Exam 1 Material Only Week 2

Question 1

Bacteriostatic Abx

Answer 1

Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tretracyclines
Chloramphenicol

We’re ECSTaTiC about Bacteriostatics

Question 2

Bacteriocidal Abx

Answer 2

Vancomycin
Flouroquinolones
Penicillin
Aminoglycosides
Cephalosporin
Metrodanizole

Very Finely Proficient At Cell Murder

Question 3

Time-Dependant Abx

Answer 3

Beta-Lactams
Cephalosporins
Glycopeptides

Question 4

Beta-Lactam Abx are

Answer 4

Penicillins
Cephalosporins
Carbapenems
Monobactams

Question 5

Cell-Wall inhibitors

Answer 5

Beta-Lactam
Glycopeptides
Fosfomycin

Question 6

Beta-Lactam Abx differentiate based on

Answer 6

Functional group attached

Question 7

Bacteria attack Beta-Lactam with

Answer 7

Beta-Lactamases

Question 8

Beta Lactams MOA

Answer 8

Inhibit cell wall synthesis by inhibiting Transpeptidase (Penicillin Binding Protein PBP)
Causes cell lysis

Question 9

Bacteriostatic or Cidal?

Beta-Lactams

Answer 9

Bactericidal

Question 10

Mechanism of Resistance to Beta Lactam

Answer 10

Increase # of PBO enzymes
Change binding characteristic

Question 11

Penicillin Coverage

Answer 11

Gram + (Strep Pyogenes, Viridans Strep, susceptible S Peneumoniae)
Gram - (N Meningitis, Pastueuella Mul)
Anaerobes (Clostridium)
Syphilis (Particularly neurosyphilis)

Not S Aureus due to penicillinase production

Question 12

Penicillin Indication

Answer 12

Bacterial Pharyngitis (GAS, S Pyogenes; Prevent Rheumatic heart disease)
Syphilis

Question 13

Forms of Penicillin

Answer 13

Natural
Aminopenicillin
Antistaphylococcal
Antipseudomonal

Question 14

Penicillin S/E

Answer 14

Anaphylaxis
Rash
Nausea
Seizure
Hyperkalemia

Question 15

Antistaphylococcal Coverage

Answer 15

S Aureus
Staph Epidermidis

Narrower Spectrum; No Gram -, MRSA/ORSA, Enterococcus