Erysipelothrix Flashcards
Erysipelothrix Rhusiopathiae is gram _____, ____ acid fast and ____ spore forming
gram positive
non acid fast
non spore forming
Erysipelothrix rhusiopathiae is catalase _____, oxidase ____ and coagulase_____
catalse negative
oxidase negative
COAGULASE POSITIVE
Erysipelothrix rhusiopathiae produces a ____ that allows for intracellular survival as well as survival in the environment
Capsule
antiphagocytic
prolongs survival in phagolysosome
What is the most common speices affected in Erysipelothrix rhusiopathiae
Swine- important to the swine industry
pigs less than 3 month and over 3 years are LESS susceptible
mainly in production animals due to the stress associated with the production
Erysipelothrix Rhusiopathiae is more opportunistic in _____ and ____
turkey and sheep
What is the most important virulence factor of Erysipelothrix?
Neurominidase
-cleaves sialic acid and allows the bacteria to adhere
Erysipelothrix is resistant to _____
drying
survive up to 6 months in swine feces
True/False: Erysipelothrix is highly variable
True! over 23 serotypes. VERY VARIABLE
Erysipelothrix is part of the common flora on the skin surface of ___
fish
How is this bacteria transmitted?
ingestion mainly of contaminated material
wound infections/ arthropod bites
Pathogensis of Erysipelothrix
- bacteria is exposed and capsule and neurominidase is expressed to allow for survival in phagocytes
- Start binding to endothelium- vascular damage and thrombus
- survival inside phagocytes
- If not taken in, can disseminated and cause septicemia. important in heart and joints and you can see endocarditis
True/ False: causes low mortality in swine
False: causes HIGH mortality rates in swine
mainly due to septic form
What are some clinical signs in swine?
fever, anorexia, reluctance to walk, vomiting ect
Swine develop _____ skin disease which is very common and seldom results in mortality
Diamond
due to antibody-antigen complexes
What is the most common treatment during the acute phase?
Penicillin
What can the chronic from of Erysipelothrix lead to?
endocarditis
arhritis - presence of bacteria in the joint tissue
What does Erysipelothrix normally cause in birds (mainly turkeys)
septicemia
swollen cyanotic snood
mortality 2-25%
What is the main presentation in sheep with Erysipelothrix?
Polyarthritis
In what humans is Erysipelothrix most common?
fish handlers
Best immunologic response is cell mediated and humoral directed to ______
neurminidase
vaccines are effective against the ____ form of Erysipelothrix
acute- use penicillin
Penicilin can be used for both Swine and turkeys
what type of culture should you use for Erysipelothrix?
Blood culture in CO2
usually non hemolytic
Erysipelothrix causes gram positive slender ____
rods
Erysipelothrix in culture produces _____
hydrogen sulfide
How to prevent Erysipleothrix
reduce stress
good sanitation and nutrition
prevent fighting of turkeys
