Erectile Dysfunction Flashcards
arteries in the cavernosum are?
cavernosal artery
what main artery supplies the pelvic structures?
internal iliac
what main artery supplies penis
internal pudendal
arteries of penis
dorsal artery
cavernosal arteries
important vein for penis?
deep dorsal vein, and drains near prostate
subtunical veins do what during erection?
compressed and stop drainage
parasympathetic origin and exit?
brainstem with vagus
S2-4
sympathetic origin?
thoracolumbar: T1-L1-2
physiology of erections
psycho, emo, physical neuro arterial change venous compression structural
vessels and muscles do what in erection?
trapping of blood in sinusoids via compression of subtunical venous plexus
contraction of ischiocavernous muscles
erectile dysfunction prevalence?
50% of men aged 40-70
risk factors for erectile dysfunction
psychiatric MEDS CVD genito-urinary SES: lower socioeconomic Chronic disease
2 broad categories of erectile dysfunction?
psychogenic
organic
causes of organic erectile dysfunction?
vascular
neurogenic (diabetes, iatrogenic)
anatomic
endocrinologic
Neurogenic causes of erectile dysfunction?
central (MS, parkinson’s)
spinal cord
Peripheral
alcohol
diabetes
3 causes of arteriogenic erectile dysfunction?
CVD
iatrogenic
pelvic trauma
what drugs/substances cause erectile dysfunction?
smoking alcohol antihypertensives psychiatric meds androgen deprivations
testosterone lab sample contains?
Free+total
SHBG/albumin
treatment of erectile dysfunction?
treat any underlying CVD or other disease
try PDE5 inhibitors
most common SFx with sildenafil?
headache, but if persist then headache is less
PDE5 contraindications
nitrates (veno dilatation)
caution with alpha-blockers
can you take antihypertensives with PDE5 inhibitors?
yes, safe.
second line therapy for erectile dysfunction?
direct intracavernosum injections
penis pumps
intra cavernosum cylinders
how many cavernosum vs. spongiosum?
2 cavernosum 1 spongiosum (urethra in it)
