Eukaryotic Cell Cycle - Mitosis and Cytokinesis in animal and plant cells Flashcards
Interphase and chromatin and chromosome
The first stage of the
eukaryotic cell cycle which involves cellular growth and duplication of
chromosomes.
Composed of three
phases: G1, S, and G2
Chromatin:
chromosomes
(DNA and proteins) that have
been unwound and loosely packed
during interphase
chromosome a structure
composed of DNA tightly wrapped
around histone proteins. Carries the genetic information (genes)
of a cell
Three sub-phases and the resting phase
- G1
- G0
- S
- G2
G1 phase
In the G1 phase, the cell grows by:
- increasing the volume of its cytosol
- synthesising proteins for DNA replication
- replicating its organelles.
G0 (resting phase)
Cells that are not required to replicate rest in the G0 phase.
Cells in G0 are either
quiescent or terminally differentiated.
Synthesis (S) phase
The cell replicates its DNA turning one chromosome into two genetically identical sister chromatids
After the S phase, each somatic cell
will still contain 46 chromosomes.
G2 Phase
The G2 phase is the final stage of interphase where the cell continues to grow and prepare
itself for mitosis. The G2 phase is similar to the G1 phase in that it involves:
- increasing the volume of the cytosol
- synthesising proteins in preparation for mitosis.
Quiescent dormant cells
Dormant cells which can re-enter the cell cycle
Terminally differentiated
Cells
that have fully specialised and no
longer replicate
Chromatid
One half of a double stranded
chromosome
Centromere
Holds sister chromatids together
Mitosis
The second stage of
the eukaryotic cell cycle, which
involves the complete separation
of sister chromatids and nuclei
Prophase
- Spindle fibres appear
- Chromosomes condense
- Breakdown of nuclear membrane
Spindle fibres
Move chromosomes to either pole of the cell during mitosis and meiosis
Metaphase
- Spindle fibres attach to chromosomes
- Chromosomes align along the equator
Anaphase
- Centromere divides
- Sister chromatids move to opposite poles
- Spindle fibres contract