Erysipelothrix Flashcards

1
Q

Erysipelothrix Rhusiopathiae is gram _____, ____ acid fast and ____ spore forming

A

gram positive

non acid fast

non spore forming

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2
Q

Erysipelothrix rhusiopathiae is catalase _____, oxidase ____ and coagulase_____

A

catalse negative

oxidase negative

COAGULASE POSITIVE

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3
Q

Erysipelothrix rhusiopathiae produces a ____ that allows for intracellular survival as well as survival in the environment

A

Capsule

antiphagocytic

prolongs survival in phagolysosome

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4
Q

What is the most common speices affected in Erysipelothrix rhusiopathiae

A

Swine- important to the swine industry

pigs less than 3 month and over 3 years are LESS susceptible

mainly in production animals due to the stress associated with the production

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5
Q

Erysipelothrix Rhusiopathiae is more opportunistic in _____ and ____

A

turkey and sheep

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6
Q

What is the most important virulence factor of Erysipelothrix?

A

Neurominidase

-cleaves sialic acid and allows the bacteria to adhere

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7
Q

Erysipelothrix is resistant to _____

A

drying

survive up to 6 months in swine feces

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8
Q

True/False: Erysipelothrix is highly variable

A

True! over 23 serotypes. VERY VARIABLE

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9
Q

Erysipelothrix is part of the common flora on the skin surface of ___

A

fish

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10
Q

How is this bacteria transmitted?

A

ingestion mainly of contaminated material

wound infections/ arthropod bites

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11
Q

Pathogensis of Erysipelothrix

A
  1. bacteria is exposed and capsule and neurominidase is expressed to allow for survival in phagocytes
  2. Start binding to endothelium- vascular damage and thrombus
  3. survival inside phagocytes
  4. If not taken in, can disseminated and cause septicemia. important in heart and joints and you can see endocarditis
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12
Q

True/ False: causes low mortality in swine

A

False: causes HIGH mortality rates in swine

mainly due to septic form

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13
Q

What are some clinical signs in swine?

A

fever, anorexia, reluctance to walk, vomiting ect

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14
Q

Swine develop _____ skin disease which is very common and seldom results in mortality

A

Diamond

due to antibody-antigen complexes

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15
Q

What is the most common treatment during the acute phase?

A

Penicillin

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16
Q

What can the chronic from of Erysipelothrix lead to?

A

endocarditis

arhritis - presence of bacteria in the joint tissue

17
Q

What does Erysipelothrix normally cause in birds (mainly turkeys)

A

septicemia

swollen cyanotic snood

mortality 2-25%

18
Q

What is the main presentation in sheep with Erysipelothrix?

A

Polyarthritis

19
Q

In what humans is Erysipelothrix most common?

A

fish handlers

20
Q

Best immunologic response is cell mediated and humoral directed to ______

A

neurminidase

21
Q

vaccines are effective against the ____ form of Erysipelothrix

A

acute- use penicillin

Penicilin can be used for both Swine and turkeys

22
Q

what type of culture should you use for Erysipelothrix?

A

Blood culture in CO2

usually non hemolytic

23
Q

Erysipelothrix causes gram positive slender ____

A

rods

24
Q

Erysipelothrix in culture produces _____

A

hydrogen sulfide

25
Q

How to prevent Erysipleothrix

A

reduce stress

good sanitation and nutrition

prevent fighting of turkeys