Exam 2: Wk 2 CHF and Cardiac Muscle Dysfunction Flashcards
Define Heart Failure
inability of the heart to pump adequate amts of blood through the circulation
MAP - mean arterial pressure
BP over TIME
MAP= 1/3 x SBP + 2/3 x DBP
MAP = CO x TPR
Norm: 65-110mmHg
Total peripheral resistance
Amt of force exerted against the circulating blood by the vasculature of the body
What affects total peripheral resistance?
Blood volume and resistance to flow in blood vessels
Define pulse pressure and what is the formula q
How hard the heart is working - indicates efficiency
PP= SVP-DVP
After load - arterial pressure
Pressure or resistance the heart has to overcome to eject blood ; SQUEEZE
Amt of pressure that the heart needs to exert to eject the blood during ventricular contraction
Decreased TPR= _____ after load
Decreased
Increased after load = _____ contraction
Reduced/decreased
Preload - Venous Pressure
Stretch; the amt of volume being returned to the heart
Preload increases pumping force (contractility w stretch)
What system controls venous pressure
SNS
Each heart beat we get ___ in venous pressure and ____ in arterial pressure which causes blood to circulate.
Small decrease
Large increase
Stroke volume, cardiac output, ejection fraction
- SV = amt of blood ejected out of heart
- CO= HR x SV in one minute
- EF = (EDV-ESV)/EDV ; % of blood in ventricle ejected into arteries
CHF
Heart is failing to pump blood from veins to arteries
- venous pressure too high
- EF too low
- arterial pressure may not rise enough with each contraction
Which side of the heart has more work to do? Which side has more resistance?
L side of the heart has more work for L ventricle and higher overall resistance than pulmonary
Which side of heart is thicker? Does it have high or low pressure?
L Ventricle = high pressure
Therefore > O2 consumption than R
Which side of the heart usually fails first?
L side unless there’s an injury to the R
If L side fails, where does the pressure build up?
- How about R
L side Into the lungs so high pulmonary and low systemic pressure
What is it called when CO is balanced, regardless of demand on the heart?
COMPENSATED
What is it called when CO is NOT balanced, or cannot keep up with the demand on the heart?
DECOMPENSATED heart
What are the two most common causes of Cardiac muscle dysfunction
- HTN & CAD (MI)
Chronic hypertension
Increased arterial pressure whuch leads to L ventricular HYPERTROPHY
- leads to overstretched contractile fibers and less effective pump