epithelial tissues

Question 1

epithelium

Answer 1

has a free surface, lines the body

Question 2

classifications of epithelium

Answer 2

simple or stratified squamous
simple or stratified cuboidal
simple, stratified, or pseudostratified columnar

Question 3

specific epithelial names

Answer 3

endocardium: lines atria & ventricles of heart
endothelium: lines blood and lymphatic vessels

Question 4

specific functions of epithelium to know

Answer 4

special sense: vision (retina)

Question 5

apical domain

Answer 5

microvilli, stereocilia, keratin

Question 6

keratin

Answer 6

protective acellular layer in skin, keeps skin hydrated

Question 7

cilila

Answer 7

associated w/ microtubules

Question 8

types of cilia

Answer 8

motile: move fluid and particles (nose, trachea, lungs)
nodal: embryonic development
primary: sensory

Question 9

microvilli

Answer 9

transport and absorption (kidney & intestines)

Question 10

stereocilia

Answer 10

hearing & balance (epididymis & inner ear)

Question 11

zonula occludens

Answer 11

-impermeable to ions & water
-like a zipper
-located closest to apical surface
-found on cornea epithelium

Question 12

zonula occludens passage

Answer 12

paracellular (between cells)
-aqueous channels (claudins)
-through junctions

Question 13

macula occludens

Answer 13

incomplete zonula occludens
-spot-like not zone-like (buttons)
-found in cornea endothelium

Question 14

cornea endothelial cells

Answer 14

responsible for pumping out water (requires ATP)

Question 15

Fuch’s endothelial dystrophy

Answer 15

edema in the cornea, leading to decreased vision
- caused by less water being pumped out by endothelial cells

Question 16

zonula adherens

Answer 16

lateral cell adhesion

Question 17

macula adherens (desmosomes)

Answer 17

strong attachment between cells laterally

Question 18

gap junctions

Answer 18

permits passage of ions and/or signal molecules through the cells
- action potential

Question 19

basal lamina components

Answer 19

• collagen type 4
• proteoglycans: chondroitin, dermatan, heparin, sulfate

Question 20

basal lamina junctions

Answer 20

-anchoring: focal adhesions, hemidesmosomes
-fibrillin microfibrils

Question 21

focal adhesions

Answer 21

-anchor actin to basement membrane
-migration during wound healing
-signal detection & transduction

Question 22

hemidesmosomes

Answer 22

anchor intermediate filaments into basement membrane

Question 23

what causes recurrent corneal erosions

Answer 23

abnormal hemidesmosomes

Question 24

fibrillin microfibrils in connective tissue

Answer 24

attach basal lamina to elastic fibers (damaged in Marfan syndrome)