Cardiology Flashcards
Electrical alternans
Pericardial effusion
(2/2 pericarditis, MI, penetrating trauma, iatrogenic [Central-line placement, pacemaker insertion])
New-onset RBBB
Right heart strain
(think PE; usually +JVD)
Symmetric ischemia and necrosis of distal fingers/toes during vasopressor resuscitation
NE-induced vasospasm
Can also occur in intestines and kidneys
(mesenteric ischemia; renal failure)
Fingertip pain and pallor triggered by cold or stress
Raynaud’s phenomenon
Asymmetrical “blue toe syndrome”
cholesterol emboli
(pts with atherosclerosis)
Immigrant + irregular heartbeat
Rheumatic MS
Fainting after urinating, coughing, or defecating
Situational syncope
(triggers cause a cardioinhibitory, vasodepressor,
or mixed neural alteration in autonomic response)
Postural change-induced fainting
Orthostatic syncope
Fainting from prolonged standing, emotional distress, or painful stimuli
Vasovagal syncope
(neurally mediated)
- Tx: Counterpressure maneuvers & trigger avoidance
- e.g. leg crossing w/ tensing of muscles, handgrip, tensing of arm muscles w/ clenched fists, etc.
Exercise-induced fainting
- HOCM
- Aortic stenosis
- Anomalous coronary arteries
Fainting w/ prior hx of CAD, MI, cardiomyopathy,
or decreased EF
Ventricular arrhythmias
Fainting in setting of sinus pauses, prolonged PR or prolonged QRS
Sick sinus syndrome, bradyarrhythmias, or AV block
Fainting in setting of hypokalemia, hypomag, increased QT meds
Torsades de points
(acquired long QT syndrome)
FHx of sudden death, increased QT, syncope w/ exercise/startle/sleeping
Congenital long QT syndrome
Micturition
Urination
Upper extremity HTN + lower extremity claudication
Aortic coarctation
Dilated pupils
Cocaine/stimulants
Pinpoint pupils
Heroin/Opioids
Avoid ___ in cocaine-induced ACS
Beta Blockers
(to avoid risk of unopposed cocaine-induced alpha agonist activity and resultant worsening vasoconstriction)
Digitalis (Digoxin) toxicity
CGN
Digoxin
Cardiac Glycoside
- Cardiac (Atrial tachycardia with AV block)
- GI (anorexia, N/V, abd pain)
- Neurologic (fatigue, confusion, weakness, color vision alterations)
- Increased ectopy in atria or ventricles —> Atrial tachycardia
- Increased vagal tone —> Decreased AV node conduction —> Potential AV block
- Increased with amiodarone
Pulsus paradoxus
Cardiac tamponade or severe asthma/COPD
(Respiratory variation in SBP)
>10mmHg SBP drop during inspiration
Pulsus paradoxus
(Cardiac tamponade or severe asthma/COPD)
Post-CABG
Think cardiac tamponade ⇒ get echo
Most common location of ectopic foci
that cause AFib
Pulmonary veins
(can be disrupted by catheter-based radiofrequency ablation)
S3
CHF or Volume Overload:
- CHF
- MR (chronic severe)
- AR (chronic)
- Pregnancy (due to high CO state)
- Thyrotoxicosis (due to high CO state)
S4
“HHAA”
- HTN
- HOCM
- Aortic Stenosis
- Acute MI
PCWP
LA pressure; LV End-Diastolic pressure
- Decreased in intravascular volume loss
Increased BNP
CHF
- +S3 sound
- +/- peripheral edema (less specific for CHF)
