Antivirals Flashcards
1
Q
Where are interferon alpha and beta produced from?
A
Virally infected cells
2
Q
Where is interferon gamma produced from?
A
Activated lymphocytes
3
Q
What is the role of interferons?
A
They generate antiviral resistance in uninfected tissue cells and recruit immune cells (signal)
4
Q
How are interferons switched on?
A
When RNA replicates in viral cells
5
Q
An oral low dose of human alpha interferon was used to treat what 3 conditions in small animals?
A
FIV
FeLV
Canine parvovirus
6
Q
What are the 4 clinical signs of FeLV?
A
Reproductive disease
Anaemia
Immunodeficiency
Neoplasia