Etc Flashcards
No Pee, No See, No Spit, No Shit + Tachycardia
Toxicity?
Anticholinergic Toxicity
- +Cutaneous vasodilation (red as a beet)
- +mad as a hatter (delirium)
- e.g. Diphenhydramine poisoning
- Tx: Physostigmine (cholinesterase inhibitor)
Tinnitus, N/V, Fever
Toxicity?
Salicylate Intoxication
- +AMS
- +Metabolic acidosis & Respiratory Alkalosis
- Tx: Sodium bicarbonate (alkalinization of urine)
House fire victim has this toxicity concern from combustion in closed spaces
Hydrogen Cyanide and Carbon Monoxide (CO)
- Cyanide poisoning Tx: Sodium Thiosulfate or hydroxocobalamin (B12) or Nitrites
- CO Poisoning Tx: 100% O2 or hyperbaric O2
Cyanide Poisoning. Tx?
- Sodium Thiosulfate
- Hydroxocobalamin (B12)
- Nitrites (to induce methemoglobinemia thru Fe3+ conversion, causing left shift)
Causes methemoglobinemia
Dapsone, Nitrates, Topical/local anesthetics
Lacrimation, bradycardia, miosis (constriction), salivation, diarrhea. Dx & Tx?
Organophosphate Poisoning
Tx: Atropine
Horizontal nystagmus, cerebellar ataxia, confusion. Toxicity?
Phenytoin toxicity
Tx: Supportive care
Acidosis + vision loss/blindness. Toxicity?
Methanol Poisoning
- Vision loss 2/2 optic disc hyperemia
- AGMA
- Tx: Supportive care
Pinkish-red skin hue or cherry lips
CO poisoning
Acetaminophen OD
- Activated charcoal (if <4 hrs)
- N-acetylcysteine
Caustic poisoning
- Necrosis, edema, scarring, and severe pain of GI tract
- Severe esophageal & stomach ulcerations
- Peritonitis, mediastinitis (if severe)
Garlic breath
Arsenic poisoning
- +Vomiting
- +Watery diarrhea
- +QTc prolongation
- +Hypo/hyperpigmentation
- +Hyperkeratosis
- +Stocking glove neuropathy
MJ intoxication effect on HR, RR, BP
Increased
(Tachycardia, Tachypnea, Hypertension)
- +Dry mouth
- +Conjunctival injection
- +Increased appetite
Opiate abuse/withdrawal Tx:
MSNBC
- Methadone
- Suboxone/Subutex
- Naloxone/Naltrexone: partial agonist & antagonist respectively
- Buprenorphine (partial agonist)
- Clonidine
Alcohol Abuse Tx:
NAAT:
- Naltrexone (antagonist)
- Acamprosate
- Antabuse (disulfiram)
- Topiramate (anticonvulsant)
Ethylene Glycol poisoning Tx
Fomepizole or Ethanol
(to inhibit alcohol dehydrogenase)
- Presentation: Hypocalcemia, Calcium oxalate deposition
Hypotension + Dilated pupils + QRS Prolongation. Toxicity?
TCA Overdose
Tx: Sodium bicarbonate
(treats cardiotoxicity affecting myocyte sodium channels)
Aspirin + asthma
ASA-exacerbated respiratory disease (AERD)
ASA and ß-blockers can trigger bronchoconstriction in asthmatics, especially those with chronic rhinositis and/or nasal polyps
Systolic-diastolic abdominal bruit
Renal Artery Stenosis
(RAS)
Bruit is 2/2 renovascular HTN
- +Resistant HTN (_>_3 drugs)
- +Severe HTN (>180/120)
- +Malignant HTN (end-organ damage)
- +Diffuse atherosclerosis
Whenever we want to treat HTN in conjunction with DM, ____ are the best Rx option because they are ____.
ACE-I; rebal protective
Type of IVF preferred for volume resuscitation of burn victims
Lactated Ringer solution (LR)
- Isotonic crystalloid solution that is a balanced fluid w/ near-physiologic levels of chloride, potassium, and calcium, including sodium lactate, a buffer that is hepatically metabolized to bicarbonate, which helps correct acidosis and maintain normal blood pH
- Normal Saline (0.9% Saline) is considered an unbalanced fluid bc its chloride concentration is supraphysiologic (154 vs 103 mmol/L) and can cause a hyperchloremic metabolic acidosis; has also been a/w hypocoagulability
- Half-Normal Saline (0.45% Saline) is used as a maintenance fluid and should be infused slowly because it is hypotonic (lower osmolality than blood).
Type of IVF preferred for volume resuscitation of burn victims
Lactated Ringer solution (LR)
- Isotonic crystalloid solution that is a balanced fluid w/ near-physiologic levels of chloride, potassium, and calcium, including sodium lactate, a buffer that is hepatically metabolized to bicarbonate, which helps correct acidosis and maintain normal blood pH
- Normal Saline (0.9% Saline) is considered an unbalanced fluid bc its chloride concentration is supraphysiologic (154 vs 103 mmol/L) and can cause a hyperchloremic metabolic acidosis; has also been a/w hypocoagulability
- Half-Normal Saline (0.45% Saline) is used as a maintenance fluid and should be infused slowly because it is hypotonic (lower osmolality than blood).