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Cell Biology > Cell Bio VI > Flashcards

Cell Bio VI Flashcards

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1
Q

What is different in the Tau in Alzheimer’s

A

hyperphosphorylated

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2
Q

Phallacidin labels what

A

actin microfilaments (green)

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3
Q

MitoTracker red labels what

A

mitochondria (red)

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4
Q

DAPI stains what

A

nuclear DNA (blue)

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5
Q

Cytochalasins

A

inhibit actin polymerase

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6
Q

Cytokeratins are located where

A

epithelial cells

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7
Q

Desmin is located where

A

muscle (smooth and striated)

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8
Q

Glial gibrillary acid protein (GFAP) is located where

A

astrocytic glial cells

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9
Q

Neurofilament protein is located where

A

neurons

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10
Q

Nuclear lamin is located where

A

nucleus of all cells

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11
Q

Vimentin is located wehre

A

many mesodermal tissues

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12
Q

Neurofilaments

A

confer great tensile strength to axons. Form extensive cross bridges

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13
Q

Glial intermediate filaments

A

infrequent cross bridges

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14
Q

Mutations in keratin 5 or 14 gene do what

A

prevent keratin from assembling into strong networks. Epidermis becomes fragile/easily damages

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15
Q

Rosenthal’s fibers

A

Aggregates of GFAP and other proteins. Characteristic of pilocytic astrocytoma

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16
Q

Centrosome

A

lies next to the nucleus. Made of 9 triplet sets of microtubules

17
Q

Well differented tumor

A

more likely to be benign than poorly differentiated tumor

18
Q

PML bodies

A

involved in DNA repair and apoptosis

19
Q

Cajal bodies

A

involved in splicing

20
Q

Nuclear envelope

A
  • 2 lipid bilayer

- has outer membrane, perinucleur space, inner membrane, nuclear lamina, then chromatin

21
Q

Nuclear pore

A

Small materials can pass through easily

22
Q

Lamina

A

made of intermediate filament

23
Q

Heterochromatin

A

tightly coiled. Darker appearance

24
Q

Euchromatin

A

Not tightly coiled. Lighter appearance

25
Q

Orphan Annie Eye Nuclei

A

Hallmark of papillary thyroid cancer. Cells look empty.

Cell Biology (9 decks)

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