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Pharm Fall 2019 > Ex2 Antbx > Flashcards

Ex2 Antbx Flashcards

1
Q

DOC MSSA

A

Nafcillin or oxacillin

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2
Q

Pt with MSSA has gram - growing

A

Cefazolin

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3
Q

Only cephalosporin that covers MRSA

A

Ceftaroline

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4
Q

Which drug class does not cover enterococcus at all?

A

Cephalosporins

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5
Q

Pt has PCN allergy. Needs skin flora coverage and gram -

A

Levofloxacin

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6
Q

Option for PNA

A

Levofloxacin

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7
Q

Levo/Cipro are not good option for

A

Invasive MRSA

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8
Q

DOC MRSA

A

Vancomycin

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9
Q

Pseudomonas coverage

A 
Zosyn
Ceftazidime
Carabenems (except ertapenem)
Aztreonam
Fluoroquinolones
Polymixin
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10
Q

Covers Cdiff

A

Metrondiazole

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11
Q

Covers MRSA, VRE, gram -, anaerobes

A

Tigecycline

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12
Q

Any operations above lungs, need anaerobe coverage

A

Clindamycin

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13
Q

Any operation below lungs that covers anaerobes

A

Metrondiazole

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14
Q

DOC for Nectrotizing fasciitis

A

Clindamycin

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15
Q

Which antbx can cause Cdiff?

A

Clindamycin

Levo/Cipro

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16
Q

Pt allergic to PCN/Beta Lactam, on Clinda, has gram - bacteria during head/neck op.

17
Q

Prolong QTc

A

Levo/Cipro
“Mycins”
Voriconazole

18
Q

Seizure risk in which medications?

A

Beta-lactams

19
Q

Agitation/hallucination is a risk in which medications?

A

Levo/Cipro

20
Q

How often are antibiotics re-dosed in the OR?

A

2x half life

21
Q

Example: how often is zosyn dosed in OR?

A

2x half life — normally q6; give q3 hours

22
Q

Skin flora coverage

23
Q

Skin flora coverage (PCN allergy)

A

Clindamycin or Vancomycin

24
Q

GI/GU procedure, DOC

A

Cefazolin + metronidazole

25
Q

GI/GU procedure, DOC (PCN allergy)

A

Aztreonam + metrondiazole +vancomycin

OR Levofloxacin + metrondiazole

26
Q

SSI definition

A

Within 30 days

Within 90 days if prosthetic placed

27
Q

DOC VRE

A

Daptomycin, Linezolid

28
Q

Enterococcus DOC

A

Ampicillin

29
Q

Enterococcus DOC; PCN allergy

A

Vancomycin

30
Q

Time dependent antibiotics

A

Penicillins, cephalosporins, carbapenems, aztreonam

31
Q

Concentration dependent antibiotics

A

Aminoglycosides, daptomycin, metronidazole

32
Q

AE Aminoglycosides

A

Renal dysfunction

33
Q

AE Beta Lactams

A

Seizures

Drug fever

34
Q

Increases risk of Cdiff

A

Fluoroquinolones

Clinda

35
Q

AE Fluoroquinolones

A

Agitation/hallucination

Prolonged QTc

36
Q

AE Linezolid

A 
MAOI Intxn (anything with serotonin increases risk SS)
Dec. Bone Marrow/platelets
37
Q

AE Flagyl

A

Dark urine- ok

38
Q

AE Polymixin

A

Acute neuromuscular blockade

Pharm Fall 2019 (33 decks)

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