Exam 2 extra stuff Flashcards

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1
Q

Cells use membranes to help maintain set ranges of ion concentrations inside and outside the cell. Which of the following ions is the most abundant inside a typical mammalian cell?

A

K+

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2
Q

Several different classes of enzymes are needed for the catabolism of carbohydrates. Which of the following descriptions best matches the function of a KINASE?

  • An enzyme that catalyzes the rearrangement of bonds within a single molecule
  • An enzyme that catalyzes a change in the position of a specific chemical group within a single molecule
  • An enzyme that catalyzes the oxidation of a molecule by removing a hydroide ion
  • An enzyme that catalyzes the addition of phosphate groups to other molecules
A

An enzyme that catalyzes the addition of a phosphate groups to other molecules

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3
Q

In living cells, the gradual oxidation of glucose during cellular respiration is favored over combustion to CO2 and H2O in a single step because ______.

A

Energy is released stepwise, in small amounts.

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4
Q

The reaction cycle that uses acetyl CoA to generate electron carrier molecules needed in the electron-transport chain is important for powering the cell. Which of the names below is not one commonly used to describe this reaction?

  • tricarboxylic acid cycle
  • krebs cycle
  • electron transport chain
  • citric acid cycle
A

electron transport cycle

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5
Q

Which of the following cells rely exclusively on glycolysis to supply them with ATP?

  • anaerobically growing yeast
  • aerobic bacteria
  • skeletal muscle cells
  • plant cells
A

anaerobically growing yeast

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6
Q

In oxidative phosphorylation, ATP production is coupled to the ecents in the electron-transport chain. What is accomplished in the final electron-transfer event in the electron-transport chain?

  • OH- is oxidized to O2
  • pyruvate is oxidized to CO2
  • O2 is reduced to H2O
  • NAD+ is reduced to NADH
A

O2 is reduced to H2O

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7
Q

The final metabolite produced by glycolysis is _____.

  • Acetyl CoA
  • Pyruvate
  • 3-phosphoglycerate
  • glyceraldehyde 3-phosphate
A

pyruvate

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8
Q

K+ leak channels are found in the plasma membrane. These channels open and close in an unregulated, random fashion. What do they accomplish in a resting cell?

  • they set the K+ concentration gradient to zero
  • They set the membrane potential to zero
  • They disrupt the resting membrane potential
  • They establish equilibrium where net movement of K+ is zero
A

They establish equilibrium where net movement of K+ is zero

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9
Q

Steps 7-10 of glycolysis result in substrate-level phosphorylation. Which of the following best describes this process?

  • ATP is being hydrolyzed to phosphorylate the substrate
  • The energy derived from substrate oxidation is coupled to the conversion of ADP to ATP
A

the energy derived from substrate oxidation is coupled to the conversation of ADP to ATP.

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10
Q

If Na+ channels are opened in a cell that was previously at rest, how will the resting membrane potential be affected?

  • the potential is not affected by NA+
  • It becomes more negative
  • It becomes more positive
  • It is permanently reset
A

It becomes more positive

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11
Q

The concentration of H+ ions inside the mitochondrial matrix is lower than it is in the cytosol or the mitochondrial inter-membrane space. What would be the immediate effect of a membrane-permeable compound that carries are releases protons into the mitochondrial matrix?

A

inhibition of ATP synthesis

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12
Q

_____ produced in the citric acid cycle and glycolysis donates electrons to the electron-transport chain.

A

NADH

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13
Q

_____ acts as the final electron acceptor in the electron-transport chain

A

oxygen

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14
Q

The synthesis of ATP in mitochondria is also known as ______

A

oxidative phosphorylation

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15
Q

T/F: Activated carrier molecules FADH2 and NADH store heat energy for the cell to use later.

A

FALSE. They donate e- to the electron transport chain

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16
Q

T/F: Catabolism is a general term that refers to the process by which large molecules are synthesized from smaller molecules.

A

FALSE. Anabolism

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17
Q

T/F: Fuel sources, including amino acids, fats, and carbohydrates, must be converted to acetyl CoA before they can be oxidized by the citric acid cycle.

A

True

18
Q

T/F: all electron carriers of the electron transport chain are large protein complexes that are in a fixed position within the inner mitochondrial membrane.

A

False – some e- carriers are mobile

19
Q

Where does glycolysis take place?

A

cytosol

20
Q

Where does the citric acid cycle take place?

A

mitochondrial matrix

21
Q

Where does the conversion of pyruvate to activated acetyl groups take place?

A

In mitochondrial matrix

22
Q

Where does the oxidation of fatty acids to acetyl CoA take place?

A

Mitochondrial matrix

23
Q

Where does the oxidative phosphorylation take place?

A

Inner membrane of the mitochondria

24
Q

T/F: Dehydrogenase enzymes catalyze the oxidation of a molecule by removing a hydride ion.

A

True

25
Q

During glycolysis, glucose molecules are broken down to yield _____.

A

Pyruvate + ATP + NADH

26
Q

An energy-liberating pathway is also known as ____.

A

catabolic

27
Q

What is true of NAD+

A

it is a coenzyme

28
Q

The nuclear membrane functions as a ____.

A
  • means of separating nuclear and cytoplasmic constituents
  • means of localization of the chromosomes within the cell
  • selective barrier, allowing certain substances in or out
  • means of sequestering many of the mRNA processing activities from the cytosol
    (ALL THE ABOVE)
29
Q

Which of the following is NOT a function associated with the cytoskeleton?

  • scaffold for support and maintenance of cell shape
  • anchoring site for mRNA during transcription
  • cell division
  • organizes the organelles within the cytoplasm
  • signal transducer
A

anchoring site for mRNA during transcription

30
Q

What characteristics best describes collagen?

A
  • triple helix
  • part of the extracellular matrix (ECM)
  • most abundant protein in the ECM
31
Q

In biological systems, oxidation is often described in terms of ____.

A

dehydrogenation

32
Q

Which of the following cell junctions are essential for the proper function of intestinal epithelial cells?

A
  • gap junctions
  • adhesive junctions
  • tight junctions
  • desmosomes
    ALL THE ABOVE
33
Q

What is the best statement that best describes the role of NAD+/NADH in glycolysis?

A

NAD+ is used to carry electrons

34
Q

Which of the following substances is required in the citric acid cycle reactions as an electron acceptor?

A

NAD+

35
Q

Electrons are passed to the electron transport system from

A

NADH and FADH2

36
Q

The major structural elements of the cytoskeleton are

A

microtubules, microfilaments, and intermediate filaments

37
Q

Where does the breakdown of pyruvate occur?

A

mitochondrial matrix

38
Q

Where does the citric acid cycle occur?

A

mitochondrial matrix

39
Q

Where does the electron transport chain occur?

A

inner mitochondrial membrane

40
Q

How is the H+ gradient created and how is such a gradient used to generate ATP?

A

The H+ electrochemical gradient is created by H+ donors such as NADH and FADH2 losing their e-, and generating a gradient.

This gradient then triggers and runs the rotary machine responsible for synthesizing ATP from ADP.