Exam 2 part 5 Flashcards
Chromosome mutations
change from normal chromosome structure and/or number
change in gene expression pattern, if organism is viable
detectable through karyotyping
occurs commonly
Euploid
number of chromosomes in individual’s cells is a multiple of normal haploid set
aneuploid
not a multiple of normal haploid set; one or more extra/missing chromosomes
Nondisjunction
homologous chromosomes during anaphase I or sister chromatids during anaphase II do no segregate properly
Nullisomy
both homologous chromosomes are absent
embyronic lethal
Monosomy
one chromosome missing 2n-1
trisomy
one extra chromosome
2n+1
tetrasomy
2 extra chromosomes
2n+2
Trisomy 21 and advanced maternal age
oocytes are arrested in prophase I each moth after puberty, meiosis continues in 1 egg
Monoploidy
one set
Diploidy
2 sets
Polyploidy
at least 2 sets
Ploidy levels
monoploidy
diploidy
polyploidy
Monoploidy vs Haploidy
Monoploidy results from mitosis
Haploidly results from meiosis
autopolyploidy
extra set of chromosomes is identical to noromal haploid set