Arrhythmia caused by hypokalemia and hypomagnesemia
VT
(such as with furosemide)
Tx of beta blocker or CCB toxicity
IV Atropine + IVF
(IV Glucagon if refractory)
Prolonged PR interval, normal QRS
First-degree AV block due to delayed impulse transmission anywhere from atria to ventricles —> NO FURTHER EVALUATION REQUIRED
(Observation only)
Prolonged PR + wide QRS duration
Conduction delay likely below the AV node
(often in bundle branches) —> Electrophysiological testing
Causes of HFpEF
- Dilated cardiomyopathy (beriberi/thiamine deficiency)
- Hypertrophic cardiomyopathy
- Restrictive cardiomyopathy (sarcoidosis, amyloidosis, hemochromatosis, endomyocardial fibrosis)
Lid lag
hyperthyroidism
Wt loss + lid lag + hand tremor
hyperthyroidism
Indication for Holter monitoring
Symptomatic pts w/ intermittent arrhythmias
CHF (diastolic dysfxn) + proteinuria + easy bruising
Amyloidosis
(in elderly)
AL amyloidosis
primary
AA amyloidosis
secondary to RA, IBD, chronic infections
Systolic murmur that increases on inspiration in IV drug user
Tricuspid valve endocarditis
HF w/ hx of cardiac surgery or radiation
Constrictive pericarditis
Mid-diastolic sound - Pericardial knock
constrictive pericarditis
Pericardial calcifications on echo
constrictive pericarditis
Post-MI acute limb ischemia
Arterial embolus from LV thrombus
Tx:
- IMMEDIATE ANTICOAGULATION
- Echo to look for LV thrombus & fxn
- Vascular surgery consult
Hepatojugular Reflux (JVP >3cm w/ abd compression)
RV Failure
Avoid in RVMI
Nitrates, Diuretics, Opioids
Due to high sensitivity of RV to intravascular volume depletion leading to profound hypotension (cardiogenic shock) —> Tx: Isotonic saline bolus
Upturning of cardiac apex on CXR
TOF
(RVH 2/2 pulmonic stenosis—“boot-shaped” heart)
Displacement of tricuspid valve w/ enlarged RA
Ebstein anomaly
Scoliosis + coarctation
Turner syndrome (XO)
Rib notching on CXR
Coarctation of Aorta
(2/2 dilated intercostal arteries)
“3” sign on L costal surface in CXR
Coarctation of aorta
(Aortic knob —> Actual coarctation —> Post-stenotic dilation of aorta)
2:1 AST/ALT
Alcoholism
Wheals
urticaria (allergy or anaphylaxis)
Long bone fx + dyspnea, neurological sx, & petechial rash 12-24 hours post-injury
Fat embolism
Systolic murmur @ apex that radiates to axilla
MR
Short PR
WPW
- “Ventricular pre-excitation syndrome”
- Accessory AV conduction pathway not contained within the AV node may cause a short PR interval & a delta wave (slurred upward sloping of QRS due to pre-excitation) on EKG
- AFib w/ WPW has increased risk of VF →
- Stable: Procainamide
- Unstable: Synchronized Cardioversion (DC)
Tx for 3rd degree (complete) heart block
Temporary cardiac pacing
S4
HHA: HTN, HOCM, Aortic Stenosis
Hyperthermia/HIGH fever post-syncope
Exertional heat stroke
Exertional heat stroke Tx
ICE-WATER IMMERSION
Nonexertional heat stroke (elderly) Tx
EVAPORATIVE COOLING MEASURES
Cyproheptadine
Serotonin antagonist used in serotonin syndrome if discontinuation + supportive measures fail.
