Exam 2: Ion Effects Flashcards
Does chloride want to come into or out of the cell?
Inside the cell
What does chloride do to the Vrm of the inside of the cell? Does this make the cell more depolarized, repolarized, or hyperpolarized?
Chloride will make the Vrm of the inside of the cell more negative, meaning that the cell will become hyperpolarized. Cells will become more difficult to excite when chloride comes in
What happens when we take chloride away?
We have seizures because chloride helps keep the activity level controlled in the body
When Ca comes into the cell what does it do to the Vrm? Does this make the cell more depolarized, repolarized, or hyperpolarized?
When calcium comes into the cell it wants to flood in and make the inside of the cell more positive. This causes the cell to have a massive depolarization
Where does calcium tend to “sit”?
At the cell wall
What is the closest entry for calcium channels?
Leaky sodium channels
What happens if calcium blocks sodium channels?
This would cause an inhibition of electrical activity in the cell because sodium would be blocked from flooding into the cell for action potentials
What happens when the potassium in the ECF increases?
This would make potassium not want to leave the cell as easily, meaning more potassium would remain in the cell, making the cell more positive
What can you give to patients to help block sodium permeability?
Calcium
Does calcium block potassium channels?
Yes, but the potassium is wanting to leave the cell so it will push calcium out of the way
What happens when we have a lack of calcium?
There is overactivity of motor neurons because sodium is constantly flooding into the cells and causing action potentials
T/F Magnesium functions completely opposite of calcium
False; it acts similarly to calcium
What type of patients is magnesium useful with?
People with heart problems
