Androgen Deficiency in Men Flashcards
symptoms of decreased testosterone
reduced muscle mass
osteoporosis
increased fat mass
hynaecomastia
testosterone diurnal when?
higher in morning, spontaneous erections
what happens if you get a low testosterone test?
need repeat test before treatment
increased SHBG symtoms?
aging cirrhosis hyperthyroid anticonvulsants infection estrogens
decreased SHBG symptoms?
nephrotic syndrome
obesity
hypothyroid
use of glucocorticoids
hyperprolactinaemia in men manifests?
low libido because switches off testosterone
how does klinfelters present?
low IQ
disruptive/behavioural
karyotype and prevalence of klinefelters?
1:660
47, XXY
effects of testosterone replacement?
increase bone mineral density more muscle more energy and sexual function more haemoglobin increased prostate volume
why is oral testosterone not really used?
metabolized by liver, get abnormal LFTs
contraindications to testosterone replacement therapy
prostate cancer PSA DRE male breast cancer erythrocytosis UTIs OSA desire to have child
adverse effects of testosterone replacement
erythrocytosis
acne, oily skin
prostate cancer
reduced sperm production
do you need testosterone for erections?
Nope. Just low libido.
Will loose morning erection