Anterior MI post-MI complication
think Free Wall Rupture (LAD) hours-14d
Inferior MI post-MI complication
think Papillary Muscle Rupture (RCA) 2d-7d
Anterior/Posterior MI post-MI complication w/ RHF
Interventricular Septum Rupture
(LAD or RCA) 0-5d
Inhibits TXA2 production
ASA
Anti-inflammatory that inhibits mitosis and neutrophil activity
Colchicine
(gout, pericarditis, Behcet’s)
PEA
—> CPR + q4 Epi
Asystole
—> CPR + q4 Epi
VF
—> Defibrillation + q2 Epi/Amiodarone
Pulseless VT
—> Defibrillation + q2 Epi/Amiodarone
Chest Pain DDx
Cardiac/Pulm/GERD/MSK/Psychogenic/Thyrotox/
Drugs/Pheo/VZV
Pulm - PE/PTX/PNA
Pleuritic Chest Pain (PPPC)
Pericarditis, PTX, PE, Costochondritis (MSK)
Palpable thrill at suprasternal notch
AS
Bounding pulses
—> AR
(+”pounding” heart/heartbeat awareness)
“Pounding” heart/Heartbeat awareness
AR due to chamber enlargement and myocardial hypertrophy from AR-induced increase in LVEDV, bringing ventricular apex close to chest wall;
(or can be from palpitations from AFib)
Peripheral edema side-effect
Amlodipine (CCBs)
- Especially dihydropyridines—amlodipine, nifedipine—due to systemic vasodilation
Post-MI Blue toe syndrome
Cholesterol embolism
(atheroembolism) - common complication following cardiac catheterization
CYP450 Inhibitors
(Increase Warfarin effect; increase bleeding risk)
AAA RACKS IN GQ Magazine
- Acute Alcohol Abuse
- Acetaminophen
- Ritonavir
- Amiodarone
- Cimetidine/ciprofloxacin - Antibiotics
- Ketoconazole -antifungal
- Sulfonamides - Antibiotics
- INH
- Grapefruit juice/Cranberry juice
- Quinidine
-
Macrolides (except azithromycin) - Antibiotics
- Omeprazole
- Thyroid hormone
- SSRIs (e.g. fluoxetine
CYP450 Inducers
(Decrease Warfarin effect; decrease bleeding risk):
Chronic Alcoholics Steal Phen-Phen &
Never Refuse Greasy Carbs
- Chronic alcohol use
- St. John’s wort, Ginseng
- Phenytoin
- Phenobarbital
- Nevirapine
- Rifampin
- Griseofulvin
- Carbamazepine OCPs
Acetaminophen + Warfarin
Increased bleeding
(CYP450 inhibitor)
Theophylline toxicity
CGN
(like digoxin toxicity)
- Cardiac (arrhythmias)
- GI (N/V)
- Neuro (CNS Stimulation: HA, insomnia, seizures)
- CYP450 metabolism; Narrow therapeutic index
Pounding heartbeat sensation in L lateral decubitus position
AR 2/2 LV enlargement
Wide pulse pressure
AR
Post-cardiac cath AKI
Cholesterol emboli vs. CIN (contrast-induced nephropathy)
- CIN resolves within 3-5d
- Cholesterol emboli can be immediate or delayed >30d
Rheumatic Heart Disease causes AFib due to
Mitral stenosis-induced LA dilation
Torsades de pointes Tx
- IV Magnesium (stable)
- Defibrillation (unstable)
Subauricular bruit
FMD
- Dx: Duplex US or CTA/MRA
- Tx: ACE/ARBs, PRTA, or surgery
Meds that can trigger bronchoconstriction in
asthma pts
ASA & BBs
Tx for Torsades de pointes
IV Magnesium
Tx of bradycardia associated with hypothermia
Active external rewarming + warmed IV fluids
(refractory to atropine or cardiac pacing during hypothermia)
Post-MI complication up to 3 months out
- Pericarditis (1 d-3mo)
- LV aneurysm (5d-3mo)
Systolic-diastolic abdominal bruit in pt with HTN
Renal Artery Stenosis (RAS)
(Renovascular Hypertension)
- Can be heard in ~40% of RAS pts
- Other clues: Malignant HTN, Resistant HTN, Severe HTN w/ diffuse atherosclerosis
- +unexplained atrophic kidney
- +recurrent flash pulmonary edema
- +unexplained rise in Cr following ACE-I or ARB
- Dx: Renal doppler, CT angiography, or MR angiography
Why does PCWP ↑ in MI?
Failure of Forward Blood Flow
PCWP = Estimate of LA Pressure
Failure of ______ to close is PDA
Ductus Arteriosus
____ closes PDA; ____ opens PDA
NSAIDs close PDAs
Prostaglandins keep open PDAs
Interventricular calcifications
Congenital CMV
Periventricular Calcifications at birth
Toxoplasma
Cholesterol Screening (Lipid Panel)
Every 3-5 years beginning at age 40