Chronic Kidney Disease Flashcards
how to measure GFR?
IV Inulin
radiolabelled substances
- creatinine, cystatin C (endogenous)
why is serum creatinine not the best to use? how to fix it?
related to muscle mass.
24 urine measures (creatinine clearance)
you can lose 50% GFR and not have a change in creatinine
when not to use eGFR?
acute kidney injury
define CKD
GFR 3 months with or without evidence of kidney damage
risks factors for chronic kidney disease?
smoker dm2 HTN obesity CVD FHx aboriginal
what ratio use for CKD detection?
albumin to creatinine ratio
calcium in CKD?
down
phosphate in CKD?
goes up
Hba1c in CKD?
Hba1c declines
PCKD inheritance?
autosomal dominant
general Rx principles of CKD?
avoid nephrotoxic meds
keep BP under control
most common adult nephropathy?
IgA nephropathy
BP targets in CKD?
Who has normally high creatinine?
body builders
high protein
