Preterm delivery Fetal death SIDS Asthma Childhood CA Learning disabilities Infant ear & respiratory infections
Alcohol stopped mid pregnancy–>
inhibits protein synthesis
alters embryonic organization of cells - can not be fixed
Alcohol increases the risk of
miscarriage, stillbirth,and death
Congenital anomalies of eyes d/t alcohol
Palpebral fissures (sm eye opening) Strabismus (crosses) Ptosis (saggy) Myopia Widest
Congenital anomalies of nose d/t alcohol
Shortened, upturned, broad bridge
Congenital anomalies of mouth d/t alcohol
Mircognathia
Smooth philtrum
sm chin/ smooth upper lip
Midface of Fetal Alcohol Baby
Flattened
Cardiac defects (alcohol)
murmurs
atrial-septal defects
ventricular septal defects
FELOP
FSH Estrogen LH (Surge) Ovulation Progesterone *menstrual cycle order*
3 phases of Ovarian Cycle
Follicular Phase
Ovulatory Phase
Luteal Phase
Variable Phase of Ovarian Cycle
Follicular Phase
Days 1-14
Primary follicles=Immature, FSH –> growth into oocyte
Graafian follicle= small ovum, secrets EST
Follicular Phase of Ovarian Cycle
Days 15-28 of Ovarian Cycle
Fixed Time Frame
Luteal Phase
Upsurge of LH–>Ovulation
-Follicle ruptures, ovum free –>travels to Fallopian tube
Corpus luteum develops – remain follicle fills w/ fluid high in PRO
Luteal Phase
Fertilized Ovum –>
egg secrets HCG–> maintains Corpus Luteum (secretes PRO–>maintains pregnancy)
Ovum not fertilized–>
corpus luteum regresses–> Follicle atresia
Hormone that controls secondary female sex characteristics
Estrogen
Tattle tales w/ sense of justice
7 yo
Keep promises
7 yo
Will cheat to win
6 yo
Most important socializing agent is the peer group
6-12 yo
Marijuana –>
LBW
IUGR
Preterm Birth
Behavior Problems
Methamphetamine
SIDS
IUGR
Reduced brain growth
Development effects
Amniocentesis
14-16wk gestation High risk pregnancy US->local pocket of amniotic fluid 15-20 mL amniotic fluid aspirated, result in 2 wks <1% risk
Post Amniocentesis
Monitor FHR
RhoGam in Rh-
Minimal activity 24h –>decrease uterine irritability
Begins when estrogen levels peak & ends with the release of the oocyte
Ovulatory phase
3 phases of endometrial cycle
Proliferative
Secretory
Menstrual
Implantation
7-10d after fertilization
Depends on vascular changes of endometrium
genotype
persons genetic makeup
genome
organisms complete set of DNA
Key S/S of SBS (Shaken Baby Syndrome)
Subdural Hemorrhages (80%) Retinal Hemorrhage (50-100%)
Most likely perpetrator in SBS
Father (44%)
Mother’s BF (23%)
Least likely perpetrator in SBS
Mother is least likely
Highest form of Child Maltreatment
Neglect (63%) of Child Abuse Cases
Key in Child Maltreatment/ Abuse Cases
GOOD DOCUMENTATION
A report of child abuse is made…
q 10 secs
of children that die q day in the US from child abuse
5+
US= WORST industrialized nation
% of abused & neglected children that abuse their own children
30% of abused and neglected children later abuse their own children
Characteristics of Abusive Parents
Majority were abused Difficulty coping Younger Drug, Alcohol, and decreased support network Lack of education
Emotional/ Verbal Abuse Froms
belittling favoritism Corrupting Over-pressuring Isolation Ignoring
Deliberate attempt to destroy/ impair a child’s self-esteem or competence
Emotional/ verbal abuse
S/S of SBS (ICP)
Sleepy Irritable Vomiting = RED FLAG Respiratory Compromise Coma/ Death (Not Imminent)
Health Risk of Childhood Obesity
Cardiovascular Hyerinsulineamia Type II DM CA Sleep Apnea Orthopedic Problems Adult Obesity Social Discrimination
BMI
WT/HT
(LBS/IN)*703
Normal %tile range for wt
5-85
5-2-1-almost none
5 fruits/ veggies
2 hours screen time
1 hour of activity
Almost no soda etc
Tx Threatened Abortion
Limit Activity (1st 12-24h) No stress, sex, or fatigue Be honest (may/ may not loose baby)
S/S of Threatened Abortion
Cervix = Closed
Days of unexplained bleeding/ cramping
Risk of Expulsion
Complications of Elective Abortions
Hemorrhage Infection Uterine Perforation Cervical Laceration Retained products of conception
Immunological reactions against the sperm that causes a decreases in sperm motility
Sperm Antibodies
mainly w/ vasectomy reversal/ testicular trauma
Seaman Analysis
Abstains 2-3d before sample(s)
Ovarian Reserve Testing
day 3 of menses –>serum FSH and estradiol test
FSH>10 IU/l–>specialist
BBT
Basal Body Testing
+0.4* F x3days = ovulation
Detecting LH Surge
Surge in LH 36h before ovulation
Tested w/ Urine or Serum
-Ideal time for Sex if want Prego
Endometrial Biopsy
Outpatient
Assess Response of Uterus to hormonal signals
Performed at end of menses
Hysterosalpingogram
Radiological exam w/ dye
Info about endocervical canal, uterine cavity, and tubes
Myomectomy
Sx removal of uterine fibroids