Equations Flashcards

1
Q

Altitude effect on PaO2

A

(Barometric pressure 1-47)(FiO2) =(barometric pressure 2-47 (FiO2)

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2
Q

A-A gradient (pAO2-paO2)

A

[FiO2x (barometric pressure-47)- (paCO2/0.8)] -paO2

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3
Q

Alveolar minute ventilation

A

(TV-dead space) x RR

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4
Q

Anion gap

A

NA - (cl + bicarb)

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5
Q

Cardiac output

A

HR x SV

SBP/ total peripheral vascular resistance

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6
Q

Cerebral blood flow

A

Cerebral perfusion pressure /cerebral vascular resistance

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7
Q

Cerebral perfusion pressure

A

Mean arterial pressure- intracranial pressure

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8
Q

Conpliance

A

Change in Volume /change in pressure

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9
Q

Physiologic dead space (Bohr)

A

[(Arterial CO2 -expired CO2)/arterial CO2] x TV

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10
Q

Elastance

A

Change in pressure/change in volume

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11
Q

FENa or urinary fractional secretion or Na:

A

[Urine Na] x [plasma creatinine] /
[urine creatinine] x [plasma Na]

X100

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12
Q

Laminar flow

A

Change in pressure /Resistance

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13
Q

Resistance

A

8 x viscosity x length / pie x radius^4

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14
Q

Glomerular filtration rate

A

0.45 x height (cm) / plasma creatinine

(For premature infants use 0.33 instead of 0.45)

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15
Q

Hardy Weingburg equilibrium

A

P + q =1

P^2 + 2pq + q^2 = 1

P = population frequency of dominant allele
q = population frequency of recessive allele

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16
Q

Henderson- Hasselbach equation

A

[H+] = 24 x CO2 / bicarbonate

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17
Q

Laplace law

A

Distending pressure = 2 x surface tension/ radius

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18
Q

Mean Airway Pressure

A

K (PIP-PEEP) x [i-time / (I-time + e-time)] + peep

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19
Q

Minute ventilation

A

TV x RR

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20
Q

Osmolality

A

2(plasma Na) + (glucose/18) + (BUN/2.8)

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21
Q

O2 content of blood

A

[1.34 x Hb x O2 sat] + [0.003 x PaO2]

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22
Q

Oxygen consumption (Fick principle)

A

CO x (arterial O2 content - venous O2 content)
CO x (1.34) x Hb x (arterial O2 Sat -venous O2 Sat)

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23
Q

Oxygen delivery

A

Cardiac output x O2 content

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24
Q

Oxygenation index

A

MAP x FiO2 (full like 100)/
PaO2

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25
Q

Ponderal index

A

Weight (grams)/
(Crown-heel^3)
X100

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26
Q

Power

A

Work x frequency

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27
Q

Pulmonary to systemic blood flow ratio

A

Aorta O2 Sat - superior vena cava O2 Sat/
Pulm venous O2 Sat- pulm artery O2 sat

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28
Q

Pulmonary vascular resistance

A

Mean pulmonary pressure - mean left atrial pressure /
Pulmonary blood flow

29
Q

Renal clearance

A

Urinary concentration of solute x (urinary volume/ length of time collected)/
Plasma concentration of solute

30
Q

Resistance

A

Change in pressure /change in flow

31
Q

Saturation level for cyanosis

A

HbO2/
Reduced Hb + HbO2

32
Q

Shortening fraction

A

LV diastolic dimension- LV systolic dimension /
LV diastolic dimension

x 100

33
Q

Intrapulmonary shunt equation

A

O2 content pulm cap- O2 content systemic art/
O2 content pulm cap- O2 content mixed venous

34
Q

Systemic vascular resistance

A

Mean aortic pressure -mean right atrial pressure / systemic blood flow

35
Q

Na deficit

A

Na desired -Na current x 0.6 x weight

36
Q

Time constant

A

Resistance x Conpliance

37
Q

Work of breathing

A

Pressure x volume

38
Q

Clearance of drug

A

Elimination rate constant x volume of distribution

39
Q

Elimination half life

A

0.693 x Vd/
Clearance of drug

40
Q

Elimination rate constant

A

Clearance of drug /
Volume or distribution

41
Q

Loading dose

A

Volume of distribution x plasma concentration/
Fraction of drug which is active x fraction of drug which is bioavailable

42
Q

Steady state concentration

A

Infusion rate /
Volume of distribution x elimination rate constant

43
Q

Volume of distribution

A

Total amount of drug in body/
Plasma concentration of drug x weight

44
Q

Attributable risk or risk difference

A

[A/a+b ] - [c/c+d]

45
Q

Attributable risk%

A

Attributable risk / [a/ (a+b)]
X 100

46
Q

False negative

A

1- sensitivity

47
Q

False positive

A

1- specificity

48
Q

Incidence cumulative

A

of new cases of disease in a given time period/ total population at risk

49
Q

Incidence rate

A

of new cases of disease in a give time period / person-time years of observation

50
Q

Positive likelihood ratio

A

Sensitive / (1- specificity)

51
Q

Negative likelihood

A

(1-sensitivity) / specificity

52
Q

Mean

A

Sun of observations/ # of observations

53
Q

Mortality rate , BW

A

Deaths in a specific BW category /
# of births in same BW category x 100

54
Q

Mortality rate fetal

A

Fetal deaths /
Live births + fetal deaths

X100

55
Q

Mortality rate infant

A

Infant deaths /
Live births x 100

56
Q

Mortality rate, neonatal

A

Neonatal deaths (<28 days)/
Live births
X100

57
Q

Mortality rate perinatal

A

Fetal deaths greater or equal to 28 wks GA + neonatal deaths less than 7 days /
Live births + fetal deaths greater than equal 28 wks gestation
X 100

58
Q

Negative predictive value

A

D/ (c+d) (true negative / false and true negative)

59
Q

Number needed to treat

A

1 /[ c/ (c + d) - a/( a+b)]

60
Q

Odds ratio

A

a x d/ b x c

61
Q

Positive predictive value

A

a / (a+b) ( true positive / true and false positive)

62
Q

Power

A

1- type II error (probability or rejecting the null hypothesis when the alternative hypothesis is true)

63
Q

Prevalence

A

of new cases at a point in time/ total population risk

64
Q

Risk ratio or relative risk

A

[a/a+b] /
[c/c+b]

65
Q

Sensitivity

A

a / a+c (TP/ TP+ FN) Fan blows the toilet paper in denominator )

66
Q

Specificity

A

D/ d+c ( true negative / (false positive + true negative) (tin man holds the flower pot in the denominator)

67
Q

Standard deviation

A

Square root of variance

68
Q

Standard error of the mean

A

Standard deviation / square root of number