Exam 1: Biochemical, Physical, and Functional Assessment Flashcards

1
Q

What is the importance of biochemical and laboratory data in performing a nutritional assessment

A
  • objective data
  • used to diagnose nutrient deficiencies and toxicities
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2
Q

What is the importance of physical attributes in performing a nutritional assessment?

A
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3
Q

What is the importance of functional status in performing a nutritional assessment?

A
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4
Q

Identify types of laboratory specimens

A
  • Whole blood (glucose, hemoglobin…)
  • Serum (no clotting factors)
  • Plasma (yes clotting factors)
  • Blood cells
    ⚬ Erythrocytes
    ⚬ Leukocytes
  • Blood spots (babies- genetic metabolic disorders)
  • Other tissues
  • Urine
  • Feces
  • Breath tests (SIBO small intestinal bacteria overgrowth, or intolerances)
  • Hair/nails (micronutrients)
  • Saliva
  • Sweat (cystic fibrosis)
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5
Q

Identify types of Chemistry panels (laboratory tests)

A
  • Basic metabolic panel (BMP)
  • Comprehensive Metabolic Panel (CMP)
  • Complete Blood Count (CBC)
  • Stool testing
  • Urinalysis
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6
Q

Whats included in BMP?

A
  • BUN
  • Calcium
  • Chloride
  • CO2
  • Creatinine
  • Glucose
  • Potassium
  • Sodium
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7
Q

Whats included in CMP?

A

BMP plus
* Albumin
* ALP- Alkaline Phosphatase
* ALT- Alanine Tranaminase
* AST- Aspartate Aminotransferase
* Bilirubin
* Total protein

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8
Q

Whats included in CBC?

A

RBCs
⚬ Hg Hemogloblin
⚬ Hct Hematcrit- % of packed red blood cell in blood
⚬ MCV mean corpuscular value (mean avg cell size)
⚬ MCH mean corpuscular hemoglobin
⚬ MCHC mean corpuscular hemoglobin concentration
⚬ WBCs white blood cells

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9
Q

Whats included in stool testing?

A
  • Blood
    ⚬ Pathogens
    ⚬ Gut flora
    ⚬ Fat
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10
Q

Whats included in Urinalysis?

A

pH
⚬ Protein
⚬ Glucose
⚬ Ketones

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11
Q

What is hydration status

A

water regulation is vital for electrolyte balance
assess for dehydration and edema

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12
Q

Dehydration is

A

excessive loss of water and electrolytes from

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13
Q

What are the causes dehydration

A

vomiting; diarrhea; excessive laxative abuse; diuretics; fistulas; GI suction; polyuria; fever; excessive sweating; or decreased intake caused by anorexia, nausea, depression, or limited access to fluids.

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14
Q

What are the symptoms of dehydration?

A

rapid weight loss, decreased skin turgor, dry mucous membranes, dry and furrowed tongue, postural hypotension, a weak and rapid pulse, slow capillary refill, a decrease in body temperature

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15
Q

What is edema

A

an increase in the extracellular fluid volume
- inc albumin level

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16
Q

What are the causes edema

A

an increase in capillary hydrostatic pressure or capillary permeability or a decrease in colloid osmotic pressure. It often is associated with renal failure, chronic heart failure, cirrhosis of the liver, Cushing’s syndrome, excess use of sodium-con- taining intravenous fluids, and excessive intake of sodium-containing food or medications

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17
Q

What are the symptoms of edema

A

rapid weight gain, periph- eral edema, distended neck veins, slow emptying of peripheral veins, a bounding and full pulse, rales in the lungs, polyuria, ascites, and pleu- ral effusion

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18
Q

Hydration status tests

A

Serum sodium
Blood urea nitrogen
Serum osmolality

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19
Q

What is inflammation

A

a protective response by the immune system to infection, acute illness, trauma, toxins, many chronic diseases, and physical stress.

