Antivirals Flashcards

1
Q

Where are interferon alpha and beta produced from?

A

Virally infected cells

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2
Q

Where is interferon gamma produced from?

A

Activated lymphocytes

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3
Q

What is the role of interferons?

A

They generate antiviral resistance in uninfected tissue cells and recruit immune cells (signal)

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4
Q

How are interferons switched on?

A

When RNA replicates in viral cells

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5
Q

An oral low dose of human alpha interferon was used to treat what 3 conditions in small animals?

A

FIV
FeLV
Canine parvovirus

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6
Q

What are the 4 clinical signs of FeLV?

A

Reproductive disease
Anaemia
Immunodeficiency
Neoplasia

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