Exam 1 - Chapter 2 Flashcards
Transudate
Edema with a low potein content (specific gravity
Exudate
Edema with a high protein content (specific gravity >1.0) and contains inflammatory agents. Three types:
Serous
Fibrinous
Purulent
Serous Exudate
Yellow color but contains no signs of a cell inflammatory response
Fibrinous Exudate
Contains a lot of fibrin because it was caused by a coagulative response
Purulent Exudate
Contains cell components, usually caused by infection
Bradykinin
Similar to histamine but causes pain
Arachidonic Acid
Derived from phospholipids from phospholipidases. Has two pathways which both create unpleasant molecules:
Lipoxygenase
Cyclooxygenase
Lipoxygenase Pathway
Leads to lipoxins. Asthma inhibitors block this pathway
Cyclooxygenase Pathway
Leads to prostaglandins. Aspirin and Celebrex blocks this pathway. There’s COX-1 and COX-2 (more common and easier to inhibit because of its larger binding site). The drugs either inhibit thromboxin or prostacyclin
Serous Inflammation
Early stage and leads to serous exudate
Fibrinous Inflammation
Leads to fibrinous exudate
Purulent Inflammation
Acute inflammation. Leads to purulent exudate. White blood cells’ enzymes cause liquefaction of the tissue it’s trying to save. The liquefaction leads to pus formation
Ulcerative Inflammation
Necrosis near the surface leads to ulcers
Pseudomembranous Inflammation
Acute inflammation. In response to a bacteria’s toxin. The bacteria is able to make false membranes on our own cells, so the body attacks these membranes
Granulomatous Inflammation
Chronic inflammation characterized by granulomas and giant cells