Equine bacterial respiratory disease Flashcards

1
Q

Which bacteria causes strangles?

A

Streptococcus equi equi

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2
Q

Streptococcus is a bacterial respiratory disease mainly affecting which 2 areas?

A

Upper respiratory tract

Lymph nodes of head

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3
Q

What are the clinical signs of Streptococcus equi equi?

A
Pyrexia (fever), dull, inappetent
Inflammatory changes on blood sample
Nasal discharge 
Lethargy
Abscessation
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4
Q

In a severe case of strangles what can occur?

A

Dyspnoea (laboured breathing)

  • pharyngeal compression
  • tracheotomy required
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5
Q

What is bastard strangles?

A

Complication

  • Transient bacteremia
  • Abscesses can form in other tissues and lymph nodes
  • Disseminated abscesses difficult to treat (spread throughout body)
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6
Q

What are the characteristic features of Streptococcus equi var. equi bacteria?

A
Gram positive
Cocci
Pairs/chains
Facultative anaerobe 
Hyaluronic acid capsule 
Lactose fermentation negative
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7
Q

On the Streptococcus equi var. equi structure, what is the target for vaccines?

A

M-protein on the cell wall

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8
Q

How is Streptococcus equi var. equi spread? How well adapted to the environment is it?

A
  • Highly contagious: spread by direct contact and fomites
  • Sensitive to sunlight and heat
  • Sensitive to most disinfectants
  • Survives in environment for up to 4 weeks
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9
Q

Rate of Streptococcus equi var. equi increase with…?

A
  • Increasing group size
  • Increasing horse movement
  • Increased mixing of horses
  • Communal feeders and drinkers
  • Younger horses
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10
Q

What are the two methods of confirming a horse is free from a Strangles infection?

A
  1. Guttural pouch wash - 1 negative result

2. 3 negative nasal swabs each week for 3 weeks

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11
Q

In an outbreak what do red, amber and green areas refer to?

A
Red = Confirmed cases
Amber = Been in contact with confirmed cases
Green = No contact with confirmed cases
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12
Q

In a disease outbreak when can a yeard open again?

A

When all horses are declared ‘free of disease’

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13
Q

Which bacteria causes Rattles?

A

Rhodococcus equi

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14
Q

What are the acute signs of Rhodococcus equi infection?

A
  • Affects young foals

- Fever, anorexia, cough, nasal discharge

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15
Q

What are the chronic signs of Rhodococcus equi infection?

A
  • Affects older foals

- Cough, dyspnoea, weight loss, exercise intolerance, loud crackles on auscultation

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16
Q

Where does Rhodococcus equi multiple to spread infection in the body?

A

Alveolar macrophages

17
Q

Which anatomical structures are destroyed by Rhodococcus equi as abscesses form?

A
  • Alveoli in lungs

- Peyer’s patches in gut

18
Q

What are Rhodococcus equis virulence factors?

A
  • Polysaccharide lipid rich capsule inhibits phagocytosis
  • Intracellular pathogen due to inhibitory cell surface antigens
  • Antigens encoded by VAP plasmid & only expressed at 34-41 degrees
19
Q

How is Rhodococcus transmitted?

A
  • Inhaled: affects cranial right lung first

- Oral route

20
Q

How can Rhodococcus equi be prevented/controlled?

A
  • Long term antimicrobials
  • Avoid crowding and remove foal manure
  • Reduce dust
  • No vaccine
  • Examine foals closely twice a week until 4 months old
  • Won’t eradicate from environment