Cell Bio V

Question 1

Coating Protein I

Answer 1

Retrograde movement, from golgi back to ER

Question 2

Coating Protein II

Answer 2

entrograde movement, from ER to golgi

Question 3

SNAREs

Answer 3

used for direct movement

Question 4

v-SNARE

Answer 4

recognizes the t-SNARE at the golgi

Question 5

Reasons why we need retrograde flow

Answer 5

• Maintain membrane balance
• Recycle SNAREs so you don’t have to reuse them
• In case of misdelivery

Question 6

Botulinum toxin A

Answer 6

disrupts neurotransmission, gets rid of target SNARE. Causes muscle paralysis (botox)

Question 7

Mitochondrium

Answer 7

• Has outer and inner membrane
• Inner membrane has folding which are called cristis
• Not all cells have mitochondrium
• Have to stain in order to see

Question 8

High amounts of cristi means

Answer 8

making a high amount of ATP

Question 9

Low amounts of cristi means

Answer 9

making a low amount of ATP

Question 10

Where do CO and cyanide poisoning have an affect

Answer 10

enzymes on the inner MM

Question 11

Palocyte arrangemnt

Answer 11

looks like picket fense

Question 12

Tubular cristae

Answer 12

• Hallmark feature of cells that synthesize steriod hormones

- Will also find precursors of cholesterol (lipid droplets)

Question 13

What does steriod hormone synthesis require?

Answer 13

mitochondrial and sER enzymes

Question 14

MERRF

Answer 14

• Has red appearing mitochondria

- Has parking lot inclusions in mitochondria

Question 15

Functions of peroxisomes

Answer 15

• beta oxidation of FFAs
• plasmalogen synthesis
• regulate H2O2
• kill pathogens
• oxidize EtOH

Question 16

Zellweger syndrome

Answer 16

impaired import of enzymes into peroxisomes

Question 17

Cytoskeleton elements

Answer 17

microtubules and filaments

Question 18

Types of filaments

Answer 18

actin, intermediate, myosin

Question 19

Kinesin

Answer 19

microtubule motor. Takes synaptic vesicle from negative to positive end of the microtubule