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20
Q

describe the inflammatory process

A
  • Release of pro-inflammatory cytokines and eicosanoids
    ⚬ ↓ hepatic protein synthesis, ↑ muscle protein breakdown
    ⚬ Redistribution of albumin
    ⚬ Iron stores shift from hemoglobin to ferritin
21
Q

What are the triggers of inflammation

A

⚬ Infection
⚬ Illness

⚬ Chronic disease
⚬ Physical stress

⚬ Trauma
⚬ Toxins

22
Q

What are acute reactatns

A

indicators for inflammation

23
Q

What are the positive acute phase reactants with inflammation

A

positives increase in response to inflammation
- C reactive protein
- ferritin

24
Q
  • C reactive protein
A

sensitive measure of chronic inflammation seen in patients with atherosclerosis and other chronic diseases (Wang et al, 2017). Although the exact function of CRP is unclear, it increases in the initial stages of acute stress—usually within 4 to 6hours of sur- gery or other trauma. Furthermore, its level can increase as much as

25
Q
A

synthesis of ferritin increases in the presence of inflammation. Ferritin is not a reliable indicator of iron stores in patients with acute inflammation, uremia, metastatic cancer, or alcoholic-related liver diseases. Cytokines and other inflammatory mediators can increase ferritin synthesis, fer- ritin leakage from cells, or both. Elevations in ferritin occur 1 to 2 days after the onset of the acute illness and peak at 3 to 5 days.

26
Q

What are the negative acute phase reactants with inflammation

A

Decreasing values when there’s inflammation in the body
-Albumin: half-life 18-21 days, affected by hydration
-prealbumin (PAB): half-life 2 days, affected by zinc status

27
Q

What do you look for in anthropometric measurements

A

Height/length
* Weight
* Body composition
* Girth measurements
⚬ Head
⚬ Midarm
⚬ Waist
■ Risk factor:
⚬ Waist-to-hip ratio
⚬ Waist-to-height ratio

28
Q

body composition methods

A

skin fold test
DXA (gold standard)
Bod Pod
Hydrostatic weighing

29
Q

Wasit risk factors for men and woman

A

men >40
woman > 35 in

30
Q

Significant weight loss by month

A

5% month 1
7.5% month 3
10% month 6

31
Q

NFPE techniques

A

Inspection
⚬ Palpation
⚬ Percussion
⚬ Auscultation

32
Q

NFPE examination areas

A
  • subcutaneous fat loss
  • muscle loss
  • presence of edema
33
Q

areas - subcutaneous fat loss

A

eyes
triceps
ribs

34
Q

areas of muscle loss

A

temples
jaws
clavicles
scapulae
interosseous

35
Q

edema areas

A

ankles and hands

36
Q

clinical characteristics of adult malnutrition

A

A minimum of two of the six characteristics below is recommended for diagnosis of malnutrition

37
Q

if calcium levels are low, what lab do you check for?

A

Albumin level in CMP and do a corrected calcium level

38
Q

serum Sodium level is indicator for

A

hydration status

39
Q

Serum potassium status is assess for patient with

A

renal disease or heart failure

40
Q

CO2 level is assess for patient with

A

respiratory problems

41
Q

BUN and creatine level are indicators for

A

kidney function

42
Q

Albumin and total protein levels are indicators for

A

protein status

43
Q

ALP, ALT, ASP, Bilirubin level are indicators for

A

liver status

44
Q

When is BMP ordered?

A

blood glucose level, electrolyte and fluid balance, and kidney function

45
Q

When is CMP ordered

A

blood glucose level, electrolyte and fluid balance, kidney function, protein status, and liver function

46
Q

malnutrition type if there is no presence of inflammation

A

starvation related malnutrition

47
Q

malnutrition type if there is presence of inflammation mild to moderate degree

A

chronic disease or injury-related malnutrition

48
Q

malnutrition type if there is presence of high inflammation degree

A

acute disease or injury-related malnutrition (ICU)

49
Q

6 Characteristics of malnutrition

A

edema or fluid overload
significant weight loss
muscle wasting
fat wasting
decreased energy intake
reduced grip strength