Ex2 IAs Theories Flashcards
1
Q
MAC of volatile substance is inversely proportional to lipid solubility
A
Meyer-Overton hypothesis*
2
Q
In terms of Meyer-Overton hypothesis, high MAC = ______ potency
A
low*
3
Q
Potency correlates with lipophilicity
A
Meyer-Overton Hypothesis*
4
Q
Amnesia is from what?
A
probably not spinal cord mediated
5
Q
inhaled anesthetics act by effects at multiple sites
A
multiple theory of narcosis*
6
Q
anesthetics act on no more than 2-3 sites to produce a specific effect
A
Unitary Theory of Narcosis
7
Q
Anesthesia is produced by membrane bound protein intx in brain/spinal cord
A
Protein Based Mechanism
8
Q
Protein Based Mechanism
Brain
A
GABA-A
9
Q
Protein Based Mechanism
Spinal Cord
A
Glycine, NMDA, Na Channel
10
Q
MOA N2O
A
NMDA Antagonism
Potassium 2P-Channel stimulation
