Exam 2 - Pyoderma Flashcards
what is the most common agent involved in pyoderma?
staphylococcus pseudintermedius
what is pyoderma? why is it important?
pyogenic (pus-producing) bacterial infection of the skin
common cause of skin disease in companion animals - especially dogs
T/F: pyoderma is almost always occurring secondarily to an underlying cause
true
why does depth of infection matter?
dictates the appropriate duration of antibiotic therapy & helps guide treatment
how do we determine depth on skin infections?
diagnostic work up - look at lesion types, clinical signs, cytology/skin scrape, & biopsies
what is another name for pyotraumatic dermatitis?
hotspot
what is this lesion?
hot spot - pyotraumatic dermatitis
do you need systemic antibiotic therapy for superficial bacterial skin infections?
lecture she gave said no, but the notes state otherwise???
yes - required for most cases along side topical therapies
can you tell by looks alone that a patient has a methicillin-resistant staph infection?
nope
what is the difference between resident bacteria & transient bacteria in regards to the normal commensal organisms of the skin?
resident - capable of living & multiplying on normal skin
transient - not capable of multiplying on normal skin
commensal bacteria will not normally evoke an immune response from the host unless what?
conditions favoring overgrowth are occurring
______ bacterial skin conditions are uncommon while _______ bacterial skin conditions are common because of opportunistic pathogens
primary - uncommon
secondary - common
T/F: staphylococcus pseudintermedius is RARELY isolated from normal and diseased human skin/mucosa
true
what is the most common bacterial agent involved in human skin disease?
staph aureus
what is the pathophysiology of pyoderma?
bacterial adherence leads to colonization & penetration of abnormal skin which may produce/release enzymes & toxins which act as super antigens
what are some examples of alteration & function in the skin that lead to conditions allowing pyoderma to occur?
- faulty epidermal barrier function
- abnormal cutaneous microclimate
- aberrant immune response - either allergic response or immunosuppression
if you see cocci on skin cytology, what are you thinking?
staphylococcal bacteria until proven otherwise!!!!
T/F: often times, treating the staphylococcal component of a mixed infection with rod-shaped bacteria will result in clinical resolution of the pyoderma
true
what are the most common pathogens isolated from pyoderma in cats?
s. pseudintermedius & s. aureus
what are the agents involved in cat-bite abscesses?
pasteurella multocida (normal inhabitant of the mouth), strep spp., & anaerobic pathogens
how is canine pyoderma classified?
based off of the cutaneous depth of infection & appropriate duration of therapy
T/F: pyoderma is assumed to be related to staph spp unless there is a qualifier to denote otherwise
true
why are b-lactam antibiotics empirically prescribed for animals with superficial pyoderma/folliculitis? what are examples of drugs used?
most commonly associated with staph organisms & they have a wide spectrum of activity against staph spp - all used for at least 3-4 weeks, 1 week past clinical resolution
cephalexin 22-30mg/kg twice daily
cefpodoxime 10mg/kg once daily
clavamox 20mg/kg 3x a day
cefovecin 8mg/kg q 14 days
other than abscesses & cellulitis, other forms of what disease are not as common in cats when compared to dogs?
other forms of pyoderma