Exam 2 Study Questions Flashcards
Exam 2
If you are missing a S, M, or L, opsin, what might be the symptoms?
Colorblindness
Steps of synaptic transmission (5)
- Action potential arrives at terminal
- VGCa2+ channels open and Ca2+ rushes into cell
- Ca2+ warps the synaptic vesicles, releasing NTs
- NTs diffuse across the synapse
- NT binds to receptor of pstn
Light transduction in light (6-7)
- Light hits opsin
- Opsin activates it’s G-protein, which diffuses across the cell
- The G-protein activates the PDE
- PDE catalyzes cGMP and turns it into GMP
- Lack of cGMP CLOSES the ion channel
- Membrane becomes more negative
- NT Glu is not released
Do photoreceptors release NT Glu in the dark or in the light?
Dark
Is Glutamate excitatory or inhibitory in ON BPC
Inhibited
Off in dark
- Glu is released
- Excitatory Glu excites the cell
- Releases NT to P or M ganglion
- Ganglion sends AP
On in light
- No inhibitory glu is released
- Cell is depolarized
- Releases NT to P or M ganglion
- Ganglion sends AP
Rods have high/low spatial resolution, high/low sensitivity to light, and are responsible for _________ Vision
Low; High; Black and white
Cutting the optic chiasm will affect the
Left nasal and right nasal; Outer portions of L and R visual field
What does the basilar membrane do?
Moves up the Organ of Corti, which bends the hair cells.
Where is the endolymph? High/Low K+ ECF conc?
Top around the stereocilia; High (K+ flows in)
Where is the perilymph? High/Low K+ ECF conc.
Below around the Cell body; Low (K+ flows out)
What do hair cells release onto the spiral ganglion cell?
Glutamate
Steps of audition in the hair cell
- Basilar membrane moves up
- K+ and Ca2+ flows into the hair cells
- Cell is depolarized
- The VGCa2+ open allowing for Ca2+ to flow inside
- The cell body releases glutamate to post spiral ganglion
- Ganglion sends AP
How do we code for frequency of sound?
Tonotopy (Location based excitation)