Exam 1 - Chapter 5

Question 1

_____oma

Answer 1

Benign tumor

Question 2

Carcinoma

Answer 2

Malignant tumor arising from surface, glandular, or parenchymal epithelium

Question 3

Sarcoma

Answer 3

Malignant tumor arising from everywhere else carcinoma doesn’t arise from

Question 4

Leukemia

Answer 4

Neoplasm of blood cells

Question 5

Lipoma

Answer 5

Soft tissue lumps under the skin made of fat

Question 6

Blastoma

Answer 6

Tumors composed of embryonic cells originating from embryonic primordia

Question 7

Metastasis Steps

Answer 7

1. Primary tumor
2. Metastatic clone evolves
3. Clone replicates and inserts into the bloodstream
4. Transport by circulation
5. Embolization
6. Invasion of new tissue
7. New tumor formation

Question 8

Chemical Carcinogens

Answer 8

Polycyclic aromatic hydrocarbons, Aromatic amines, Nitrosamines & heavy metals

Question 9

Carcinogenesis Steps

Answer 9

1. Initiation
2. Promotion
3. Conversion
4. Progression
5. Clonal Expansion

Question 10

DNA Viruses That Can Cause Cancer

Answer 10

– Human papilloma virus (HPV)
– Epstein-Barr virus (EBV)
– Hepatitis B virus (HBV)

Question 11

RNA Viruses That Can Cause Cancer

Answer 11

Human T-cell leukemia/lymphoma virus

HTLV-1

Question 12

Phosphoprotein

Answer 12

Proteins that get a phosphate group added through the process of phosphorylation

Question 13

p53

Answer 13

Tumor suppressor gene that turns off replication of damaged DNA so it can be repaired. If it can’t be repaired, it makes the cell undergo apoptosis. When mutated, p53 can be a cause of cancer

Question 14

Cachexia

Answer 14

Found in some terminal final stages of cancer. It’s basically nothing but skin and bones left. The cancer cells steal all the body’s nutrients leaving the normal cells with nothing