Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

BI543—Pathogenic Microbiology > Exam 1 > Flashcards

Exam 1 Flashcards

1
Q

PRR for motile bacteria

A

TLR5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

PRR for dsRNA

A

TLR3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PRR for soluble teichoic/lipoteichoic proteins

A

c-reactive protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

PRR for foreign products in cytoplasm

A

NOD-like

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PRR for surface lipoprotein

A

TLR1/TLR2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

PRR for LPS

A

TLR4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

steps of infection

A

exposure
adherence
invasion
multiplication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Swine flu

pathogen
year
consequence

A

orthomyxovirus H1N1
1976
rushed & tainted vaccine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Legionnaire’s

pathogen
year
consequence

A

Legionella pneumophila
1976
CDC believed it was virus, ignored bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

AIDS
outbreak
earliest incidence

A

1981
1920

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

pathogenic E. coli strain

A

O157:H7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

3 food/waterborne diseases

A

Salmonella typhi
M. tuberculosis bovis
Clostridium botulinum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

endophytic
example

A

inside plants
E. coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

lung infections from contaminated mouthwash

A

Burkholderia cepacia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

wound/burn victims
cystic fibrosis patients
blue-green

A

Pseudomonas aeruginosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Iraq war vet infection
uses HGT

A

Acinetobacterium baumannii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

monitored by FoodNet

A

Campylobacter jejuni

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

monitors selected points in food production

A

Hazard Analysis & Critical Control Point program

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

vaginosis

A

shift from normal Lactobacillus to GN anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

8 skin defenses

A

dry, acidic environment
cooler than internal body
keratinized cells
desquamation (shedding cells)
sebum containing harmful compounds
commensals
SALT with WBCs
tight junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

skin commensals are mainly G__

22
Q

WBCs present in dermis

A

Langerhans

23
Q

Staph epidermidis on skin prevents…

A

colonization by Staph aureus

24
Q

4 mucosal defenses

A

mucus
defensins
antibodies
MALT

25
protectants present in mucus
lysozyme sIgA lactoferrin phospholipase A2
26
blackhead cause
sebum colonized by Propionibacterium acnes
27
whitehead cause
neutrophil activity
28
can survive for short periods in stomach lining, pH 4
E. coli Salmonella Campylobacter
29
major commensal in small intestine
Lactobacilli
30
major commensal in large intestine
Bacteroides
31
Complements ___ and ____ directs neutrophils to site of infection in extracellular matrix
C3a C5a
32
cause of bubonic plague
Yersinia pestis
33
c-reactive protein --> _______ pathway
classical
34
nodosome and inflammasome lead to ___________ of cell, which...
disintegration releases more cytokines
35
steps of a signalling cascade
Binding event Assembly of signaling complex Production of signal molecule (usually through phosphorylation) Activation of transcription factor
36
lysosome contents
antimicrobial peptides membrane permeabilizing proteins proteases phospholipases lysozyme defensins nitric oxide (NO) in very trace amounts
37
2 attacks in lysosome
macromolecule attack oxygen attack
38
oxygen attack reactions
superoxide H2O2 HOCl Fenton reaction
39
cat + organism
staph
40
Fenton reaction gives _______, which can...
hydroxide radical attack DNA
41
organisms that can live in phagosome or escape
M. tuberculosis/leprae Salmonella Rickettsia
42
used to fight organisms that persist in phagosome
autophagosome
43
4 cardinal signs
rubor -- redness tumor -- swelling calor -- heat dolor -- pain
44
5 main actions of complement
opsonization chemotaxis inflammation agglutination MAC
45
C5 -- C5a + C5b -- C6 + C7 -- C8 -- C9
MAC
46
__________ are GN bacteria can resist the MAC
serum-resistant
47
deficiency of MAC proteins increases susceptibility to
Neisseria
48
C1 + IgG -- C1r + C1s -- C2 + C4 -- C3b coating -- C5 and MAC
classical pathway
49
MBL -- C2 + C4 -- C2aC4b -- C3b fragments -- C4bC2aC3b -- C5 and MAC
lectin pathway
50
4 stages of septic shock
SIRS sepsis severe sepsis septic shock
51
main problem with septic shock
widespread vasodilation
52
specific major complication of septic shock
DIC

BI543—Pathogenic Microbiology (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions