Epithelial Tissue Flashcards
It is composed of closely aggregated polyhedral cells adhering strongly to one another and to a thin layer of ECM
Epithelial Tissue
What are the functions of Epithelium?
- Covering, lining, and protection
- Absorption
- Secretion
- Filtration
What characteristics are these; squamous, cuboidal, and columnar?
Shape
What characteristics are these; oval, spherical, and flattened?
Nuclei
What characteristics are these; basal pole, apical pole, and lateral surfaces?
Polarity
It is a thin extracellular, felt-like sheet of
macromolecules. A SEMIPERMEABLE FILTER for substances reaching epithelial cells from below.
Basement Membrane
What are the two parts of the Basement Membrane?
- Basal Lamina
- Reticular Lamina
It is composed of the cells responsible for the organ’s specialized functions, wherein the CELLS HAVE A SUPPORTING ROLE IN THE ORGAN.
Parenchymal and Stroma
What are the functions of Basement Membrane?
- Physical Support
- Cell Attachment
- Filter
- Guide Cell Migration
SEALS ADJACENT CELLS TO ONE ANOTHER, controlling the passage of molecules between them; separate apical and basolateral membrane domains.
Tight Junction (Zonula Occludens)
PROVIDES POINTS LINKING THE CYTOSKELETON OF ADJACENT CELLS; strengthens and stabilizes nearby tight junctions.
Adherens Junction (Zonula Adherens)
Resembles a single “Spot-weld”, PROVIDES POINTS OF STRONG INTERMEDIATE FILAMENT coupling between adjacent cells, strengthening the tissue.
Desmosome (Muscula Adherens)
ANCHORS CYTOSKELETON to the basal lamina.
Hemidesmosome
ALLOWS DIRECT TRANSFER OF SMALL MOLECULES and ions from one cell to another.
Gap Junction (Nexus)
What are the MAJOR TRANSMEMBRANE LINK PROTEINS of Tight Junction (Zonula Occlodens)?
Occludins, Claudins, and ZO Proteins
What are the MAJOR TRANSMEMBRANE LINK PROTEINS of Adherens Junction (Zonula Adherens)?
Cadherin and Catenin
What are the MAJOR TRANSMEMBRANE LINK PROTEINS of Desmosome (Macula Adherens)?
Desmogleins and Desmocollin
What is the MAJOR TRANSMEMBRANE LINK PROTEINS of Hemidesmosome?
Integrins
What is the MAJOR TRANSMEMBRANE LINK PROTEINS of Gap Junction (Nexus)?
Connexin
It is SMALL MEMBRANE PROJECTIONS with cores of ACTIN FILAMENTS.
Microvilli
Where are Microvilli found in the body organs?
Small Intestine
It INCREASES THE SURFACE AREA AVAILABLE FOR ABSORPTION; a motion-detecting function best seen on the absorptive epithelial cells lining the male reproductive system.
Stereocilia