Epithilium

Question 1

Stria vascularis

Answer 1

Special type of epithelium that is vascular. It’s located in cochlear duct and produces endolymph

Question 2

Simple squamous

Answer 2

Function: blood-brain barrier, filtration, exchange

Question 3

Simple cuboidal

Answer 3

Function: absorption, secretion, barriers, conduit
Location: thyroid follicles, renal tubules, ducts or glands

Question 4

Noncilitated simple columnar

Answer 4

Function: absorption, secretion, barrier
Location: stomach, intestine

Question 5

Ciliated simple columnar

Answer 5

Function: absorption, secretion, barrier
Location: uterine tubules

Question 6

Pseudostratified columnar

Answer 6

Function: secretion, absorption, barrier, transport
Location: trachea, bronchi, ducts of male reproductive system

Question 7

Stratified squamous (non-keratinized)

Answer 7

Function: barrier, protection
Location: esophagus, distal anal canal, vagina

Question 8

Stratified squamous (keratinized)

Answer 8

Function: barrier, protection
Location:epidermis

Question 9

Transitional (urothelium)

Answer 9

Function: barrier, protection, distension
Location: ureter, urinary bladder, urethra

Question 10

Metaplasia

Answer 10

When the epithelium changes from normal type to another type. Happens in smokers. May be difficult to transition to normal type again

Question 11

Specializations of the plasmalemma

Answer 11

Cilia, flagella, microvilla, stereocilia

Question 12

Motile cilium

Answer 12

Above array forms a basal body

Question 13

Primary/monocilium

Answer 13

Serve as chemosenseors, osmoreceptors, and mechanorecptors
Mediate light, taste, and sound perception
Pivotal role in normal tissue morphogenesis

Question 14

Primary cilium and polycystic kidney disease

Answer 14

Spindle changes orientation from being long and thin to short and wide

Question 15

Nodal cilia

Answer 15

Located at primitive node

Question 16

Zonulae occludentes

Answer 16

Extend along entire circumference of the cell. Precent material from taking paracellular route in passing from the lumen into the connective tissues.

Question 17

Zonulae adherentes

Answer 17

Baseal to zonulae occulendentes. E-cadherins bind to each other in the intercellular space and to actin filaments, intracellularly

Question 18

Maculae adherentes and focial adhesions

Answer 18

E-cadherins are associated with the plawue, Intermediate filaments form hairpin loops

Question 19

Gap junctions

Answer 19

communicating junctions for small moecules and ions to pass between cells. Couple adjacent cells metaolically and electrically

Question 20

Hemidesmosomes

Answer 20

Attach apithelial cells to underlying basal lamina

Question 21

Genes encoding for a specific caludin in renal epithelial cells results in what

Answer 21

excessive loss of magnesium ions in urine

Question 22

Brain cancers

Answer 22

loss of claudin 5

Question 23

Deafness

Answer 23

loss of claudin 9

Question 24

Cholera

Answer 24

ZO protein

Question 25

Paracellular pathway of movement

Answer 25

mixture of claudins to occludins dictates degree of permebaility

Question 26

Tight junctions establish what

Answer 26

functional polarity

Question 27

Bullous pephigoid

Answer 27

autoantibodies develop against type XVII collagen

Question 28

Pemphigus

Answer 28

all forms due to autoantibodies against desmogleins. Results in lots of blistering

Question 29

Based on the general blueprint for junctional complexes, what componenet does inegrin represent

Answer 29

Cell adhesion molecules (link protein)

Question 30

Clinical consequences of nexus or gap junctions

Answer 30

female infertility, neuropathy, deafness, congenital cataracts, cardiac arrhythmias