Canine viral infections Flashcards
What classification of virus is canine distemper virus?
RNA virus with an envelope
Describe the pathogenesis of canine distemper virus
- Oronasal infection
- Multiples in lymphoid tissues of the respiratory tract
- Spreads to lymph, bone marrow and spleen
- Further spread to epithelial and CNS tissues
What are the clinical signs of canine distemper virus?
- Anorexia, pyrexia, depression
- Coughing
- Nasal and ocular discharge
- Vomiting and diarrhoea
How can canine distemper virus be diagnosed?
RT-PCR - smears, blood, urine, sediment
When is canine distemper virus vaccinated against?
When MDA declines to non-detectable levels, around 8-12 weeks
Compare canine adenovirus 1 and 2
CAV-1: systemic disease that can also cause upper respiratory tract disease
CAV-2: Respiratory disease
Infectious canine hepatitis is caused by which type of canine adenovirus?
CAV-1
What are the clinical signs of infectious canine hepatitis?
- pyrexia, depression, lethargy
- vomiting and diarrhoea
- coughing
- abdominal pain
How can infectious canine hepatitis be diagnosed?
- Virus isolation from faecal samples or oropharyngeal swabs
- Serology
Which type of canine adenovirus has an effective vaccination?
CAV-2
Canine parvovirus attacks which types of cell?
Rapidly dividing
What class of virus is canine parvovirus?
Non-enveloped DNA virus
Describe the pathogenesis of canine parvovirus
- Faecal-oral transmission
- Virus replicated in lymphoid tissue
- Viraemia
- Destruction of normal GI epithelium
What are the clinical signs of canine parvovirus?
o More severe in young rapidly growing pups (<12wks)
o Inapparent infection to sudden death
o Range of gastrointestinal signs – vomiting, diarrhoea (haemorrhagic)
o Anorexia, depression, pyrexia
o Dehydration
o Sepsis and DIC
Is there a vaccination for canine parvovirus?
Yes
